1.
Bioorg Med Chem Lett
; 19(19): 5760-3, 2009 Oct 01.
Article
in English
| MEDLINE
| ID: mdl-19703773
ABSTRACT
A new class of selective MMP-12 inhibitors have been identified via high throughput screening. Crystallization with MMP-12 confirmed the mode of binding and allowed initial optimization to be carried out using classical structure based design.