ABSTRACT
BACKGROUND: Lupus vulgaris is the most common form of cutaneous tuberculosis in adults. Lupus vulgaris is caused by hematogenous, lymphatic, or contiguous spread from elsewhere in the body. histologically it is charecterised by typical tubercles with or without caseation, surrounded by epitheloid histiocytes and multinucleate giant cells in the superficial epidermis with prominent peripheral lymphocytes. MATERIALS AND METHOD: All cases of clinically and histopathologicaly diagnosed lupus vulgaris over the previous five years were included in the study. RESULTS: Fourteen cases of lupus vulgaris cases reported during the study period with eaqual incidence among males and females. DISCUSSION: Plaque type of lupus vulgaris was the most common type. Histopathologically tubercular granulomas were seen in all cases as compared to other studies. CONCLUSION: Different patterns of lupus vulgaris are reported.
Subject(s)
Anti-Bacterial Agents/adverse effects , Anti-Inflammatory Agents, Non-Steroidal/adverse effects , Drug Eruptions/epidemiology , Tertiary Care Centers/statistics & numerical data , Adolescent , Adult , Aged , Female , Humans , India/epidemiology , Male , Middle Aged , Retrospective Studies , Young AdultABSTRACT
Pyoderma gangrenosum (PG) is a rare inflammatory disorder of unknown etiology characterized by neutrophilic infiltration of the dermis and destruction of tissue. PG is diagnosed after excluding more commonly occurring condition presenting with similar manifestation. Though PG has been reported to occur over the genitalia, it rarely presents with concurrent involvement of the groin. Herein, we present a case of PG masquerading as Donovanosis.
ABSTRACT
BACKGROUND: Inherited palmoplantar keratoderma are a rare group of disorder affecting the palm and sole characterised by hyperkeratosis resulting in severe disability and deformities. OBJECTIVE: To report a rare case of punctate palmoplantar keratoderma. METHOD: A case attending our OPD is reported. RESULT: Case report. CONCLUSION: This case is reported for its unique presentation and rarity.
Subject(s)
Keratoderma, Palmoplantar/genetics , Biopsy , Humans , Keratoderma, Palmoplantar/pathology , Male , Middle Aged , Skin/pathology , Young AdultSubject(s)
Myofibromatosis/diagnosis , Abnormalities, Multiple , Child , Consanguinity , Diagnosis, Differential , Humans , MaleSubject(s)
Hamartoma/congenital , Hamartoma/pathology , Muscle Neoplasms/congenital , Muscle Neoplasms/pathology , Biopsy, Needle , Female , Follow-Up Studies , Hamartoma/surgery , Humans , Hyperpigmentation/diagnosis , Hyperpigmentation/etiology , Immunohistochemistry , Infant, Newborn , Muscle Neoplasms/surgery , Muscle, Smooth/pathology , Photomicrography , Rare Diseases , Risk Assessment , Treatment OutcomeSubject(s)
Leukemia, Myeloid, Acute/diagnosis , Sarcoma, Myeloid/diagnosis , Anemia/etiology , Humans , Male , Middle AgedSubject(s)
Nevus, Pigmented/diagnosis , Arm , Child , Diagnosis, Differential , Disease Progression , Humans , Male , Nevus, Pigmented/pathologyABSTRACT
A middle-aged HIV infected man receiving treatment for pulmonary tuberculosis, presented with a febrile illness along with evanescent, erythematous nodular lesions all over the body. On examination, he had features suggestive of lepromatous leprosy with lesions of erythema nodosum leprosum. In addition, there were multiple small, circumscribed areas of slack skin, clinically and histopathologically suggestive of anetoderma. Both leprosy and HIV infection are known to give rise to lesions of anetoderma. Pathogenesis of anetoderma in these infectious conditions is discussed.
Subject(s)
HIV Infections/complications , Leprosy, Lepromatous/diagnosis , Skin Diseases, Vesiculobullous/diagnosis , Tuberculosis, Pulmonary/complications , Adult , Diagnosis, Differential , Humans , Leprosy, Lepromatous/complications , Leprosy, Lepromatous/pathology , Male , Skin Diseases, Vesiculobullous/complications , Skin Diseases, Vesiculobullous/pathologyABSTRACT
A 14-year-old girl with diffuse palmoplantar keratoderma with hyperhidrosis and progressive extension of keratoderma to the dorsum of the hands and feet is reported. The inheritance pattern was autosomal dominant.
ABSTRACT
An elderly man with a long history of smoking presented with an excruciatingly painful mass of short duration on the left side of the neck, without any systemic complaint. Clinical and radiological examination revealed left upper lobe consolidation which was proved to be secondary to bronchogenic carcinoma. Histopathological findings from a skin biopsy from the neck mass were consistent with inflammatory cutaneous metastasis. Interestingly, this was the presenting feature of the underlying malignancy in this patient. This pattern of cutaneous metastasis has rarely been reported in association with bronchogenic carcinoma.
ABSTRACT
Many clinical variants of lichen nitidus (LN) have been reported. We describe two children with distribution of LN lesions on sun exposed areas with typical histological features of LN. We propose to add actinic LN as another clinical variant.
ABSTRACT
A 20-year-old male patient with vitiligo who developed psoriasis is reported here. There was co-existence of both diseases and co-habitation lesions at places. Clinical heterogenicity of both diseases and new conclusions are discussed.
ABSTRACT
A 60-year old male with papulo erythroderma of Ofuji is presented here for its rarity. The characteristic 'deck chair' sign was present. Response to PUVA therapy was noted.
