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1.
J Stomatol Oral Maxillofac Surg ; 121(1): 90-94, 2020 Feb.
Article in English | MEDLINE | ID: mdl-30825659

ABSTRACT

Inflammatory Myofibroblastic Tumour (IMT) is a rare entity of unknown aetiology and pathogenesis. It was initially described in the lung, although there have been reported cases affecting extra-pulmonary sites. The aetiology of IMT remains unclear, with current evidence suggesting that IMTs are neoplastic processes resulting from chromosomal translocations that often cause an overexpression of ALK tyrosine kinase. Histologically, a variably cellular myxoid morphology is common in these tumours, with the presence of inflammatory cell infiltrate. Clinically, symptoms are non-specific, although the presence of a swelling is frequently reported. Imaging studies are not very useful in the diagnosis, as they only describe the presence of a mass, and do not provide a definitive diagnosis. This article presents a case, of Inflammatory Myofibroblastic Tumour of the jaw, in a male patient aged 16 years.


Subject(s)
Granuloma, Plasma Cell , Jaw Neoplasms , Adolescent , Anaplastic Lymphoma Kinase , Humans , Male , Protein-Tyrosine Kinases , Receptor Protein-Tyrosine Kinases
2.
BMJ Case Rep ; 20182018 Apr 17.
Article in English | MEDLINE | ID: mdl-29666079

ABSTRACT

We present an extremely rare case of a 53-year-old woman with an intraoral superficial haemosiderotic lymphovascular malformation (SHLM), also known as hobnail haemangioma. SHLM is a rare, benign, vascular tumour first described as targetoid haemosiderotic haemangioma, with only a handful of cases reported to present in the oral cavity. The diagnosis was established following complete surgical excision of the lesion, and after 14 months, there are still no signs of recurrence. Although SHLM is an uncommon condition, accurate and timely diagnosis is valuable in distinguishing these lesions from their more serious competing differential diagnoses.


Subject(s)
Gingival Neoplasms/pathology , Hemangioma/pathology , Female , Gingival Neoplasms/blood supply , Gingival Neoplasms/surgery , Hemangioma/blood supply , Hemangioma/surgery , Humans , Immunohistochemistry , Middle Aged , Neoplasm Recurrence, Local/surgery , Rare Diseases/pathology , Rare Diseases/surgery , Treatment Outcome
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