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Psiquiatr. biol. (Ed. impr.) ; 15(2): 56-58, mar. 2008.
Article in Es | IBECS | ID: ibc-65013

ABSTRACT

El síndrome de neurotoxicidad irreversible causada por litio (SILENT) agrupa un conjunto de complicaciones neurológicas que persisten más allá de 2 meses después de haber cesado el tratamiento con litio. Desconocemos la base etiopatogénica de dicho cuadro y, por tanto, el tratamiento utilizado en la actualidad es meramente sintomático. Describimos un caso a propósito de este síndrome y recordamos las medidas preventivas que aconsejan un grupo de expertos


The acronym SILENT (syndrome of irreversible lithium-effectuated neurotoxicity) has been coined to denote the neurologic sequelae of lithium intoxication persisting for at least 2 months after lithium withdrawal. The etiopathogenic mechanism of SILENT is far from clear and treatment is purely symptomatic. We describe a case of this syndrome and describe the preventive measures recommended by a group of experts


Subject(s)
Humans , Female , Middle Aged , Lithium/adverse effects , Neurotoxicity Syndromes/prevention & control , Epilepsy/chemically induced , /prevention & control , Substance-Related Disorders/drug therapy
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