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Drug-resistance mechanisms in Vibrio cholerae O1 outbreak strain, Haiti, 2010.
Sjölund-Karlsson, Maria; Reimer, Aleisha; Folster, Jason P; Walker, Matthew; Dahourou, Georges Anicet; Batra, Dhwani Govil; Martin, Irene; Joyce, Kevin; Parsons, Michele B; Boncy, Jacques; Whichard, Jean M; Gilmour, Matthew W.
Emerg Infect Dis ; 17(11): 2151-4, 2011 Nov.
Article in English | MEDLINE | ID: mdl-22099122

ABSTRACT

To increase understanding of drug-resistant Vibrio cholerae, we studied selected molecular mechanisms of antimicrobial drug resistance in the 2010 Haiti V. cholerae outbreak strain. Most resistance resulted from acquired genes located on an integrating conjugative element showing high homology to an integrating conjugative element identified in a V. cholerae isolate from India.


Subject(s)
Cholera/epidemiology , Disease Outbreaks , Drug Resistance, Multiple, Bacterial , Vibrio cholerae O1/drug effects , Anti-Bacterial Agents/pharmacology , Drug Resistance, Multiple, Bacterial/genetics , Gene Order , Genome, Bacterial , Haiti/epidemiology , Humans , Microbial Sensitivity Tests , Phylogeny , Vibrio cholerae O1/genetics , Vibrio cholerae O1/isolation & purification
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