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Clin. transl. oncol. (Print) ; 10(11): 764-767, nov. 2008. ilus
Article in English | IBECS | ID: ibc-123553

ABSTRACT

Oxaliplatin has been approved for adjuvant treatment of colorectal cancer. Toxicity induced by oxaliplatin is moderate and manageable, but some isolated cases of severe pulmonary toxicity associated to oxaliplatin have been reported. Two fatal cases of interstitial pneumonitis rapidly evolving to pulmonary fibrosis are reported here (AU)


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Subject(s)
Humans , Male , Female , Aged , Pulmonary Fibrosis/chemically induced , Organoplatinum Compounds/adverse effects , Lung Diseases, Interstitial/chemically induced , Antineoplastic Agents, Alkylating/adverse effects , Lung Neoplasms/drug therapy , Lung Neoplasms/secondary , Pulmonary Fibrosis/pathology , Pulmonary Fibrosis , Organoplatinum Compounds/administration & dosage , Lung Diseases, Interstitial/pathology , Lung Diseases, Interstitial , Combined Modality Therapy/methods , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Fluorouracil/therapeutic use
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