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1.
Foot Ankle Surg ; 26(5): 551-555, 2020 Jul.
Article in English | MEDLINE | ID: mdl-31371267

ABSTRACT

BACKGROUND: Percutaneous osteotomy of calcaneus has been proposed to reduce the complication rate and became more and more popular. The bone cut can be performed as a straight or chevron-like (V) osteotomy using a Shannon burr. Comparative studies of straight or V-osteotomy as like as one or two screws in percutaneous calcaneal osteotomies are missing in the literature. We hypothesize that the V-osteotomy will result in a higher stiffness in biomechanical testing as the straight osteotomy using single screw for fixation. METHODS: The straight osteotomy (9 fresh-frozen specimens) and V-osteotomy (9 fresh-frozen specimens) was performed and the calcaneal tuberosity was moved 10mm medially and slightly rotated. One 6,5mm cancellous compression screw was used for osteosynthesis. Specimens were preconditioned with 100N over 100 cycles. The force was increased after every 100N by 100N from 200 to 500N. This was followed by cyclic loading with 600N for 500 cycles. RESULTS: Despite the higher mean values of the group with V-osteotomy, no significant difference was registered between the two groups regarding the stiffness at all force levels. A higher failure rate was observed in the group with straight osteotomy. CONCLUSION: The moderate correlation of bone density and stiffness in the V-group, and significantly lower failure rate with no secondary dislocation in fluoroscopy indicates the superiority of the V-osteotomy in the present study. Whether the demonstrated advantages can be reflected in clinical practice should be investigated in further studies. LEVEL OF CLINICAL EVIDENCE: 5.


Subject(s)
Bone Screws , Calcaneus/surgery , Fracture Fixation, Internal/methods , Osteotomy/methods , Aged, 80 and over , Biomechanical Phenomena , Calcaneus/physiopathology , Female , Humans , Male , Pressure
2.
Praxis (Bern 1994) ; 99(24): 1507-11, 2010 Dec 01.
Article in French | MEDLINE | ID: mdl-21125536

ABSTRACT

An 88 years old woman was admitted for muscular pain and weakness. She was under a treatment of simvastatin and was recently prescribed clarithromycin for a lung infection. The diagnosis of statin induced rhabdomyolysis by drug interaction was made. The evolution is good with eviction of the statin and aggressive hydratation. This case shows how important it is to know the risks factors and drug interactions predisposing to statin-induced myopathy.


Subject(s)
Anti-Bacterial Agents/adverse effects , Anticholesteremic Agents/adverse effects , Clarithromycin/adverse effects , Muscle Weakness/chemically induced , Pain/chemically induced , Rhabdomyolysis/chemically induced , Rhabdomyolysis/diagnosis , Simvastatin/adverse effects , Aged, 80 and over , Anti-Bacterial Agents/therapeutic use , Anticholesteremic Agents/therapeutic use , Clarithromycin/therapeutic use , Diagnosis, Differential , Drug Interactions , Drug Therapy, Combination , Female , Humans , Simvastatin/therapeutic use
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