ABSTRACT
Male rats were exposed to fractionated 0.1 Gy radiation in early onthogenesis (1 month). Essential changes in reproductive system and liver were found. First generation offspring of the exposed males and females showed moderate radiation changes more expressed in immature rats.
Subject(s)
Genitalia, Male/radiation effects , Liver/radiation effects , Paternal Exposure , Age Factors , Animals , Cesium Radioisotopes , DNA/radiation effects , Data Interpretation, Statistical , Dose Fractionation, Radiation , Female , Genitalia, Male/enzymology , Genitalia, Male/metabolism , L-Lactate Dehydrogenase/metabolism , Liver/enzymology , Liver/metabolism , Male , RNA/radiation effects , Radiation Dosage , Rats , Succinate Dehydrogenase/metabolismABSTRACT
We studied the effects of sodium succinate on the reproductive system and blood leukocyte count in rats 30 and 60 days after fractionated irradiation in a dose of 1 Gy. Sodium succinate in concentrations of 0.2 and 0.5% was given ad libitum with water before (1 week) and during irradiation (5 days). The preparation promoted morphofunctional recovery of the testes and epididymides and restored the count of peripheral blood leukocytes.
Subject(s)
Genitalia, Male/drug effects , Genitalia, Male/radiation effects , Radiation Injuries, Experimental/drug therapy , Succinic Acid/therapeutic use , Animals , Genitalia, Male/enzymology , L-Lactate Dehydrogenase/metabolism , Male , Rats , Sperm Count , Succinic Acid/pharmacologyABSTRACT
It was studied the morphofunctional state of rat male reproductive system after chronically exposure to low intensive gamma-irradiation in early ontogenesis. After radiation with a total dose of 1.0 Gy it was revealed the decrease of the testes and epididymis weight, dysbalance in the ratio of different spermatogenic cells, changes in nucleic acid content and discoordination of bioenergetic metabolism in testes. Disturbance in rat male reproductive system retained in remote period (180 days after irradiation).
Subject(s)
Epididymis/radiation effects , Spermatogenesis/radiation effects , Spermatozoa/radiation effects , Testis/radiation effects , Animals , DNA/radiation effects , Data Interpretation, Statistical , Epididymis/metabolism , Epididymis/pathology , Epididymis/physiology , Male , Organ Size , Radiation Dosage , Rats , Spermatids/radiation effects , Spermatocytes/radiation effects , Spermatogonia/radiation effects , Testis/metabolism , Testis/pathology , Testis/physiology , Time FactorsSubject(s)
Amputation, Surgical/methods , Leg/surgery , Amputation Stumps , Humans , Reoperation , ThighABSTRACT
Luminescent investigation data of the tissue blood circulation and microcirculation in the limbs in 29 patients (in 25 of them with the main arteries occlusion) were adduced. Significance of the luminescent investigation of the limbs blood circulation in the diagnosis of the tissue blood circulation and microcirculation infringement degree was determined.
