Effect of LED photobiomodulation on dental implant osseointegration: An in vivo study.

Background: Photobiomodulation (PBM) may be prescribed after dental surgery to accelerate tissue healing and improve implant stability. The objective of this study is to evaluate the efficiency of LED-PBM on the dental implant osseointegration. Methods: A total of 48 implants (KontactTM) were inserted in 8 Yucatan minipigs (6 implants per minipig) divided into 2 groups (test and control). The test group received LED-PBM with a total energy of 124.2 J/cm2 delivered over 4 sessions (at day0, day+8, day+15 and day+28) lasting 12 minutes each. At day+28, all animals were sacrificed, and their mandibles removed to perform histologic and histomorphometric analysis. Implant osseointegration was evaluated using the computation of bone/implant contact (BIC) index and bone surface/total surface (BS/ TS) ratio. The groups were compared using Student's unpaired t test. Results: BIC index and BS/TS ratio were significantly higher within the test group as compared to the control group (P<0.01). Histologic observations on bone tissues demonstrated that LED-PBM may improve and accelerate dental implant osseointegration: 25% of dental implants analyzed within the test group were completely osseointegrated, versus 12.5% within the control group. Conclusion: This experimental study indicates that LED-PBM contributes to enhancing implant treatment outcomes.

Experimental analysis and numerical fatigue life prediction of 3D-Printed osteosynthesis plates.

The trend towards patient-specific medical orthopedic prostheses has led to an increased use of 3D-printed surgical implants made of Ti6Al4V. However, uncertainties arise due to varying printing parameters, particularly with regards to the fatigue limit. This necessitates time-consuming and costly experimental validation before they can be safely used on patients. To address this issue, this study aimed to employ a stress-life fatigue analysis approach coupled with a finite element (FE) simulation to estimate numerically the fatigue limit and location of failure for 3D-printed surgical osteosynthesis plates and to validate the results experimentally. However, predicting the fatigue life of 3D components is not a new concept and has previously been implemented in the medical device field, though without experimental validation. Then, an experimental fatigue test was conducted using a proposed modification to the staircase method introduced in ISO 12107. Additionally, a FE model was developed to estimate the stress cycles on the plate. The stress versus number of cycles to failure curve (S-N) obtained from the minimum mechanical properties of 3D-printed Ti6AI4V alloy according to ASTM F3001-14 to predict the fatigue limit. The comparison between experimental results and fatigue numerical predictions showed very good agreement. It was found that a linear elastic FE model was sufficient to estimate the fatigue limit, while an elastic-plastic model led to an accurate prediction throughout the implant's cyclic life. The proposed method has great potential for enhancing patient-specific implant designs without the need for time-consuming and costly experimental regulatory testing.

Implant-supported overdentures with different clinical configurations: Mechanical resistance using a numerical approach.

STATEMENT OF PROBLEM: Implant-supported overdentures (IODs) are a treatment option for patients with complete edentulism. However, this treatment increases the possibilities of peri-implant complications, characterized by inflammation or partial loss of surrounding hard and soft tissues. PURPOSE: The purpose of this finite element analysis study was to evaluate the mechanical performance of different bar-IOD designs under different clinical configurations by comparing the stress and strain distribution on the bone during secondary stabilization. MATERIAL AND METHODS: A finite element model of the mandible representing a patient with complete edentulism was developed. Different designs of bar-IODs were modeled and compared. The parameters studied were the material properties (cobalt-chromium, zirconium dioxide, titanium grade 5, and titanium grade 4), diameter and bar-IOD cross-sectional shape, tilt of the posterior implants (30 degrees), presence of a distal extension cantilever in the bar-IODs (12 mm), and number of implants (4 or 6). Two different mastication loading conditions were analyzed. One- and 2-way ANOVAs and the Tukey honestly significant differences post hoc test (α=.05) were used to determine the significant von Mises stress and strain values in the bone. RESULTS: The 4 materials tested in the bar-IOD did not have a significant mechanical effect on the bone (P<.05). A smaller diameter and structure of the bar-IOD led to significantly higher bone stress (P<.001). A distal extension cantilever led to an increased stress concentration (model M1 versus model M3: P<.001), which reached 50% in the event of tilting of the posterior implants (model M2 versus model M4: P<.001). Tilting of the posterior implants alone, without extension, had a nonsignificant effect (model M3 versus model M4: P=.999). Model M5 supported with 6 implants reduces the stress transferred to the bone compared with model M3 supported with 4 implants (P<.05). CONCLUSIONS: Distal extensions in bar-IODs, the tilt of the posterior implants, and the low amount of material in the cross-sectional area in the bar-IOD were the most influential parameters on the mechanical resistance of dental implants in the mandibular bone.

Mechanical strength and fracture point of a dental implant under certification conditions: A numerical approach by finite element analysis.

STATEMENT OF PROBLEM: Implant prosthodontics provides high-quality outcomes thanks to recent technological developments and certification procedures such as International Organization for Standardization (ISO) 14801. However, these certification tests are costly, and the result is highly uncertain as the influence of design variables (materials and structure) is still unknown. The design process could be significantly improved if the influence of design parameters were identified. PURPOSE: The purpose of this in vitro study was to use finite element analysis (FEA) to assess the influence of design parameters on the mechanical performance of an implant in regard to testing conditions of ISO 14801 standard. MATERIAL AND METHODS: An endosseous dental implant was loaded under ISO 14801 testing conditions by numerical simulation, with 4 parameters evaluated under the following conditions: conditions of the contact surface area between the implant and the loading tool, length of the fixation screw, implant embedding depth, and material used for implant stiffness. FEA was used to compare the force that needed to reach the implant's yield and fracture strength. RESULTS: A dental implant's fracture point can be increased by 41% by improving the contact surface area, by 20% depending on the type of material, by 4% depending on the length of the fixation screw, and by 1.4% by changing the implant embedding depth. CONCLUSIONS: FEA made it possible to evaluate 4 performance parameters of a dental implant under ISO 14801 conditions. Under these conditions, the contact surface area was found to be the major parameter influencing implant performance. This observation was validated experimentally in a fatigue test under ISO 14801 conditions.