Anticoagulation strategy in patients with atrial fibrillation after carotid endarterectomy.

Aim: Carotid artery stenosis and atrial fibrillation are diseases of the aging patient population. Literature lacks precise anticoagulation treatment protocols for patients with atrial fibrillation following carotid endarterectomy. We present our experiences with anticoagulation strategy in this particular patient population. Patients and methods: Between June 2001-September 2017, 165 patients with chronic or paroxysmal atrial fibrillation out of 1594 cases from three different institutions whom received Coumadin and aspirin and required carotid endarterectomy were reviewed, respectively. Mean age was 63.4 ± 7.9 years. Male/female ratio was 102/63. There were 67 diabetic and 138 hypertensive cases. Results: Patients are followed a mean of 64.4 ± 16.9 months. Early mortality occurred in two patients due to intracranial bleeding and heart failure. Another patient was lost due to intracerebral hemorrhage and 16 other patients died due to various causes in the late follow-up. Three patients required exploration against bleeding. Conclusion: Combination of warfarin with an aim to keep the INR value between 2 and 3, and aspirin at a dosage of 100 mg per day seemed feasible and in our modest patient cohort. Further studies including multicenter larger data are warranted in order to establish a precise anticoagulation treatment protocol for patients with atrial fibrillation after carotid endarterectomy.

Traumatic posterior tibial artery occlusion in a soccer player: A case report.

A 24-year-old male professional soccer player sustained a right ankle contusion due to blunt kick toward the medial malleolus level during a soccer game. He stopped playing due to pain, coldness, and paresthesia on his right foot. Computed tomography angiography revealed a 4.5 cm occlusion on the posterior tibial artery at the right ankle level of which the distal segment was filled with collateral arteries. After the diagnosis of the traumatic occlusion, the patient underwent angiography for recanalization with thrombolysis in an external center, which was unsuccessful. Crural artery injuries after blunt sport traumas are very rare. In knee and ankle traumas with ischemic symptoms, vascular injuries should be excluded with prompt examination.

Midterm results of aortic valve replacement with cryopreserved homografts.

OBJECTIVE: The aim of this study was to analyze the midterm clinical results of aortic valve replacement with cryopreserved homografts. MATERIALS AND METHODS: Aortic valve replacement was performed in 40 patients with cryopreserved homograft. The indications were aortic valve endocarditis in 20 patients (50%), truncus arteriosus in 6 patients (15%), and re-stenosis or regurtitation after aortic valve reconstruction in 14 (35%) patients. The valve sizes ranged from 10 to 27mm. A full root replacement technique was used for homograft replacement in all patients. RESULTS: The 30-day postoperative mortality rate was 12.5% (5 patients). There were four late deaths. Only one of them was related to cardiac events. Overall mortality was 22.5%. Thirty-three patients were followed up for 67±26 months. Two patients needed reoperation due to aortic aneurysm caused by endocarditis. The mean transvalvular gradient significantly decreased after valve replacement (p<0.003). The last follow up showed that the 27 (82%) patients had a normal left ventricular function. CONCLUSION: Cryopreserved homografts are safe alternatives to mechanical valves that can be used when there are proper indications. Although it has a high perioperative mortality rate, cryopreserved homograft implantation is an alternative for valve replacement, particularly in younger patients and for complex surgical problems such as endocarditis that must be minimalized.

Mitral valve replacements in redo patients with previous mitral valve procedures: mid-term results and risk factors for survival.

OBJECTIVE: We aimed to investigate the risk factors for hospital mortality, short (five years) and mid-term (10 years) survival in patients who underwent mitral valve replacements in redo patients with previous mitral valve procedures. PATIENTS AND METHODS: Between September 1989 and December 2003, 62 redo patients have undergone mitral valve replacements due to subsequent mitral valve problems. Preoperative, operative, and postoperative data were analyzed retrospectively and evaluated for risk factors affecting hospital mortality, mid- and long-term survival. RESULTS: The hospital mortality was 6.4%. The one-, five-, and 10-year actuarial survival rates were 94%+/- 2%, 89%+/- 6%, and 81 +/- 9%. New York Heart Association (NYHA) functional class IV, low left ventricular ejection fraction (<35%), increased left ventricular end-diastolic diameter (LVEDD) > 50 mm, female gender, pulmonary edema, and urgent operations were found to be risk factors in short-term survival. NYHA functional class IV, low left ventricular ejection fraction, increased LVEDD, and increased left atrial diameter (LA > 60 mm) were risk factors in mid-term survival. CONCLUSION: Redo mitral valve surgery with mechanical prosthesis offers encouraging short- and mid-term survival. NYHA functional class IV, low left ventricular ejection fraction, and increased left ventricular diameters were especially associated with increased short- and mid-term mortality. Earlier surgical management before the development of severe heart failure and myocardial dysfunction would improve the results of redo mitral valve surgery.

Endovascular therapy for thoracic and abdominal aortic emergencies.

BACKGROUND: Emergent situations of both the thoracic and abdominal aortae are serious life-threatening situations. Endovascular stent graft repair offers an alternative to conventional operation for management of aortic diseases. Our aim was to report our experience with endovascular stent graft repair of thoracic and abdominal aortic emergencies. METHODS: Between April 2004 and March 2007, endovascular stent graft repair was performed in 16 patients (13 males, 3 females; mean age 61.4+/-16.3; range 38 to 86 years). The emergent lesions were in the thoracic aorta in 8 patients and abdominal aorta in the remainder. The deployed stent graft systems were Talent-Medtronic (n=8) and Excluder-Gore (n=8). RESULTS: Successful deployment of the stent grafts in the appropriate position was achieved in all patients. Hospital mortality occurred in 3 patients. There was no conversion to open surgery. The total number of endoleaks was 3 (18.75%). CONCLUSION: Endovascular stent graft placement is a feasible and effective approach in the emergency treatment of patients with complicated emergent pathologies of both thoracic and abdominal aortae.

Regional anesthesia in elderly patients undergoing carotid surgery: report of a case series.

BACKGROUND: This study evaluates the short-term results in patients more than 75 years of age undergoing carotid endarterectomy at a single institution. METHODS: Between June 2004 and June 2007, carotid endarterectomy operations were performed in 123 patients. A total of 70 patients had regional anesthesia. The data for all patients were retrospectively reviewed. Regional anesthesia and selective shunting was performed in all patients. RESULTS: In 6 patients, a shunt was required. Primary closure of the carotid artery was performed in 22 patients and patch angioplasty was used in the remainder. There were no postoperative neurological complications. One patient died due to myocardial infarction. CONCLUSIONS: Carotid endarterectomy with regional anesthesia can be performed safely in the elderly population with low mortality and morbidity. Regional anesthesia may have advantages over general anesthesia and could potentially aid in avoiding complications related to shunt use.

The role of antiendothelial cell antibodies in the development and follow-up of coronary and peripheral arterial diseases.

Occlusive lesions in the arterial endothelium are often caused by formation of intimal hyperplasia and fibrinoid necrosis. The objective of this study was to investigate the association between antiendothelial cell antibodies (AECAs) and the development of coronary artery disease (CAD) and peripheral artery disease (PAD). In this study, 94 patients with CAD or PAD and 94 healthy volunteers serving as control subjects were examined. Frozen sections of human umbilical vein endothelial cells and primate smooth muscle cells were used to detect the presence of AECAs, which were found in 52 of 94 patients (55%) and in 15 of 94 controls (16%) (P < .001). Endothelial structure tissue damage is a major factor in arterial diseases. In the present study, a statistically significant relationship was found between AECAs and the development of CAD and PAD. The presence of AECAs has been identified as a risk factor for these diseases. According to this study, AECAs are reliable prognosticators for the development of CAD and PAD. Further studies with large numbers of serum samples are under way.

Coronary bypass surgery in kawasaki disease in a four-year-old patient: case report.

Kawasaki disease is an acute vasculitis syndrome of unknown etiology that mainly affects small and medium-sized arteries, particularly the coronary arteries. This disease is rarely seen in infants and young people in Turkey. In this short report, we present a four-year-old patient who has Kawasaki disease associated with coronary artery aneurysm and underwent coronary bypass grafting.

Atherosclerosis of radial and internal thoracic arteries used in coronary bypass: atherosclerosis in arterial grafts.

BACKGROUND: This study aimed to evaluate the degree and incidence of atherosclerosis in internal thoracic (ITA) and radial arteries (RA) harvested for coronary bypass grafting. MATERIALS AND METHODS: The association of major clinical events and etiological factors for atherosclerosis was investigated in 770 arterial segments obtained prospectively from 480 patients. Potential risk factors for atherosclerosis were age, gender, smoking, diabetes mellitus, peripheral vascular disease, cerebrovascular disease, chronic renal failure, hypercholesterolemia, obesity, hypertension, and a positive family history. RESULTS: Six types of histological lesions have been defined; grade III or more was present in the RA in 47 (16%) patients and in the ITA in 30 (7%). The mean grade was 1.6 +/- 0.6 in the ITA and 2.1 +/- 0.9 in the RA (p < 0.001). CONCLUSION: RA had a significantly greater prevalence of atherosclerosis than the same patients' ITA. There was a strong correlation between ITA atherosclerosis and age. The presence of calcification may lead surgeons to avoid an extra incision according to risk factors, although most of these are not predictive.

Triple-valve procedures: impact of risk factors on midterm in a rheumatic population.

BACKGROUND: We aimed to determine the influence of preoperative, intraoperative, and postoperative variables on short and midterm results in patients undergoing triple-valve surgery. METHODS: Between September 1989 and December 2003, 157 patients underwent triple-valve surgery with mechanical prosthetic valves. Preoperative, operative, and postoperative data were retrospectively analyzed and risk factors affecting hospital mortality and short and midterm survival were evaluated. RESULTS: The hospital mortality was 2.5%. Multivariate analysis revealed that New York Heart Association functional class IV, low left ventricular ejection fraction (< 0.35) and increased left ventricular end diastolic diameter (> 50 mm Hg) were associated with increased short and midterm mortality. The freedom rate from reoperation and thromboembolic complications at 5 years were 93% +/- 4% and 81% +/- 7%, respectively. In echocardiographic assessments, significant decrease in left ventricular end-diastolic and end-systolic diameters (53.1 +/- 8.3 vs 50.1 +/- 7.1, p = 0.002 and 35.3 +/- 7.4 vs 32.6 +/- 7.2, p = 0.002) was observed. CONCLUSIONS: Triple-valve surgery offers satisfactory short and midterm results and prevents ventricular dilatation. Mortality significantly decreases if surgery is performed before left ventricle functions deteriorate.

Successful surgical treatment of massive pulmonary embolism after coronary bypass surgery.

Acute massive pulmonary embolism after cardiac surgery is very rare. Although accurate diagnosis and rapid treatment are crucial to a successful outcome, there is no standard treatment option. Thrombolytic therapy and catheter embolectomy are the usual treatment options, but they are associated with risks, especially in patients who experience massive pulmonary embolism after coronary artery bypass surgery. Open pulmonary embolectomy may be the best choice for treating these patients. This report describes our use of emergency pulmonary embolectomy along with cardiopulmonary bypass as an effective therapeutic approach in 2 cases of massive pulmonary embolism that occurred after on-pump coronary artery bypass grafting.