Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 2 de 2
Filter
Add more filters










Database
Language
Publication year range
1.
Article in English | MEDLINE | ID: mdl-38350230

ABSTRACT

Ocular trauma is an important cause of monocular blindness worldwide. Injury to the lens after blunt or penetrating trauma is common and can result in vision impairment. Selecting the most appropriate therapeutic approaches depend on factors such as the patients' age, mechanism of trauma, and underlying clinical conditions. Early management, especially within childhood, is essential due to the difficulties involved in examination, anatomical variations, as well as accompanying intraocular inflammation, amblyopia, or vitreoretinal adhesions. The objective of this paper is to provide a comprehensive review of the epidemiology and clinical management of traumatic cataract, highlighting the significance of accurate diagnosis and the selection of the optimal therapeutic approach.

2.
Surv Ophthalmol ; 69(2): 211-223, 2024.
Article in English | MEDLINE | ID: mdl-37944600

ABSTRACT

Polyvinyl pyrrolidone or povidone-iodine (PVP-I) is a water-soluble complex formed by the combination of iodine and a water-soluble polymer, polyvinyl pyrrolidone. This complex exerts bactericidal, fungicidal, and virucidal action by gradually releasing free iodine at the site of application to react with pathogens. In ophthalmology, PVP-I is used as a disinfectant and antiseptic agent for preoperative preparation of the skin and mucous membranes and for treating contaminated wounds. PVP-I has been shown to reduce effectively the risk of endophthalmitis in various ocular procedures, including cataract surgery and intravitreal injections; however, it has also been used in the treatment of conjunctivitis, keratitis, and endophthalmitis, with promising results especially in low-resource situations. PVP-I has been associated with complications such as postoperative eye pain, persistent corneal epithelial defects, ocular inflammation, and an attendant risk of keratitis. In cases of poor PVP-I tolerance, applying PVP-I at lower concentrations or using alternative antiseptics such as chlorhexidine should be considered. We provide an update on the efficacy of PVP-I in the prophylaxis and treatment of conjunctivitis, keratitis, and endophthalmitis and a comprehensive analysis of the current literature regarding the use of PVP-I in the management of these ocular conditions. Also, PVP-I-related adverse effects and toxicities and its alternatives are discussed. The goal is to present a thorough evaluation of the available evidence and to offer practical recommendations for clinicians regarding the therapeutic usage of PVP-I in ophthalmology.


Subject(s)
Anti-Infective Agents, Local , Cataract Extraction , Conjunctivitis , Endophthalmitis , Iodine , Keratitis , Ophthalmology , Humans , Povidone-Iodine/pharmacology , Povidone-Iodine/therapeutic use , Polyvinyls , Anti-Infective Agents, Local/pharmacology , Anti-Infective Agents, Local/therapeutic use , Iodine/therapeutic use , Endophthalmitis/drug therapy , Endophthalmitis/prevention & control , Povidone , Conjunctivitis/chemically induced , Conjunctivitis/drug therapy , Keratitis/drug therapy , Water
SELECTION OF CITATIONS
SEARCH DETAIL
...