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1.
Clin Med (Lond) ; 17(2): 121-125, 2017 Apr.
Article in English | MEDLINE | ID: mdl-28365620

ABSTRACT

This study provides detailed data on the current characteristics, perceptions and outcomes of 45 young people with cystic fibrosis (CF) as they transition into adulthood. Although many had severe disease, they generally coped well, found attendance at a transition clinic helpful and welcomed the increased independence of an adult healthcare environment. Levels of psychological distress were low with only 15.6% having anxiety and 6.7% depression. The main psychological coping strategy used was optimistic acceptance. Overall, most remained stable after transfer but 33% had some decline in lung function and 9% in nutritional status, requiring intensification of treatment. They had high levels of satisfaction with their relationships and life situations and 76% were in employment or education. These results are encouraging and as life expectancy improves, young adults with CF are coping well with transition into adulthood.


Subject(s)
Adaptation, Psychological , Cystic Fibrosis , Adolescent , Adult , Chronic Disease , Cohort Studies , Cystic Fibrosis/epidemiology , Cystic Fibrosis/psychology , Cystic Fibrosis/therapy , Female , Humans , Male , Personal Satisfaction , Transition to Adult Care , Young Adult
2.
J Behav Ther Exp Psychiatry ; 54: 170-177, 2017 03.
Article in English | MEDLINE | ID: mdl-27569740

ABSTRACT

BACKGROUND & OBJECTIVES: Ruminative self-focus is a maladaptive form of emotional processing and is linked to distress, whereas mindful self-focus is adaptive and linked to low distress. However, the effects of these different modes of self-focus have not yet been examined in symptoms associated with psychotic disorders, such as paranoid ideation. This study aimed to explore whether inducing ruminative self-focus maintains paranoid ideation whilst inducing mindful self-focus reduces paranoid ideation. METHOD: Thirty-two non-clinical participants engaged in a paranoia induction prime and then took part in an eight-minute ruminative self-focus induction and an eight-minute mindful self-focus induction. RESULTS: Following an induction of paranoia, mindful self-focus significantly decreased levels of paranoia, whereas ruminative self-focus had no significant impact on levels of paranoia, and therefore was interpreted as having maintained paranoia. LIMITATIONS: The study used non clinical participants and the level of paranoid ideation experienced was fairly mild, which limits generalisation to clinical levels of distress. Additionally, the mechanism by which rumination and mindful self-focus have their effects was not examined. CONCLUSIONS: The results add to the growing body of evidence that there are two distinct modes of self-focus that have differential effects on emotional processing. These findings also demonstrate the potential benefit of interventions targeting rumination in paranoid ideation with mindful self-focus.


Subject(s)
Affect/physiology , Attention/physiology , Awareness/physiology , Paranoid Disorders/psychology , Self Concept , Adolescent , Female , Humans , Male , Visual Analog Scale , Young Adult
3.
Am J Geriatr Psychiatry ; 14(7): 582-8, 2006 Jul.
Article in English | MEDLINE | ID: mdl-16816011

ABSTRACT

OBJECTIVE: The objective of this study was to compare functional impairments in dementia with Lewy bodies (DLB) and Alzheimer disease (AD) and their relationship with motor and neuropsychiatric symptoms. METHODS: The authors conducted a cross-sectional study of 84 patients with DLB or AD in a secondary care setting. Patients were diagnosed according to published criteria for DLB and AD. The Bristol Activities of Daily Living Scale (BADLS) was used to assess functional impairments. Participants were also assessed using the Unified Parkinson's Disease Rating Scale (motor section), the Neuropsychiatric Inventory, and the Mini-Mental Status Examination. RESULTS: Patients with DLB were more functionally impaired and had more motor and neuropsychiatric difficulties than patients with AD with similar cognitive scores. In both AD and DLB, there were correlations between total BADLS scores and motor and neuropsychiatric deficits. There was more impairment in the mobility and self-care components of the BADLS in DLB than in AD, and in DLB, these were highly correlated with UPDRS score. In AD, orientation and instrumental BADLS components were most affected. CONCLUSION: The nature of functional disability differs between AD and DLB with additional impairments in mobility and self-care in DLB being mainly attributable to extrapyramidal motor symptoms. Consideration of these is important in assessment and management. Activities of daily living scales for use in this population should attribute the extent to which functional disabilities are related to cognitive, psychiatric, or motor dysfunction.


Subject(s)
Alzheimer Disease/epidemiology , Alzheimer Disease/physiopathology , Basal Ganglia Diseases/epidemiology , Basal Ganglia Diseases/physiopathology , Brain/physiopathology , Lewy Body Disease/epidemiology , Lewy Body Disease/physiopathology , Activities of Daily Living , Aged , Alzheimer Disease/diagnosis , Basal Ganglia Diseases/diagnosis , Cross-Sectional Studies , Demography , Female , Humans , Lewy Body Disease/diagnosis , Male , Severity of Illness Index , Surveys and Questionnaires
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