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1.
Sensors (Basel) ; 20(1)2019 Dec 19.
Article in English | MEDLINE | ID: mdl-31861511

ABSTRACT

The mobile ad hoc communication in highly dynamic scenarios, like urban evacuations or search-and-rescue processes, plays a key role in coordinating the activities performed by the participants. Particularly, counting on message routing enhances the communication capability among these actors. Given the high dynamism of these networks and their low bandwidth, having mechanisms to predict the network topology offers several potential advantages; e.g., to reduce the number of topology propagation messages delivered through the network, the consumption of resources in the nodes and the amount of redundant retransmissions. Most strategies reported in the literature to perform these predictions are limited to support high mobility, consume a large amount of resources or require training. In order to contribute towards addressing that challenge, this paper presents a history-based predictor (HBP), which is a prediction strategy based on the assumption that some topological changes in these networks have happened before in the past, therefore, the predictor can take advantage of these patterns following a simple and low-cost approach. The article extends a previous proposal of the authors and evaluates its impact in highly mobile scenarios through the implementation of a real predictor for the optimized link state routing (OLSR) protocol. The use of this predictor, named OLSR-HBP, shows a reduction of 40-55% of topology propagation messages compared to the regular OLSR protocol. Moreover, the use of this predictor has a low cost in terms of CPU and memory consumption, and it can also be used with other routing protocols.

2.
Bioinformatics ; 22(14): 1803-4, 2006 Jul 15.
Article in English | MEDLINE | ID: mdl-16720587

ABSTRACT

MOTIVATION: AutoGrid/AutoDock is one of the most popular software packages for docking, but its automation is not trivial for tasks such as (1) the virtual screening of a library of ligands against a set of possible receptors; (2) the use of receptor flexibility and (3) making a blind-docking experiment with the whole receptor surface. This is an obstacle for research teams in the fields of Chemistry and the Life Sciences who are interested in conducting this kind of experiment but do not have enough programming skills. To overcome these limitations, we have designed BDT, an easy-to-use graphic interface for AutoGrid/AutoDock. AVAILABILITY: BDT is available for free, upon request, for non-commercial research.


Subject(s)
Models, Chemical , Models, Molecular , Protein Interaction Mapping/methods , Proteins/chemistry , Sequence Analysis, Protein/methods , Software , User-Computer Interface , Algorithms , Binding Sites , Computational Biology/methods , Computer Simulation , Ligands , Multiprotein Complexes/chemistry , Multiprotein Complexes/ultrastructure , Protein Binding , Protein Conformation , Proteins/ultrastructure
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