[Assessment of the health status of children born as a result of extracorporeal fertilization and artificial insemination]. / Otsenka sostoianiia zdorov'ia detei, rozhdennykh v rezul'tate ékstrakorporal'nogo oplodotvoreniia i iskusstvennoi inseminatsii.

Comprehensive assessment of the health status of 142 children born In Research Center of Obstetrics, Gynecology, and Perinatology, Russian Academy of Medical Sciences, showed that 92% of children not only survived, but were healthy and their neuropsychic development was normal for age. The hormonal and immunity status was virtually normal. The authors come to a conclusion that extracorporeal fertilization and artificial insemination in the treatment of a sterile marriage are Justified and effective. The health status of the children who are born is normal, provided certain indications are adhered to.

[Neonatal neurology: the reality, illusions and hopes]. / Neonatal'naia nevrologiia: deistvitel'nost', illiuzii i nadezhdy.

Discusses the status of neurologic care of the newborns and the significance of the routine and present-day diagnostic methods. Suggests new forms of organizing the neurologic care within the frames of local perinatal centers.

[The procedures of a neonatal service at a perinatal center]. / Taktika neonatal'noi sluzhby v perinatal'nom tsentre.

The authors analyze the development histories of 54 full-term newborns born in a satisfactory state, though in need of intensive care and rehabilitation at a special department for neonatal diseases. The absence of asphyxia at birth could not preclude a disease in the future. Analysis of mother's risk factors and neonatal disease permit a conclusion that babies born to mothers with a high-risk pregnancy even when born full-term should be singled out as a special group because of a high risk of disease development (intrauterine infection, cerebral disturbances, developmental defects, endocrine diseases, metabolic disorders, etc.). The most significant of mother's risk factors are reproductive function abnormalities (sterility, habitual abortions, a history of perinatal loss, etc.). Analysis of erroneous policy of neonatologists and late treatment start demonstrated that maternal risk factors should be more thoroughly assessed at childbirth.

[High-risk pregnancy: facts, hypotheses, conjectures]. / Beremennost' vysokogo riska: fakty, gipotezy, domysly.

Discusses the problems related to high-risk pregnancy and the effects of the so-called hazardous factors on pregnancy and the fetus. Emphasizes the necessity of revising the current notions, using present-day methods of differential diagnosis for the identification of the nature of fetal and newborn injuries.

[Compensatory potentials of the central nervous system in premature newborn infants]. / Kompensatornye vozmozhnosti tsentral'noi nervnoi sistemy u nedonoshennykh novorozhdennykh.

Compensatory potentials of the central nervous system (CNS) in preterm infants with a history of hypoxic-ischemic encephalopathy have been discussed with an emphasis on a need for revision of traditional perceptions. The use of new methods of evaluation of the developing brain indicates the phenomenon of its neurologic adaptability. It is suggested by a high incidence of CNS functional recovery in surviving preterm infants. The recovery process is phasic and bears most promise if rehabilitative interventions are individualized for every child.

[Organization of neurologic services for newborn infants in the perinatal period]. / Organizatsiia nevrologicheskoi pomoshchi novorozhdennym v perinatal'nom periode.

The authors have demonstrated the current diagnostic potentialities in the assessment of the nervous system status of the fetus and neonate, based on the use of the latest known how. New methods of all-round examinations of perinatal brain injuries given an idea of the site, character, prevalence and gravity of structural and functional brain pathology in neonates, early recognition and estimation of compensatory potencies of perinatal cerebral injuries. The reserves of preventing neurological invalidism since childhood are shown. The role of close cooperation of obstetricians, neonatologists, neuropathologists and other specialists in enhancing the efficacy of rendering neurological assistance to the newborn is emphasized as is the necessity of succession in the work of all the links in the childhood neurological services.

[A method of studying the visual evoked potentials in the evaluation of the status of the central nervous system in newborn infants]. / Metod zrite'lnykh vyzvannykh potentsialov v otsenke sostoianiia tsentra'lnoi nervnoi sistemy novorozhdennykh.

In 15 healthy mature babies and 15 newborn babies with cerebral pathology the visual evoked potentials (VEP) were investigated. The light diodes were used for stimulation. The curves preprocessed using a simple configurations technique were analysed with an euristic technique on a microcomputer. The high information value (88.5%) was attributed to VEP in cases of perinatal brain lesions. This suggested the inclusion of VEP techniques into the routine neurological investigation of the newborns.

[Morphological changes in the jejunal mucosa in vitamin D-resistant rickets]. / Morfologicheskie izmeneniia slizistoi obolochki toshchei kishki pri vitamin D-rezistentnom rakhite.

Sixteen children with vitamin-D deficiency underwent jejunoscopy with spot jejunal biopsy. Morphologic evaluation of the biopsy specimens provided evidence for glycocalyx destruction and malabsorption syndrome. Hyperactivity of hydrolytic enzymes may be concerned with the adjustment to a disturbance of the calcium/phosphorus metabolism.

[Cells from homocystinuria patients--a model for the study of the repair mechanisms in human cells]. / Kletki bol'nykh gomotsistinuriei--model' dlia izucheniia mekhanizmov reparatsii v kletkakh cheloveka.

Repair processes in blood lymphocytes of children with hereditary homocystinuria have been studied. The identical results on the defective repair processes of damaged DNA were received by the two methods used. The method of vaccinia virus reactivation registered total disturbance of the repair function in cells, while the method of alkaline elution revealed the defects in the enzymes providing resynthesis of DNA breaks in normal conditions.