ABSTRACT
VISUAL ABSTRACT: http://links.lww.com/EJA/A927.
Subject(s)
Cardiac Surgical Procedures , Humans , Prospective Studies , Cardiac Surgical Procedures/adverse effects , Male , Aged , Female , Anesthesia, Conduction/methods , Emergence Delirium/prevention & control , Emergence Delirium/etiology , Emergence Delirium/diagnosis , Emergence Delirium/epidemiology , Middle Aged , Preoperative Care/methods , Postoperative Complications/etiology , Postoperative Complications/prevention & control , Delirium/etiology , Delirium/prevention & control , Delirium/diagnosisABSTRACT
BACKGROUND: Health-related quality of life (HRQOL) is an increasingly important issue in assessing the consequences of any surgical or medical intervention. Our study aimed to evaluate change in HRQOL 6 months after elective cardiac operations and to identify specific predictors of poor HRQOL. METHODS: In this prospective, single-center study, HRQOL was evaluated before and 6 months after the operation using the Medical Outcome Study 36-Item Short Form Health Survey questionnaire and its two components: the Physical Component Summary and the Mental Component Summary. We distinguished patients with worsening of HRQOL according to the minimal clinically important difference. All consecutive adult patients undergoing cardiac operations were included. RESULTS: The preoperative and postoperative 36-Item Short Form Health Survey questionnaires were completed by 326 patients, and 24 patients died before completing follow-up questionnaires. On the basis of the definition used, clinically significant deterioration of HRQOL was observed in 93 patients (26.6%) for the Physical Component Summary and in 99 patients (28.2%) for the Mental Component Summary. Renal replacement for acute renal failure and mechanical ventilation for longer than 48 hours were independent risk factors for Physical Component Summary and Mental Component Summary worsening or death. CONCLUSIONS: Although our study showed overall improvement of quality of life after cardiac operations, more than one-quarter of the patients manifested deterioration of HRQOL at 6 months postoperatively. The findings from this study should help clinicians to inform patients about their likely postoperative functional status and quality of life.
Subject(s)
Cardiac Surgical Procedures/methods , Cardiac Surgical Procedures/psychology , Minimal Clinically Important Difference , Quality of Life , Surveys and Questionnaires , Academic Medical Centers , Adult , Aged , Cardiac Surgical Procedures/adverse effects , Disease Progression , Elective Surgical Procedures/adverse effects , Elective Surgical Procedures/methods , Female , Follow-Up Studies , France , Humans , Logistic Models , Male , Middle Aged , Multivariate Analysis , Postoperative Complications/physiopathology , Postoperative Complications/surgery , Prospective Studies , Recurrence , Risk Assessment , Time FactorsABSTRACT
The aim of this study was to evaluate the effect of gamma radiation processing of millet grains on fungal incidence, germination, free fatty acids content, protein solubility, digestible protein, and antinutritional factors (tannin and phytic acid). The grains were exposed to gamma radiation at doses 0.25, 0.5, 0.75, 1.0, and 2.0 kGy. Obtained results revealed that radiation of millet grains at a dose level higher than 0.5 kGy caused significant (P < 0.05) reduction on the percentage of fungal incidence and the free fatty acid of the seeds, while, no significant change in the germination capacity was observed of the grains after radiation. Additionally, the radiation process caused significant (P < 0.05) reduction on both tannins and phytic acid content and gradual increment on in vitro protein digestibility of the grains. On the other hand, the treatments significantly (P < 0.05) increased the protein solubility of the grains. Obtained results indicate that gamma irradiation might improve the quality characteristics of millet grains, and can be used as a postharvest method for disinfestations and decontamination of millet grains.
