ABSTRACT
El aumento de volumen en la región frontal puede deberse a múltiples etiologías, dentro de las cuales deben considerarse: mucocele, tumor de Pott-Puffy, lesiones fibro-óseas, tumores de nariz y senos paranasales, lesiones intracraneales y metástasis. El objetivo del estudio fue describir el protocolo clínico empleado en los pacientes que se presentaron con aumento de volumen frontal y una propuesta de estadificación de las lesiones inflamatorias. Se realizó un estudio retrospectivo observacional. Se encontraron 7 casos con aumento de volumen en la región frontal: 4 casos secundarios a enfermedad inflamatoria (3 casos tumor de Pott-Puffy, un mucocele frontal) y 3 por neoplasia (un caso benigno y 2 malignos). Es muy importante considerar, entre los diagnósticos diferenciales de aumento de volumen en la región frontal, enfermedades inflamatorias que pueden representar una complicación grave de infecciones nasosinusales o neoplasias malignas avanzadas. Se propone un sistema de estadificación de las lesiones inflamatorias frontales (AU)
Frontal swelling can be due to multiple etiologies, including: mucocele, Pott's puffy tumor, fibro osseous lesions, benign and malignant neoplasms of the nose and paranasal sinuses, intracranial lesions, and metastasis. The objective of this study was to describe the clinical protocol used for the diagnosis of patients presented with frontal swelling and the proposal for staging of inflammatory lesions. We performed an observational retrospective analysis. We found 7 cases of patients with frontal swelling: 4 cases secondary to inflammatory pathology (3 Potts puffy tumors and one frontal mucocele), and 3 cases secondary to neoplasms (one benign and 2 malignant neoplasms). It's very important to consider the wide differential diagnosis that can present as frontal swelling, from inflammatory pathologies secondary to possible advanced infections of the paranasal sinuses to invasive malignant neoplasms. We propose a system of staging of frontal inflammatory lesions (AU)
Subject(s)
Humans , Male , Female , Frontal Sinusitis/diagnosis , Frontal Sinusitis/etiology , Frontal Sinusitis/therapy , Frontal Sinus/injuries , Pott Puffy Tumor/surgery , Pott Puffy Tumor/etiology , Osteoma/diagnosis , Diagnosis, Differential , Osteoma/therapy , Mucocele/diagnosis , Mucocele/therapy , Paranasal Sinus Neoplasms/diagnosis , Paranasal Sinus Neoplasms/therapy , Neoplasm Metastasis/pathology , Neoplasm Metastasis/therapy , Retrospective Studies , Observational Study , Magnetic Resonance Spectroscopy/methodsABSTRACT
Frontal swelling can be due to multiple etiologies, including: mucocele, Pott's puffy tumor, fibro osseous lesions, benign and malignant neoplasms of the nose and paranasal sinuses, intracranial lesions, and metastasis. The objective of this study was to describe the clinical protocol used for the diagnosis of patients presented with frontal swelling and the proposal for staging of inflammatory lesions. We performed an observational retrospective analysis. We found 7 cases of patients with frontal swelling: 4 cases secondary to inflammatory pathology (3 Potts puffy tumors and one frontal mucocele), and 3 cases secondary to neoplasms (one benign and 2 malignant neoplasms). It's very important to consider the wide differential diagnosis that can present as frontal swelling, from inflammatory pathologies secondary to possible advanced infections of the paranasal sinuses to invasive malignant neoplasms. We propose a system of staging of frontal inflammatory lesions.
Subject(s)
Edema/etiology , Forehead , Frontal Bone/pathology , Mucocele/pathology , Paranasal Sinus Neoplasms/pathology , Pott Puffy Tumor/pathology , Algorithms , Carcinoma, Papillary/complications , Carcinoma, Papillary/diagnostic imaging , Carcinoma, Papillary/pathology , Carcinoma, Papillary/secondary , Cellulitis/diagnostic imaging , Cellulitis/etiology , Cross-Sectional Studies , Diagnosis, Differential , Edema/diagnostic imaging , Fibrous Dysplasia, Monostotic/complications , Fibrous Dysplasia, Monostotic/diagnostic imaging , Fibrous Dysplasia, Monostotic/pathology , Forehead/diagnostic imaging , Frontal Bone/diagnostic imaging , Humans , Magnetic Resonance Imaging , Mucocele/complications , Mucocele/diagnostic imaging , Nose Neoplasms/complications , Nose Neoplasms/diagnostic imaging , Nose Neoplasms/pathology , Papilloma, Inverted/complications , Papilloma, Inverted/diagnostic imaging , Papilloma, Inverted/pathology , Paranasal Sinus Neoplasms/complications , Paranasal Sinus Neoplasms/diagnostic imaging , Pott Puffy Tumor/complications , Pott Puffy Tumor/diagnostic imaging , Retrospective Studies , Sinusitis/complications , Sinusitis/diagnostic imaging , Skull Neoplasms/complications , Skull Neoplasms/diagnostic imaging , Skull Neoplasms/pathology , Thyroid Neoplasms/pathology , Tomography, X-Ray ComputedABSTRACT
PURPOSE: The aim of this study was to compare the efficacy and safety of moxifloxacin with that of amoxicillin/clavulanate for the treatment of acute bacterial sinusitis in adults. MATERIALS AND METHODS: Five hundred seventy-five patients from Latin American countries were randomized to receive oral moxifloxacin 400 mg once daily for 7 days, or oral amoxicillin/clavulanate 500/125 mg 3 times daily for 10 days, in a prospective, open study. RESULTS: At the test-of-cure visit (7-14 days after the end of therapy), the clinical success rate in the moxifloxacin group was 93.4% similar to that in the amoxicillin/clavulanate group (92.7%). Documented bacteriological eradication plus presumed eradication rates in the moxifloxacin (96.5%) and the amoxicillin/clavulanate (96.7%) groups were also similar. Drug-related adverse events were recorded in 32.2% of patients in the moxifloxacin group and 29.7% in the amoxicillin/clavulanate group. Patient discontinuation in the trial due to adverse events occurred for 10 patients in the moxifloxacin group and 6 in the amoxicillin/clavulanate group. CONCLUSIONS: Overall, in terms of clinical and bacteriological response, moxifloxacin was equivalent to amoxicillin/clavulanate for the treatment of acute bacterial sinusitis in adults.
Subject(s)
Amoxicillin-Potassium Clavulanate Combination/therapeutic use , Anti-Bacterial Agents/therapeutic use , Aza Compounds/therapeutic use , Quinolines/therapeutic use , Sinusitis/drug therapy , Acute Disease , Adolescent , Adult , Female , Fluoroquinolones , Humans , Male , Middle Aged , Moxifloxacin , Prospective Studies , Sinusitis/microbiologyABSTRACT
Propósito: El objetivo del estudio fue valorar si existía aumento de la presión intraocular en pacientes con el diagnóstico de rinitis que se encontraban bajo tratamiento con dipropionato de beclometasona aplicado a 400 mcg al día por vía nasal. Material y Métodos: Se seleccionaron 60 pacientes con el diagnóstico de rinitis sin importar la etiología, de entre 18 y 60 años de edad. Los pacientes se dividieron mediante un proceso aleatorio en dos grupos de 30 pacientes cada uno. El primer grupo recibió dipropionato de beclometasona. El segundo grupo recibió placebo. A todos los pacientes se les realizó tonometría por aplanamiento a las 3, 6 12, 26 y 52 semanas. Resultados: Se encontró que las variaciones de la presión intraocular en ambos grupos estuvieron dentro de limites de referencia. El promedio de la presión intraocular no mostró diferencias significativas en las mediciones realizadas de las 3 a las 52 semanas (p = 0.473). Conclusión: El dipropionato de beclometasona en aplicación tópica nasal no aumenta significativamente la presión intraocular, incluso después de un año de tratamiento
