[Much ado about nothing]. / Molto rumore per nulla.

The professional routine often allows us to forget over time not only the name, but often also the pathology for which a patient has recovered from and treated for with much "love and dedication". However some cases contribute to the baggage of a good doctor's experience and become nearly "proverbial" in nature. A 50 year old woman, affected by chronic cholecystitis and under suspicion of neoplasia of the cholecyst, came studied and subordinated to cholecystectomy approximately a year ago. As per William Shakespeare's comedy "Much Ado About Nothing", also in this case numerous resources have been inefficiently used and precious diagnostic tools, instead of clearing our doubts and confirming the diagnosis, perhaps due to the lack of experience and also for the fear of the medical-legal reactions, they assumed otherwise. Now, thinking about this case, makes us smile. We shouldn't forget that, in accordance with what we remember from our Masters, often the most probable pathology is also that most frequent one.

Recurrent intussusception of the sigmoid colon caused by a transanal protruding sessile tubulo-villous malignant polyp.

We report a case of a 35 year-old woman with a large malignant sessile tubulo-villous polyp of the proximal end of a dolico-sigmoid colon causing intussusception and transanal prolapsing. The diagnosis presented some difficulties being the intussusception intermittent. The clinical feature had been initially misdiagnosed for a very large bleeding polyp (5 cm in size), protruding out of the anus with a long pedicle in the rectum. The histology of multiple bioptic samples of the lesion revealed malignancy. Conventional radiologic studies (plain x-rays, barium enema) after metal clips had been placed on the head of the polyp before it rose up the colon, led to the correct diagnosis without, nevertheless, documenting intussusception. An elective surgical resection of the dolico-sigmoid colon allowed the correct diagnosis and the curative treatment of the colonic intussusception and the malignancy.