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Prevalence of Clostridioides difficile associated diarrhea in hospitalized patients in five Brazilian centers: A multicenter, prospective study.

Girão, Evelyne Santana; de Melo Tavares, Bruno; Alves Dos Santos, Sania; Gamarra, Gessica Lorena; Rizek, Camila; Martins, Roberta Cristina; Perdigão Neto, Lauro Vieira; Diogo, Constancia; Annibale Orsi, Tatiana D'; Sanchez Espinoza, Evelyn Patricía; Paz Morales, Hugo Manuel; da Silva Nogueira, Keite; Maestri, Adriane Ceshin; Boszczowski, Icaro; Piastrelli, Filipe; Costa, Cecilia Leite; Costa, Daniely Viana; Maciel, Geovania; Romão, Janete; Guimarães, Thais; Anne de Castro Brito, Gerly; Costa, Silvia Figueiredo.

Anaerobe ; 66: 102267, 2020 Dec.

Article in English | MEDLINE | ID: mdl-33080372

ABSTRACT

Epidemiological data on CD infection (CDI) in Latin American are scarce. CDI prevalence and strains characterization were prospectively evaluated in 5 Brazilian hospitals from different regions. Prevalence rates of CDI were 15%, ranging from 0 to 37%. ST42 was the most common Sequence Type and hypervirulent strains were not identified.

Subject(s)

Clostridioides difficile/classification , Clostridium Infections/epidemiology , Diarrhea/epidemiology , Adolescent , Adult , Aged , Aged, 80 and over , Anti-Bacterial Agents/therapeutic use , Bacterial Proteins/genetics , Bacterial Toxins/genetics , Brazil/epidemiology , Clostridioides difficile/drug effects , Clostridioides difficile/isolation & purification , Clostridium Infections/diagnosis , Clostridium Infections/drug therapy , DNA, Bacterial , Diarrhea/microbiology , Feces/microbiology , Female , Glutamate Dehydrogenase/genetics , Hospitals , Humans , Male , Middle Aged , Prevalence , Prospective Studies , Whole Genome Sequencing , Young Adult

ABSTRACT

Subject(s)

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