ABSTRACT
A generalized fixed drug eruption (FDE) is an uncommon but potentially dangerous reaction to medication. In this case series, we present 1 patient with a generalized FDE and 2 patients with generalized bullous FDE that resolved with cyclosporine, though 1 patient required close monitoring in the intensive care unit. Immediate acceleration of care upon development and recognition of generalized bullous FDE is essential, as the mortality rate is similar to Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN).
Subject(s)
Drug Eruptions , Humans , Drug Eruptions/etiology , Drug Eruptions/diagnosis , Male , Female , Middle Aged , Cyclosporine/administration & dosage , Cyclosporine/adverse effects , Stevens-Johnson Syndrome/therapy , Stevens-Johnson Syndrome/diagnosis , Stevens-Johnson Syndrome/etiology , Aged , Adult , Ambulatory Care , Immunosuppressive Agents/adverse effects , Immunosuppressive Agents/administration & dosageSubject(s)
Erythema , Humans , Middle Aged , Diagnosis, Differential , Erythema/diagnosis , Erythema/pathology , Erythema/etiologyABSTRACT
Patients presenting with a linear, erythematous, blistering eruption may experience a sudden painful sunburn that seems to get worse rather than better with time. In warm climates, exposure to the common fig tree (Ficus carica) may be the culprit. Dermatologists should recognize fig phytophotodermatitis as a possible cause and help the patient connect their symptoms with the inciting agent as well as administer proper treatment.