Short Latency Radiation Induced Osteosarcoma Detected on 18F-FDG PET/CT Scan in Solitary Plasmacytoma.

18Fluorine-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) plays a pivotal role in the staging, restaging, and surveillance of various bone tumors, including plasmacytomas and osteosarcomas. Solitary plasmacytomas most frequently occur in the bones and are primarily treated with either surgery or radiotherapy. Radiation-induced osteosarcomas (RIOS) usually develop after a median interval of 11 years between radiation and sarcoma presentation. However, these can rarely present with a short latent period of 4 years or even lesser. In such cases, whole-body imaging plays a vital role in the early detection and management of RIOS. Herein, we present the case of a 29-year-old female patient with solitary plasmacytoma undergoing a follow-up whole-body 18F-FDG PET/CT, which revealed metastatic RIOS after a short latent period.

Complete splenic vein tumour thrombus in primary gastric malignancy on F18-fluorodeoxyglucose positron emission tomography-computed tomography.

Tumour thrombus is an uncommon complication with ominous outcomes. F18 FDG PET-CT scan helps in differentiating tumour thrombus from venous thrombus owing to its metabolic uptake similar to the tumour. We discuss an interesting case of gastric malignancy with complete splenic vein tumour thrombosis on initial presentation.

Seeding in the walnut; Leptomeningeal spread of Breast Cancer.

Breast cancer is the most common etiology of leptomeningeal carcinomatosis (LC), with or without brain parenchymal involvement. However, only 5% of patients with breast cancer develop leptomeningeal metastasis even in late clinical course. It can rarely be detected on bone scintigraphy. MRI is the modality of choice.

Pyrexia of unknown origin as clinical presentation of Renal Cell Carcinoma: Role of F18-FDG PET/CT.

The synergy of the anatomic-metabolic details provided by PET-CT plays a substantial role in the diagnostic workup of Pyrexia of Unknown Origin (PUO). Although several imaging modalities have been used in the detection of cause of PUO, PET-CT is the most sensitive and specific modality for detection of cause. RCC is a rare cause of PUO.

The Hot Pleura: Isolated Pleural Metastases From Renal Cell Carcinoma.

Renal cell carcinoma (RCC) is the most common solid renal malignancy that metastasizes typically to lungs, bones, liver, adrenals, and lymph nodes. Isolated pleural metastases of RCC are extremely rare, with only few cases reported in the literature. We report one such case of a 60-year-old woman, a known case of RCC of the left kidney who underwent nephrectomy, and on follow-up, PET/CT scan revealed diffuse thick nodular hypermetabolic left pleural thickening, which was later biopsied and turned out to be pleural metastases from RCC. No other site of metastases was found.

A rare presentation of osseous metastasis in Hepatocellular Carcinoma (HCC) on bone scintigraphy.

Bone metastases in HCC are uncommon with an incidence of 3% to 20%. Screening for bone metastasis is not a routine practice. Diagnosis is often delayed, and usually made once symptoms develop.