ABSTRACT
Introduction:Migraine is a complex headache to treat, often with an unsatisfactory clinical response. Aerobic exercise, such as running, can be a non-pharmacological treatment to reduce migraine attacks. Objective:This systematic review with meta-analysis investigated the effects of running on frequency and intensity of pain in subjects with migraine compared with other or no aerobic exercise. Methods:Randomized and quasi-randomized clinical trials were searched between September and November 2021 in BVS, PubMed, Cochrane, CINAHL, SCOPUS, Embase, and Web of Science databases. The Cochrane Risk of Bias tool assessed methodological quality, and the recommendation ranking assessed the certainty of evidence. The frequency of migraine attacks was pooled in a meta-analysis (random effects) that included interval and continuous running subgroups. Results:Only two of the 483 studies analyzed were included in the review (52 individuals, 81% females). Migraine intensity was not included in the meta-analysis because only one study measured this outcome. None of the studies demonstrated that running reduced the frequency of migraine attacks (MD = -0.40 [95% CI = -1.61 to 0.81]). The studies included presented a high risk of bias and very low certainty of evidence. Conclusion:The results were not sufficient to recommend running as a treatment to reduce the frequency and intensity of migraine attacks.
Introdução: A enxaqueca é uma cefaleia complexa de tratar, muitas vezes com resposta clínica insatisfatória. O exercício aeróbico, como a corrida, pode ser um tratamento não farmacológico para reduzir as crises de enxaqueca. Objetivo: Esta revisão sistemática com meta-análise investigou os efeitos da corrida na frequência e intensidade da dor em indivíduos com enxaqueca em comparação com outros ou nenhum exercício aeróbico. Métodos:Ensaios clínicos randomizados e quase randomizados foram pesquisados ââentre setembro e novembro de 2021 nas bases de dados BVS, PubMed, Cochrane, CINAHL, SCOPUS, Embase e Web of Science. A ferramenta Cochrane Risk of Bias avaliou a qualidade metodológica e a classificação das recomendações avaliou a certeza das evidências. A frequência das crises de enxaqueca foi agrupada em uma meta-análise (efeitos aleatórios) que incluiu subgrupos de intervalo e de execução contínua. Resultados: Apenas dois dos 483 estudos analisados ââforam incluídos na revisão (52 indivíduos, 81% do sexo feminino). A intensidade da enxaqueca não foi incluída na metanálise porque apenas um estudo mediu esse resultado. Nenhum dos estudos demonstrou que correr reduziu a frequência de crises de enxaqueca (MD = -0,40 [IC 95% = -1,61 a 0,81]). Os estudos incluídos apresentaram alto risco de viés e baixíssima qualidade de evidência. Conclusão:Os resultados não foram suficientes para recomendar a corrida como tratamento para reduzir a frequência e intensidade das crises de enxaqueca.
ABSTRACT
The objective of this study was to evaluate the efficacy of proprioceptive neuromuscular facilitation (PNF) on range of motion (ROM) gain in young healthy adults. We performed a systematic review of randomized controlled trials and quasi-randomized trials, including young healthy adults. The interventions were: PNF compared with different PNF techniques, control, other muscle stretching exercises and musculoskeletal manipulations. The outcome measures were: articular ROM and adverse effects. The final number of included studies was 46, involving 1,864 adults. There was difference on ROM comparing assisted hold-relax (HR) on diagonal plane to control, based on very low-quality evidence. There was also difference on ROM comparing assisted HR to self-HR; self-contract-relax (CR) to control; assisted CR contract to control; and assisted HR contract to control, based on low-quality evidence. Moderate-quality evidence shows that results differ between self HR and control (SMD: 0.95; 95%CI 0.03, 1.86; I249%; P = 0.16) in terms of ROM gain. When performing the other comparisons, the results were based on low or very low-quality evidence and do not allow to state if PNF is more or less effective than other stretches for improving ROM in healthy young adults. No adverse effects were mentioned.