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1.
Cell Stress Chaperones ; 25(3): 559-561, 2020 05.
Article in English | MEDLINE | ID: mdl-32180126

ABSTRACT

Due to an unfortunate misunderstanding, the top part of Figures 2 and 3 are not correctly displayed. The original article has been corrected and the proper version of Figures 2 and 3 is also published here.

2.
Cell Stress Chaperones ; 25(3): 549-558, 2020 05.
Article in English | MEDLINE | ID: mdl-31970694

ABSTRACT

Astaxanthin is a powerful carotenoid antioxidant prevalent in marine organisms and approved as a food supplement. Recent studies have demonstrated Astaxanthin's beneficial attributes in various health states. Following initial reports of potential heat protective properties in Astaxanthin supplemented rats, we present here results of a novel study examining the effect of Astaxanthin supplementation on the heat shock response in rats in relation to core temperature (Tc) and the ensuing physiological strain. Two hours of heat stress at 41 °C during which rats developed their thermoregulatory hyperthermic plateau resulted in progressive increases in HSP72 and HSP27 in the Astaxanthin (Oleoresin)-treated group but not in the control (Olive oil) group. Enhanced elevation in HSPs suggests that Astaxanthin supplementation may augment the cellular stress protective response to heat stress.


Subject(s)
Heat-Shock Proteins/metabolism , Heat-Shock Response/drug effects , Animals , Liver/metabolism , Male , Myocardium/metabolism , Rats, Sprague-Dawley , Xanthophylls/pharmacology
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