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1.
Article in English | MEDLINE | ID: mdl-27981038

ABSTRACT

[This corrects the article on p. 1 in vol. 6, PMID: 26870699.].

2.
Article in English | MEDLINE | ID: mdl-26870699

ABSTRACT

Hantaan virus (HTNV) causes hemorrhagic fever with renal syndrome (HFRS), which is a zoonosis endemic in eastern Asia, especially in China. The reservoir host of HTNV is field mouse (Apodemus agraricus). The main manifestation of HFRS, including acute kidney injury, increases vascular permeability, and coagulation abnormalities. In this paper, we review the current knowledge of the pathogenesis of HFRS including virus factor, immunity factor and host genetic factors. Furthermore, the treatment and prevention will be discussed.


Subject(s)
Hantaan virus/immunology , Hemorrhagic Fever with Renal Syndrome/pathology , Host-Pathogen Interactions/immunology , Immunity, Cellular/immunology , Immunity, Innate/immunology , Antibodies, Viral , Antiviral Agents/therapeutic use , Asia , Endothelial Cells/pathology , Endothelial Cells/virology , Europe , Hemorrhagic Fever with Renal Syndrome/drug therapy , Hemorrhagic Fever with Renal Syndrome/transmission , Hemorrhagic Fever with Renal Syndrome/virology , Humans , Kidney/pathology , Kidney/virology
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