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1.
World Neurosurg ; 141: e589-e599, 2020 09.
Article in English | MEDLINE | ID: mdl-32526358

ABSTRACT

BACKGROUND: Carotid artery stenting (CAS) is an established procedure for the treatment of atherosclerotic disease affecting the extracranial internal carotid artery. Recent population-based studies have suggested that long-term survival after CAS may be limited, thereby questioning its efficacy in a real-world scenario. METHODS: We retrospectively reviewed outcomes of patients undergoing CAS for asymptomatic or symptomatic carotid stenosis by a neurosurgeon or interventional neuroradiologist at our institution between 2008 and 2018. Patient and disease characteristics were recorded, as was the incidence of periprocedural and overall ischemia and mortality after CAS. Risk factors for recurrent ischemia and mortality were identified using a Cox proportional hazards model. RESULTS: There were 238 patients who met inclusion criteria. Mean age was 69.7 years and most patients were male (69.7%); 62.2% underwent CAS for symptomatic carotid stenosis. The use of CAS for treatment of asymptomatic stenosis declined over the study period (P = 0.006). Fourteen patients (5.9%) experienced new or recurrent ipsilateral ischemia during follow-up, with 8 (3.4%) experiencing a stroke with permanent neurologic deficit. Fifty-nine patients (24.8%) died during follow-up, with a median time to death of 111.3 months (95% confidence interval [CI], 95.1-133.6) on Kaplan-Meier analysis. Increasing age at time of CAS (unit risk ratio, 1.05; 95% CI, 1.01-1.10; P = 0.011) and comorbid congestive heart failure (risk ratio, 2.40; 95% CI, 1.39-4.13; P = 0.002) were independent risk factors for mortality during follow-up. CONCLUSIONS: Unlike population-based studies, our results indicate acceptable long-term survival after CAS in adequately selected patients.


Subject(s)
Carotid Stenosis/mortality , Carotid Stenosis/surgery , Endarterectomy, Carotid/mortality , Endarterectomy, Carotid/trends , Stents/trends , Adult , Aged , Aged, 80 and over , Endarterectomy, Carotid/adverse effects , Female , Follow-Up Studies , Humans , Male , Middle Aged , Mortality/trends , Retrospective Studies , Stents/adverse effects
2.
World Neurosurg ; 138: 309-312, 2020 06.
Article in English | MEDLINE | ID: mdl-32217181

ABSTRACT

BACKGROUND: Vertebral arteriovenous fistulas (VAVFs) are uncommon high-flow communications between a vertebral artery and surrounding venous plexus that occur spontaneously or secondary to trauma. CASE DESCRIPTION: A woman aged 57 years presented with a multiday history of rapidly progressive numbness and weakness in the left C5-C6 dermomyotomes. Her physical examination findings and subsequent electrophysiological testing were suggestive of a brachial radiculoplexopathy. Noninvasive imaging demonstrated venous congestion with multilevel compromise of the left-sided cervical foramina, and subsequent vertebral angiography confirmed a VAVF, which was treated with trapping of the involved vertebral artery segment. Her numbness and weakness progressively improved with concurrent involution of the dilated veins. CONCLUSIONS: This is a rare case of VAVF manifesting as a brachial radiculoplexopathy. Although rare, VAVF may be considered as a potential cause in patients presenting with similar symptoms.


Subject(s)
Arteriovenous Fistula/pathology , Vertebral Artery/abnormalities , Angiography , Arteriovenous Fistula/diagnosis , Arteriovenous Fistula/surgery , Brachial Plexus Neuropathies/diagnosis , Diagnosis, Differential , Embolization, Therapeutic/methods , Female , Humans , Middle Aged , Radiculopathy/diagnosis
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