ABSTRACT
Renal carcinoma may develop metachronous distant metastases without evidence of regional or local disease recurrence. These lesions may be misdiagnosed because of its benign-like appearance and lack of evidence of other disease spread.
Subject(s)
Carcinoma, Renal Cell/secondary , Hand/pathology , Kidney Neoplasms/pathology , Skin Neoplasms/secondary , Aged , Brain Neoplasms/secondary , Carcinoma, Renal Cell/diagnosis , Carcinoma, Renal Cell/surgery , Female , Hand Injuries/complications , Humans , Kidney Neoplasms/surgery , Nephrectomy , Skin Neoplasms/diagnosis , Skin Neoplasms/surgeryABSTRACT
Incidence of renal carcinoma, one of the most fatal solid neoplasms, has steadily increased in Western society. Moreover, these tumors are being increasingly detected in their early stages. As with most cancers, the underlying causes of the disease remain unknown. However, understanding of pathogenesis of this tumor is rapidly advancing, and will allow for new treatments for advanced disease. Understanding of the influence of easily avoidable risk factors may allow for prevention of thousands of deaths caused by renal cancer.
Subject(s)
Kidney Neoplasms/epidemiology , Humans , Kidney Neoplasms/etiology , Risk Factors , Spain/epidemiologyABSTRACT
El carcinoma renal constituye una de las neoplasias sólidas más letales. En la sociedad occidental se ha producido un constante aumento de la incidencia de este tumor, además de un incremento en la detección de tumores en estadíos precoces. Como ocurre en la mayoría de los cánceres, las causas de la enfermedad permanecen en gran medida desconocidas. Sin embargo, el conocimiento sobre la patogenia última de este tumor avanza rápidamente, permitiendo nuevos tratamientos para la enfermedad avanzada. El conocimiento de la influencia de factores de riesgo fácilmente evitables puede permitir evitar miles de muertes causadas por el cáncer renal (AU)
Incidence of renal carcinoma, one of the most fatal solid neoplasms, has steadily increased in Western society. Moreover, these tumors are being increasingly detected in their early stages. As with most cancers, the underlying causes of the disease remain unknown. However, understanding of pathogenesis of this tumor is rapidly advancing, and will allow for new treatments for advanced disease. Understanding of the influence of easily avoidable risk factors may allow for prevention of thousands of deaths caused by renal cancer (AU)