Subject(s)
Back Pain/drug therapy , Drug Hypersensitivity/diagnosis , Drug-Related Side Effects and Adverse Reactions/diagnosis , Erythema Multiforme/diagnosis , Mouth Mucosa/pathology , Skin/pathology , Tramadol/therapeutic use , Administration, Oral , Allergens/immunology , Back Pain/complications , Female , Humans , Immunization , Middle Aged , Tramadol/adverse effects , Tramadol/immunologyABSTRACT
No disponible
Subject(s)
Humans , Female , Middle Aged , Erythema Multiforme/chemically induced , Analgesics, Opioid/adverse effects , Tramadol/adverse effects , Erythema Multiforme/pathology , Skin Tests , BiopsySubject(s)
Bronchial Thermoplasty/adverse effects , Bronchitis/diagnosis , Bronchitis/etiology , Adult , Asthma/complications , Asthma/diagnosis , Asthma/immunology , Asthma/therapy , Biomarkers , Bronchial Thermoplasty/methods , Bronchitis/drug therapy , Female , Humans , Hypersensitivity, Immediate/complications , Immunoglobulin E/immunology , Prednisone/administration & dosage , Prednisone/therapeutic use , Radiography, Thoracic , Severity of Illness Index , Skin TestsSubject(s)
Actins/adverse effects , Allergens/adverse effects , Fishes/immunology , Food Hypersensitivity/etiology , Poultry/immunology , Seafood/adverse effects , Actins/immunology , Adult , Allergens/immunology , Animals , Cross Reactions , Food Hypersensitivity/diagnosis , Food Hypersensitivity/immunology , Humans , Immunoglobulin E/blood , Immunoglobulin E/immunology , Male , Skin TestsSubject(s)
Allergens/adverse effects , Creatine Kinase/adverse effects , Food Hypersensitivity/etiology , Meat Proteins/adverse effects , Red Meat/adverse effects , Allergens/immunology , Animals , Creatine Kinase/immunology , Food Hypersensitivity/immunology , Humans , Immunoglobulin E/blood , Immunoglobulin E/immunology , Meat Proteins/immunology , Skin TestsABSTRACT
BACKGROUND AND OBJECTIVE: Edema of the uvula (EU) may appear in isolation or in association with clinical manifestations such as urticaria, angioedema, and anaphylaxis. EU may lead to upper airway obstruction, provoking obstructive respiratory distress and asphyxia. Objective: We sought to investigate the etiology of and predisposing factors for EU in a large population of patients referred to an outpatient clinic. METHODS: In this 3-year follow-up cohort study, 171 patients presenting with EU were identified and classified as having isolated EU or nonisolated EU. The etiology of each patient's condition was studied, and possible predisposing factors were recorded. An allergology work-up and a statistical study (bivariate/multivariate analyses) were performed. RESULTS: The predisposing factors for both groups of EU patients were found to be different. The etiology of the problem was identified for most patients; allergy to Anisakis simplex was the most common cause in both groups. Nonsteroidal anti-inflammatory drugs and antibiotics were also found to be triggers in both groups. CONCLUSIONS: Isolated EU was associated with snoring, an elongated uvula, and having experienced previous episodes of EU. We found no associations between groups of EU patients and gender, obesity, smoking, alcohol consumption, personal and family history of atopy, and obstructive sleep apnea. Allergy to A simplex was the most commonly recorded cause.
Subject(s)
Edema/epidemiology , Edema/etiology , Uvula/pathology , Adolescent , Adult , Aged , Aged, 80 and over , Disease Susceptibility , Edema/diagnosis , Female , Humans , Male , Middle Aged , Odds Ratio , Risk Assessment , Risk Factors , Skin Tests , Spain/epidemiology , Young AdultABSTRACT
No disponible
Subject(s)
Humans , Red Meat/adverse effects , Food Hypersensitivity/immunology , Hypersensitivity, Immediate/immunology , Creatine Kinase/immunology , Swine , Allergens/immunology , Case-Control StudiesABSTRACT
No disponible
Subject(s)
Humans , Male , Adult , Actins/immunology , Cross Reactions/immunology , Food Hypersensitivity/immunology , Allergens/isolation & purification , Fructose-Bisphosphate Aldolase/adverse effects , Skin Tests/methods , Phosphopyruvate Hydratase/adverse effects , Meat/adverse effects , Fish Products/adverse effectsSubject(s)
Drug Hypersensitivity/immunology , Influenza Vaccines/adverse effects , Vaccination/adverse effects , Vasculitis, Leukocytoclastic, Cutaneous/chemically induced , Aged, 80 and over , Humans , Influenza Vaccines/immunology , Influenza, Human/immunology , Male , Vasculitis, Leukocytoclastic, Cutaneous/immunologyABSTRACT
Component-resolved diagnosis based on the use of well-defined, properly characterised and purified natural and recombinant allergens constitutes a new approach in the diagnosis of venom allergy. Prospective readers may benefit from an up-to-date review on the allergens. The best characterised venom is that of Apis mellifera, whose main allergens are phospholipase A2 (Api m1), hyaluronidase (Api m2) and melittin (Api m4). Additionally, in recent years, new allergens of Vespula vulgaris have been identified and include phospholipase A1 (Ves v1), hyaluronidase (Ves v2) and antigen 5 (Ves v5). Polistes species are becoming an increasing cause of allergy in Europe, although only few allergens have been identified in this venom. In this review, we evaluate the current knowledge about molecular diagnosis in hymenoptera venom allergy
No disponible
Subject(s)
Humans , Animals , Allergens/immunology , Arthropod Venoms/immunology , Hymenoptera/immunology , Hypersensitivity/diagnosis , Insect Bites and Stings/immunology , Allergens/analysis , Allergens/chemistry , Arthropod Venoms/chemistry , Hymenoptera/chemistry , Hypersensitivity/immunology , Anaphylaxis/immunologyABSTRACT
Component-resolved diagnosis based on the use of well-defined, properly characterised and purified natural and recombinant allergens constitutes a new approach in the diagnosis of venom allergy. Prospective readers may benefit from an up-to-date review on the allergens. The best characterised venom is that of Apis mellifera, whose main allergens are phospholipase A2 (Api m1), hyaluronidase (Api m2) and melittin (Api m4). Additionally, in recent years, new allergens of Vespula vulgaris have been identified and include phospholipase A1 (Ves v1), hyaluronidase (Ves v2) and antigen 5 (Ves v5). Polistes species are becoming an increasing cause of allergy in Europe, although only few allergens have been identified in this venom. In this review, we evaluate the current knowledge about molecular diagnosis in hymenoptera venom allergy.
Subject(s)
Allergens/immunology , Arthropod Venoms/immunology , Hymenoptera/immunology , Hypersensitivity/diagnosis , Insect Bites and Stings/immunology , Allergens/analysis , Allergens/chemistry , Animals , Arthropod Venoms/chemistry , Humans , Hymenoptera/chemistry , Hypersensitivity/immunologyABSTRACT
No disponible
Subject(s)
Humans , Female , Middle Aged , Dimethyl Fumarate/adverse effects , Drug Hypersensitivity/diagnosis , Multiple Sclerosis/drug therapy , Methylprednisolone/therapeutic use , Drug Hypersensitivity/drug therapy , Skin TestsABSTRACT
No disponible
Subject(s)
Humans , Female , Adult , Antigens, Plant/isolation & purification , Lipoproteins/isolation & purification , Food Hypersensitivity/diagnosis , Hypersensitivity, Immediate/diagnosis , Helianthus/adverse effects , Seeds/adverse effects , Intradermal TestsABSTRACT
No disponible
Subject(s)
Humans , Male , Aged, 80 and over , Influenza Vaccines/adverse effects , Vasculitis, Leukocytoclastic, Cutaneous/chemically induced , Drug Hypersensitivity/diagnosis , Purpura/chemically induced , Intradermal Tests/methods , Risk FactorsSubject(s)
Anaphylaxis/immunology , Antigens, Plant/adverse effects , Carrier Proteins/adverse effects , Food Hypersensitivity/immunology , Linseed Oil/adverse effects , Plant Proteins/adverse effects , Anaphylaxis/blood , Anaphylaxis/diagnosis , Anaphylaxis/drug therapy , Anti-Allergic Agents/therapeutic use , Antigens, Plant/immunology , Biomarkers/blood , Carrier Proteins/immunology , Food Hypersensitivity/blood , Food Hypersensitivity/diagnosis , Food Hypersensitivity/drug therapy , Humans , Immunoglobulin E/blood , Immunoglobulin E/immunology , Intradermal Tests , Male , Middle Aged , Plant Proteins/immunology , Serologic Tests , Treatment OutcomeSubject(s)
Air Pollutants/adverse effects , Anaphylaxis/etiology , Anisakis/immunology , Fishes/parasitology , Adult , Animals , Female , Humans , Immunoglobulin E/blood , Skin TestsABSTRACT
No disponible
