Does fear of activity predict exercise capacity in patients with coronary artery disease in both sexes? A cross-sectional multicenter study.

Objectives: This study aimed to identify whether fear of activity predicts exercise capacity in patients with coronary artery disease (CAD) and whether there is a difference between sexes regarding this relationship. Patients and methods: One hundred ninety-seven patients (145 males, 52 females; mean age: 56.3±10.8 years; range, 22 to 80 years) with a diagnosis of CAD or cardiac event in the previous one to 60 months were enrolled in this cross-sectional multicenter study between November 2015 and February 2017. Demographic and clinical features were recorded. Fear of activity was assessed by the fear of activity scale in patients with CAD (FactCAD). A 6-min walk test was used to assess exercise capacity. Results: Female participants were older, less educated, and less employed (p=0.045, p=0.048, and p<0.001, respectively) than males. Prevalence of myocardial infarction was higher in males. Comorbidities were higher in females. Multiple linear regression predicted 6-min walk distance (6MWD) based on FactCAD, sex, and education level with an r-squared of 0.321 (p<0.001). Fear of activity had an effect on walking distance in males (each additional score of FactCAD predicts a decrease of 1.3 m in 6MWD), together with disease duration, presence of chronic pulmonary disease, and low back pain, whereas fear of activity was not a predicting factor on walking distance in females. Age, education, and presence of angina predicted 6MWD in females. Conclusion: This study emphasizes that fear of activity is one of the predictors of 6MWD in males with CAD, and its assessment is recommended as a possible barrier to rehabilitation.

Comparison of the effectiveness of anti-gravity treadmill exercises and underwater walking exercises on cardiorespiratory fitness, functional capacity and balance in stroke patients.

INTRODUCTION: Aerobic exercise training after stroke has positive effects on quality of life, motor recovery, and aerobic endurance. The aim of this study was to investigate the effectiveness of anti-gravity treadmill gait training and underwater walking therapy on cardiorespiratory fitness, gait and balance in stroke survivors. METHODS: The study included 39 patients with a history of stroke who were admitted to our center between July 2017 and January 2018. The patients were randomly assigned to anti-gravity treadmill training, underwater walking therapy, or a control group. The aerobic capacity of the participants was evaluated with the 6-min walk test and cycle ergometer testing before and after the treatment. Balance was examined using the Berg Balance Scale (BBS). RESULTS: There was a statistically significant increase from pre- to post-treatment with regard to maximum heart rate and length of walking distance during 6-min walk test parameters in patients who underwent anti-gravity treadmill training (p < 0.05). The cycle ergometer training results showed significant improvements compared to baseline after treatment in patients who underwent anti-gravity training in terms of maximum heart rate attained during exercise stress testing, time to complete the test, rates of metabolic equivalents of task scores and peak oxygen consumption (p < 0.05). Improvements were also observed in ventricular repolarization indices including corrected QT intervals (QTc), Tp-e interval and Tp-e/QT, Tp-e/QTc ratio in the anti-gravity group (p < 0.05). BBS results showed no statistically significant difference in all groups (p > 0.05). CONCLUSION: The data of this study showed that anti-gravity treadmill training has favorable effects on cardiorespiratory fitness in stroke survivors.

Validity and reliability of Turkish transcultural adaptation of the Prosthetic Limb Users Survey of Mobility.

BACKGROUND: Amputee-specific, self-assessment mobility scales are essential to evaluate mobility in lower-limb amputees. OBJECTIVES: To evaluate the validity and reliability of a Turkish translation and adaptation of the Prosthetic Limb Users Survey of Mobility. STUDY DESIGN: This is a validation study. METHODS: Turkish translation of the Prosthetic Limb Users Survey of Mobility (PLUS-M-T) from its original was performed following the rules of intercultural adaptation and translation methods. The PLUS-M-T and its 12-item short form were applied to '100 induviduals with limb loss twice in 3-day intervals. The structural validity analysis was determined by calculating the correlation with the Amputee Mobility Scale, which is a valid, reliable scale for assessing the functional level in amputees. The Cronbach alpha coefficient was calculated to analyze the internal consistency. The interclass correlation coefficient (ICC) and Spearman correlation coefficient (r) were calculated, and the test-retest reliability was determined. RESULTS: A positive, high correlation was found between the first application and its repetition of both PLUS-M-T (ICC = 0.85, r = 0.94, P < 0.001) and 12-item short form (ICC = 0.92, r = 0.93, P < 0.001). The internal consistency was high for both PLUS-M-T (Cronbach alpha = 0.94) and 12-item short form (Cronbach alpha = 0.91). A positive, high correlation was found between the scores obtained from the Amputee Mobility Scale and PLUS-M-T (r = 0.84, P < 0.001) and 12 question short form (r = 0.77, P < 0.001). CONCLUSION: Turkish translation of the PLUS-M questionnaire is a valid and reliable scale for assessing the mobility of individuals who have undergone lower-extremity amputation using a prosthesis.

The use of myoelectric prosthesis in a sample of veterans with unilateral upper extremity amputation: prosthesis satisfaction and quality of life.

AIMS: To determine the relationship between clinic and prosthesis-related characteristics and psychosocial adjustment, activity restriction, satisfaction with the prosthesis and quality of life in myoelectric prosthesis users with upper limb amputation. METHODS: Thirty patients with myoelectric prosthesis users with upper limb amputation took part in this study. The patients' demographic and clinical information were recorded. Psychosocial adjustment, activity restriction and satisfaction with the prosthesis were assessed with Trinity Amputation and Prosthesis Experience Scales-Revised (TAPES-R). Short-Form 36 (SF-36) was used for the quality of life. RESULTS: TAPES-R activity restriction score was significantly higher in patients with transhumeral or elbow disarticulation and with concomitant lower limb amputation (p = 0.009, p = 0.037, respectively). TAPES-R psychosocial adjustment subparameter score had significantly moderate correlation with daily prosthesis wearing time (p = 0.019 r = 0.425). A significant negative correlation was found between age at the time of the injury and SF-36 role limitation due to physical problem (p = 0.028 r = - 0.401). CONCLUSIONS: Clarifying the factors related to psychosocial adjustment, activity restriction, prosthesis satisfaction and quality of life in individuals with upper extremity amputation and producing interventions/approaches that support patients' life are meaningful and important steps. CLINICAL TRIAL REGISTER: E2-22-1416.

Lower limb prosthetic prescription.

Lower limb amputations are the most common level of amputation. Mobilization of patients with lower limb amputations is an important rehabilitation goal. It is critical to prescribe the most appropriate prosthesis for the patient to achieve the rehabilitation goal in lower extremity amputations. Appropriate prosthesis prescription in lower extremity amputations is based on the selection of the correct prosthetic parts. The choice of prosthesis should be based on the patient's activity level and potential. The prosthesis decision should be made by a team, particularly with the participation of the patient.

Assessment of isokinetic hip muscle strength and predictors in patients with lower limb amputation: A cross-sectional study.

Objectives: The purpose of the study was to determine isokinetic features and analyze significant predictors related to activity level of patients with lower limb amputation. Patients and methods: Forty-three male patients (mean age: 32.9±8.8 years; range, 21 to 50 years) with lower limb amputation were recruited consecutively for this cross-sectional study between March 1, 2022, and June 30, 2022. The hip flexor and extensor peak torques and total work were evaluated by an isokinetic dynamometer. The secondary outcome measure was the Amputee Mobility Predictor. A linear regression analysis was used to determine factors independently affecting Amputee Mobility Predictor scores. Results: All data of patients with unilateral amputation, except for flexor (p=0.285) and extensor (p=0.247) peak torques on the dominant side, were higher than those of patients with amputation. Dominant side extensor peak torque was statistically higher than nondominant side extensor peak torque (59.4±30.7 vs. 43.4±32.0) in patients with bilateral amputation. No difference was detected between amputated and intact sides of patients with unilateral amputation. Both flexor and extensor total work on the amputated side of the patients with below-knee amputation were higher than the patients with above-knee amputations (63.5±21.1 vs. 94.1±34.3 and 67.1±34.0 vs. 113.0±51.5, respectively). Unilateral amputation (odds ratio: 7.442) and nondominant side extensor total work (odds ratio: 0.615) were found to be significant predictors related with amputee mobility predictor scale. Conclusion: It is possible to have an idea about the possible activity level of the patients with lower limb amputation with the help of the predictors obtained in the current study.

Kinesiophobia and associated factors in patients with traumatic lower extremity amputation.

Objectives: The study aimed to demonstrate the level of kinesiophobia in patients with traumatic lower limb amputation (LLA) and to investigate the correlation between kinesiophobia and associated factors. Patients and methods: This cross-sectional study included 52 male patients (mean age: 37.8±8.7 years; range, 18 to 65 years) with traumatic LLA between March 2021 and July 2021. Kinesiophobia level was measured with the Tampa Scale for Kinesiophobia. Pain intensity and prosthesis satisfaction were evaluated with the Visual Analog Scale. The Falls Efficacy Scale-International was used for the assessment of fear of falling. The Nottingham Health Profile was used to evaluate the quality of life. Results: The percentage of the patients with a high level of kinesiophobia was 40.4%. Kinesiophobia was significantly correlated with residual limp pain intensity (r=0.317, p=0.022), the number of falls (r=0.284, p=0.041), fear of falling (r=0.495, p=0.001), and quality of life (r=0.512, p=0.001). No significant correlations between kinesiophobia and intact limb pain intensity, low back pain intensity, or prosthesis satisfaction were detected. Regression analysis showed that the physical activity subscale score of the Nottingham Health Profile was a statistically significant predictor of high kinesiophobia scores. Conclusion: The findings suggest that limitations in physical activity were independently associated with kinesiophobia in patients with traumatic LLA. Fear and avoidance behaviors, which may limit physical activity, should be considered in the evaluation of individuals with LLA.

A comparison of two different prosthetic feet on functional capacity, pain severity, satisfaction level and quality of life in high activity patients with unilateral traumatic transtibial amputation.

AIM: Prescribing optimal prosthetic feet to ensure successful rehabilitation is difficult since there are no generally established clinical guidelines based on objective data. The aim of the study was to compare functional capacity, pain intensity, satisfaction level and quality of life (QoL) of high activity patients with unilateral transtibial amputation using non-articulated carbon foot (non-articulating ankle, NAA) with those of using carbon foot with hydraulic ankle (articulating hydraulic ankle, AHA). METHODS: Forty-two patients (21 with NAA and 21 with AHA) with unilateral transtibial traumatic amputation from tertiary rehabilitation center were participated in this cross-sectional study. Outcome measures were six-minute walking test (6MWT), Visual Analogue Scale (VAS) and the Short Form-36 (SF-36). The level of difficulty experienced during ambulating on different terrains was recorded on a 5-point Likert scale. RESULTS: There were no significant statistical differences in 6MWT, pain intensity, prosthetic foot satisfaction level and QoL between the two groups. The level of difficulty experienced during descending ramps was higher in the NAA group than in the AHA group (p = 0.016). The most common reason for dissatisfaction were inflexibility for the NAA group (14.3%), frequent dysfunction for the AHA group (28.6%). CONCLUSION: Our results showed that the level of difficulty experienced during descending ramps was higher in the NAA group than in the AHA group. Further studies with larger sample sizes are needed comparing microprocessor AHAs with NAA and AHA.

Assessment of lower limb peripheral nerves with ultrasound in patients with traumatic amputation.

OBJECTIVES: This study aims to assess the sciatic nerve (SN), common peroneal nerve (CPN), and tibial nerve (TN) by ultrasound in patients with traumatic lower limb amputation (LLA) and to examine the possible relationship between ultrasonographic and clinical findings. PATIENTS AND METHODS: This cross-sectional study included a total of 33 male patients (mean age: 36.6±8.7 years; range, 21 to 48 years) who had LLA due to traumatic injury between May 2019 and April 2020. Amputation and prosthesis use and functional K level of activity were recorded. Ultrasound examinations were performed to measure the cross-sectional areas (CSAs) of the SN, CPN, and TN bilaterally at the same levels. The values from the normal sides were accepted as controls. RESULTS: The CSA values were greater on the amputated sides than the non-amputated sides for SN (p=0.001), TN (p=0.001), and CPN (p=0.015), regardless of the activity level. The amputated side SN (p=0.001), TN (p=0.001), and CPN (p=0.016) were thicker in patients with level of K4 activity than the non-amputated side. For the patients with K3 activity level, larger TN CSA values were determined on the amputated side, compared to those at the K4 level (p=0.035). The SN was found to be greater in patients using microprocessor-controlled knee prosthesis (p=0.032) and TN was larger in hypobaric sealing membrane users on the amputated sides (p=0.041). CONCLUSION: The SN, CPN, and TN were found to be larger in all patients on the amputated sides and in patients with K4 activity level. Based on these findings, the K3 activity level and the use of hypobaric sealing membrane seems to affect the CSA values of TN. Additionally, the use of microprocessor knee prosthesis affects the CSA values of SN. We believe that these results may be essential for the analysis or prediction of lower extremity nerve involvement according to the K activity level and the use of prosthesis in patients with traumatic LLA.

Gülhane lower extremity amputee rehabilitation protocol: A nationwide, 123-year experience.

Amputation, one of the oldest known surgical procedures, causes many physical, mental and sociological problems. With its 123 years of experience, Gülhane has a special knowledge and experience, particularly in amputation. The main purpose of this protocol is to reveal the steps to be followed in individuals with lower extremity amputation. In this way, it is aimed to create a resource which can be used by our colleagues who have difficulties in using an appropriate approach due to the lack of experience.

Ultrasound Findings of Young and Traumatic Amputees With Lower Extremity Residual Limb Pain in Turkey.

OBJECTIVE: The current study was designed to document clinical and ultrasound (US) findings of patients with residual limb pain (RLP) after amputation and to investigate the relationship between these findings. MATERIALS AND METHODS: A chart review was performed to identify demographic and clinical data including the age (current and at the time of injury), time since amputation, gender, reason for amputation, affected limb number, side and level of limb loss, and ultrasonographic findings of young and traumatic amputees with RLP. RESULTS: The study included a total of 147 patients. Inflammation and neuroma were the leading pathologies in 20-29 years and 30-39 years age groups, respectively. Inflammation/edema were detected significantly more in patients with <1 year since amputation (P = 0.001). Neuroma was found at a significantly high rate in patients at 1-5 years (P = 0.029) and infection/abscess was more common in patients at >5 years since amputation (P = 0.051). The percentage of neuromas in below-the-knee amputees was significantly higher than in non-below-the-knee amputees (45.8% vs. 28.6%). Neuroma formation was detected in 50% of the patients with land mine-related amputation and at 27% in patients with amputation secondary to other traumatic reasons. Regression analysis showed below-the-knee-level amputation to be an associated factor for US abnormality. CONCLUSION: The leading US findings were inflammation/edema, neuroma, and infection/abscess in traumatic amputees with RLP. The US findings might be different in patients according to the time since amputation. Patient with land mine-related amputations may have different US findings.

A case of recurrent complex regional pain syndrome accompanying Raynaud's disease: a prospective coincidence?

Complex regional pain syndrome (CPRS) and Raynaud's disease are disorders characterized by vasomotor disturbances associating with abnormal autonomic nervous system. We present a case of CRPS involving a history of recurrence and no initiating event. Raynaud's disease accompanying CRPS was diagnosed clinically in the patient. We propose that a sympathetic dysfunction underlies the pathophysiologies of both disorders and may be responsible for the coexistence of these two distinct entities. Recurrence and unknown etiology of CRPS might account for temporary alterations in sympathetic function.

Behcet's disease presenting with sudden-onset paraplegia due to anterior spinal artery involvement: 1-year follow-up of rehabilitation in conjunction with medication.

A 26-year-old male patient with sudden-onset paraplegia was presented. Clinical and imaging evaluation revealed isolated spinal cord lesions at thoracal levels and anterior spinal arterial involvement. Diagnosis of Behcet's disease was established with associating clinical findings with medical history. Vigorous medication and rehabilitation program were performed. Through the 1-year rehabilitation period in conjunction with medication, strength and functions improved gradually. A satisfactory functional gain as a rehabilitative goal in independence in activities of daily living and long-distance ambulation achieved around 4 months. The patient reached full independence after 1-year. As conclusion, Behcet's disease can present with sudden-onset paraplegia. In case of no evident etiology for paraplegia in young male, neuro-Behcet's disease also should be kept in mind. Contrary to assumption, early aggressive treatment and continuous rehabilitation in conjunction with medication might provide good prognosis with excellent clinical outcome in spinal cord involvement. Satisfactory functional recovery should be expected only after 3-4 months, and complete independence can be achieved after 1 year.

Accuracy of ultrasound-guided suprascapular nerve block measured with neurostimulation.

Although the use of ultrasound (US) to perform suprascapular nerve block (SsNB) is rapidly gaining popularity, information about its accuracy is still lacking. The aim of this study was to investigate the proximity of the needle to suprascapular nerve under US guidance by means of neurostimulation current intensity in SsNB. The patients who were referred for SSnB due to shoulder pain were included in the study. The patients were placed in sitting position, and when the operator decided that the needle was in the correct place under US guidance, the time duration until that time and the current amplitude in that location were recorded. Current intensity was obtained by gradually increasing the amplitude until patient feels parestesia over the shoulder area or contractions of the supraspinatus or infraspinatus muscles. Out of 27 patients, in five patients current intensity was between 0.1 and 0.8 mA (successful) and time duration was 2.52 ± 1.67 min in this group; in 19 patients, current intensity was between 0.9 and 1.4 mA (semi-successful) and time duration was 1.86 ± 1.02 min in this group; in three patients, current intensity was ≥ 1.5 mA (unsuccessful) and time duration was 2.41 ± 1.02 min in this group. Our results show that the needle could not reach sufficient proximity to the suprascapular nerve with only US guidance by means of NS current intensity.

The effects of electrical stimulation combined with continuous passive motion versus isometric exercise on symptoms, functional capacity, quality of life and balance in knee osteoarthritis: randomized clinical trial.

The aim of this study was to evaluate effects of electrical stimulation combined with continuous passive motion (CPM-ES) versus isometric exercise on symptoms, functional capacity, quality of life, muscle strength, knee and thigh circle measurements, and balance in knee osteoarthritis (OA). This is a randomized clinical trial. The study was done in Gulhane Military Medical Academy (GMMA) Rehabilitation Center. Forty patients with knee OA were included in this study. Participants were randomly assigned to two groups: 20 patients placed in Group 1 were treated with conventional physical therapy and CPM-ES combination; 20 patients in Group 2 were treated with conventional physical therapy and isometric exercise. Therapies were applied 3 weeks, 5 days per week. The following main outcome measures were done: values of pain (VAS was used), WOMAC, SF-36, knee and thigh circle measurements, isokinetic tests, dynamic and static balance tests were determined at baseline and after the treatment. There were no statistically significant differences in the tested variables between the groups for post-treatment values. Dynamic and static balance test improved statistically strongly significantly in both groups. The findings of this study demonstrate that knee OA patients could improve their balance function in both static and dynamic conditions after CPM-ES combination or isometric exercise therapy. The improvement might prevent knee OA patients from falling down and increase their sense of security during physical activities.