Automated characterization and detection of fibromyalgia using slow wave sleep EEG signals with glucose pattern and D'hondt pooling technique.

Fibromyalgia is a soft tissue rheumatism with significant qualitative and quantitative impact on sleep macro and micro architecture. The primary objective of this study is to analyze and identify automatically healthy individuals and those with fibromyalgia using sleep electroencephalography (EEG) signals. The study focused on the automatic detection and interpretation of EEG signals obtained from fibromyalgia patients. In this work, the sleep EEG signals are divided into 15-s and a total of 5358 (3411 healthy control and 1947 fibromyalgia) EEG segments are obtained from 16 fibromyalgia and 16 normal subjects. Our developed model has advanced multilevel feature extraction architecture and hence, we used a new feature extractor called GluPat, inspired by the glucose chemical, with a new pooling approach inspired by the D'hondt selection system. Furthermore, our proposed method incorporated feature selection techniques using iterative neighborhood component analysis and iterative Chi2 methods. These selection mechanisms enabled the identification of discriminative features for accurate classification. In the classification phase, we employed a support vector machine and k-nearest neighbor algorithms to classify the EEG signals with leave-one-record-out (LORO) and tenfold cross-validation (CV) techniques. All results are calculated channel-wise and iterative majority voting is used to obtain generalized results. The best results were determined using the greedy algorithm. The developed model achieved a detection accuracy of 100% and 91.83% with a tenfold and LORO CV strategies, respectively using sleep stage (2 + 3) EEG signals. Our generated model is simple and has linear time complexity.

FLP: Factor lattice pattern-based automated detection of Parkinson's disease and specific language impairment using recorded speech.

BACKGROUND: Timely detection of neurodevelopmental and neurological conditions is crucial for early intervention. Specific Language Impairment (SLI) in children and Parkinson's disease (PD) manifests in speech disturbances that may be exploited for diagnostic screening using recorded speech signals. We were motivated to develop an accurate yet computationally lightweight model for speech-based detection of SLI and PD, employing novel feature engineering techniques to mimic the adaptable dynamic weight assignment network capability of deep learning architectures. MATERIALS AND METHODS: In this research, we have introduced an advanced feature engineering model incorporating a novel feature extraction function, the Factor Lattice Pattern (FLP), which is a quantum-inspired method and uses a superposition-like mechanism, making it dynamic in nature. The FLP encompasses eight distinct patterns, from which the most appropriate pattern was discerned based on the data structure. Through the implementation of the FLP, we automatically extracted signal-specific textural features. Additionally, we developed a new feature engineering model to assess the efficacy of the FLP. This model is self-organizing, producing nine potential results and subsequently choosing the optimal one. Our speech classification framework consists of (1) feature extraction using the proposed FLP and a statistical feature extractor; (2) feature selection employing iterative neighborhood component analysis and an intersection-based feature selector; (3) classification via support vector machine and k-nearest neighbors; and (4) outcome determination using combinational majority voting to select the most favorable results. RESULTS: To validate the classification capabilities of our proposed feature engineering model, designed to automatically detect PD and SLI, we employed three speech datasets of PD and SLI patients. Our presented FLP-centric model achieved classification accuracy of more than 95% and 99.79% for all PD and SLI datasets, respectively. CONCLUSIONS: Our results indicate that the proposed model is an accurate alternative to deep learning models in classifying neurological conditions using speech signals.

Automated anxiety detection using probabilistic binary pattern with ECG signals.

BACKGROUND AND AIM: Anxiety disorder is common; early diagnosis is crucial for management. Anxiety can induce physiological changes in the brain and heart. We aimed to develop an efficient and accurate handcrafted feature engineering model for automated anxiety detection using ECG signals. MATERIALS AND METHODS: We studied open-access electrocardiography (ECG) data of 19 subjects collected via wearable sensors while they were shown videos that might induce anxiety. Using the Hamilton Anxiety Rating Scale, subjects are categorized into normal, light anxiety, moderate anxiety, and severe anxiety groups. ECGs were divided into non-overlapping 4- (Case 1), 5- (Case 2), and 6-second (Case 3) segments for analysis. We proposed a self-organized dynamic pattern-based feature extraction function-probabilistic binary pattern (PBP)-in which patterns within the function were determined by the probabilities of the input signal-dependent values. This was combined with tunable q-factor wavelet transform to facilitate multileveled generation of feature vectors in both spatial and frequency domains. Neighborhood component analysis and Chi2 functions were used to select features and reduce data dimensionality. Shallow k-nearest neighbors and support vector machine classifiers were used to calculate four (=2 × 2) classifier-wise results per input signal. From the latter, novel self-organized combinational majority voting was applied to calculate an additional five voted results. The optimal final model outcome was chosen from among the nine (classifier-wise and voted) results using a greedy algorithm. RESULTS: Our model achieved classification accuracies of over 98.5 % for all three cases. Ablation studies confirmed the incremental accuracy of PBP-based feature engineering over traditional local binary pattern feature extraction. CONCLUSIONS: The results demonstrated the feasibility and accuracy of our PBP-based feature engineering model for anxiety classification using ECG signals.

PFP-HOG: Pyramid and Fixed-Size Patch-Based HOG Technique for Automated Brain Abnormality Classification with MRI.

Detecting neurological abnormalities such as brain tumors and Alzheimer's disease (AD) using magnetic resonance imaging (MRI) images is an important research topic in the literature. Numerous machine learning models have been used to detect brain abnormalities accurately. This study addresses the problem of detecting neurological abnormalities in MRI. The motivation behind this problem lies in the need for accurate and efficient methods to assist neurologists in the diagnosis of these disorders. In addition, many deep learning techniques have been applied to MRI to develop accurate brain abnormality detection models, but these networks have high time complexity. Hence, a novel hand-modeled feature-based learning network is presented to reduce the time complexity and obtain high classification performance. The model proposed in this work uses a new feature generation architecture named pyramid and fixed-size patch (PFP). The main aim of the proposed PFP structure is to attain high classification performance using essential feature extractors with both multilevel and local features. Furthermore, the PFP feature extractor generates low- and high-level features using a handcrafted extractor. To obtain the high discriminative feature extraction ability of the PFP, we have used histogram-oriented gradients (HOG); hence, it is named PFP-HOG. Furthermore, the iterative Chi2 (IChi2) is utilized to choose the clinically significant features. Finally, the k-nearest neighbors (kNN) with tenfold cross-validation is used for automated classification. Four MRI neurological databases (AD dataset, brain tumor dataset 1, brain tumor dataset 2, and merged dataset) have been utilized to develop our model. PFP-HOG and IChi2-based models attained 100%, 94.98%, 98.19%, and 97.80% using the AD dataset, brain tumor dataset1, brain tumor dataset 2, and merged brain MRI dataset, respectively. These findings not only provide an accurate and robust classification of various neurological disorders using MRI but also hold the potential to assist neurologists in validating manual MRI brain abnormality screening.

Primate brain pattern-based automated Alzheimer's disease detection model using EEG signals.

Electroencephalography (EEG) may detect early changes in Alzheimer's disease (AD), a debilitating progressive neurodegenerative disease. We have developed an automated AD detection model using a novel directed graph for local texture feature extraction with EEG signals. The proposed graph was created from a topological map of the macroscopic connectome, i.e., neuronal pathways linking anatomo-functional brain segments involved in visual object recognition and motor response in the primate brain. This primate brain pattern (PBP)-based model was tested on a public AD EEG signal dataset. The dataset comprised 16-channel EEG signal recordings of 12 AD patients and 11 healthy controls. While PBP could generate 448 low-level features per one-dimensional EEG signal, combining it with tunable q-factor wavelet transform created a multilevel feature extractor (which mimicked deep models) to generate 8,512 (= 448 × 19) features per signal input. Iterative neighborhood component analysis was used to choose the most discriminative features (the number of optimal features varied among the individual EEG channels) to feed to a weighted k-nearest neighbor (KNN) classifier for binary classification into AD vs. healthy using both leave-one subject-out (LOSO) and tenfold cross-validations. Iterative majority voting was used to compute subject-level general performance results from the individual channel classification outputs. Channel-wise, as well as subject-level general results demonstrated exemplary performance. In addition, the model attained 100% and 92.01% accuracy for AD vs. healthy classification using the KNN classifier with tenfold and LOSO cross-validations, respectively. Our developed multilevel PBP-based model extracted discriminative features from EEG signals and paved the way for further development of models inspired by the brain connectome.

ExHiF: Alzheimer's disease detection using exemplar histogram-based features with CT and MR images.

PURPOSE: The classification of medical images is an important priority for clinical research and helps to improve the diagnosis of various disorders. This work aims to classify the neuroradiological features of patients with Alzheimer's disease (AD) using an automatic hand-modeled method with high accuracy. MATERIALS AND METHOD: This work uses two (private and public) datasets. The private dataset consists of 3807 magnetic resonance imaging (MRI) and computer tomography (CT) images belonging to two (normal and AD) classes. The second public (Kaggle AD) dataset contains 6400 MR images. The presented classification model comprises three fundamental phases: feature extraction using an exemplar hybrid feature extractor, neighborhood component analysis-based feature selection, and classification utilizing eight different classifiers. The novelty of this model is feature extraction. Vision transformers inspire this phase, and hence 16 exemplars are generated. Histogram-oriented gradients (HOG), local binary pattern (LBP) and local phase quantization (LPQ) feature extraction functions have been applied to each exemplar/patch and raw brain image. Finally, the created features are merged, and the best features are selected using neighborhood component analysis (NCA). These features are fed to eight classifiers to obtain highest classification performance using our proposed method. The presented image classification model uses exemplar histogram-based features; hence, it is called ExHiF. RESULTS: We have developed the ExHiF model with a ten-fold cross-validation strategy using two (private and public) datasets with shallow classifiers. We have obtained 100% classification accuracy using cubic support vector machine (CSVM) and fine k nearest neighbor (FkNN) classifiers for both datasets. CONCLUSIONS: Our developed model is ready to be validated with more datasets and has the potential to be employed in mental hospitals to assist neurologists in confirming their manual screening of AD using MRI/CT images.

PatchResNet: Multiple Patch Division-Based Deep Feature Fusion Framework for Brain Tumor Classification Using MRI Images.

Modern computer vision algorithms are based on convolutional neural networks (CNNs), and both end-to-end learning and transfer learning modes have been used with CNN for image classification. Thus, automated brain tumor classification models have been proposed by deploying CNNs to help medical professionals. Our primary objective is to increase the classification performance using CNN. Therefore, a patch-based deep feature engineering model has been proposed in this work. Nowadays, patch division techniques have been used to attain high classification performance, and variable-sized patches have achieved good results. In this work, we have used three types of patches of different sizes (32 × 32, 56 × 56, 112 × 112). Six feature vectors have been obtained using these patches and two layers of the pretrained ResNet50 (global average pooling and fully connected layers). In the feature selection phase, three selectors-neighborhood component analysis (NCA), Chi2, and ReliefF-have been used, and 18 final feature vectors have been obtained. By deploying k nearest neighbors (kNN), 18 results have been calculated. Iterative hard majority voting (IHMV) has been applied to compute the general classification accuracy of this framework. This model uses different patches, feature extractors (two layers of the ResNet50 have been utilized as feature extractors), and selectors, making this a framework that we have named PatchResNet. A public brain image dataset containing four classes (glioblastoma multiforme (GBM), meningioma, pituitary tumor, healthy) has been used to develop the proposed PatchResNet model. Our proposed PatchResNet attained 98.10% classification accuracy using the public brain tumor image dataset. The developed PatchResNet model obtained high classification accuracy and has the advantage of being a self-organized framework. Therefore, the proposed method can choose the best result validation prediction vectors and achieve high image classification performance.

Swin-textural: A novel textural features-based image classification model for COVID-19 detection on chest computed tomography.

Background: Chest computed tomography (CT) has a high sensitivity for detecting COVID-19 lung involvement and is widely used for diagnosis and disease monitoring. We proposed a new image classification model, swin-textural, that combined swin-based patch division with textual feature extraction for automated diagnosis of COVID-19 on chest CT images. The main objective of this work is to evaluate the performance of the swin architecture in feature engineering. Material and method: We used a public dataset comprising 2167, 1247, and 757 (total 4171) transverse chest CT images belonging to 80, 80, and 50 (total 210) subjects with COVID-19, other non-COVID lung conditions, and normal lung findings. In our model, resized 420 × 420 input images were divided using uniform square patches of incremental dimensions, which yielded ten feature extraction layers. At each layer, local binary pattern and local phase quantization operations extracted textural features from individual patches as well as the undivided input image. Iterative neighborhood component analysis was used to select the most informative set of features to form ten selected feature vectors and also used to select the 11th vector from among the top selected feature vectors with accuracy >97.5%. The downstream kNN classifier calculated 11 prediction vectors. From these, iterative hard majority voting generated another nine voted prediction vectors. Finally, the best result among the twenty was determined using a greedy algorithm. Results: Swin-textural attained 98.71% three-class classification accuracy, outperforming published deep learning models trained on the same dataset. The model has linear time complexity. Conclusions: Our handcrafted computationally lightweight swin-textural model can detect COVID-19 accurately on chest CT images with low misclassification rates. The model can be implemented in hospitals for efficient automated screening of COVID-19 on chest CT images. Moreover, findings demonstrate that our presented swin-textural is a self-organized, highly accurate, and lightweight image classification model and is better than the compared deep learning models for this dataset.

Automated Adrenal Gland Disease Classes Using Patch-Based Center Symmetric Local Binary Pattern Technique with CT Images.

Incidental adrenal masses are seen in 5% of abdominal computed tomography (CT) examinations. Accurate discrimination of the possible differential diagnoses has important therapeutic and prognostic significance. A new handcrafted machine learning method has been developed for the automated and accurate classification of adrenal gland CT images. A new dataset comprising 759 adrenal gland CT image slices from 96 subjects were analyzed. Experts had labeled the collected images into four classes: normal, pheochromocytoma, lipid-poor adenoma, and metastasis. The images were preprocessed, resized, and the image features were extracted using the center symmetric local binary pattern (CS-LBP) method. CT images were next divided into 16 × 16 fixed-size patches, and further feature extraction using CS-LBP was performed on these patches. Next, extracted features were selected using neighborhood component analysis (NCA) to obtain the most meaningful ones for downstream classification. Finally, the selected features were classified using k-nearest neighbor (kNN), support vector machine (SVM), and neural network (NN) classifiers to obtain the optimum performing model. Our proposed method obtained an accuracy of 99.87%, 99.21%, and 98.81% with kNN, SVM, and NN classifiers, respectively. Hence, the kNN classifier yielded the highest classification results with no pathological image misclassified as normal. Our developed fixed patch CS-LBP-based automatic classification of adrenal gland pathologies on CT images is highly accurate and has low time complexity [Formula: see text]. It has the potential to be used for screening of adrenal gland disease classes with CT images.

CCPNet136: automated detection of schizophrenia using carbon chain pattern and iterative TQWT technique with EEG signals.

Objective.Schizophrenia (SZ) is a severe, chronic psychiatric-cognitive disorder. The primary objective of this work is to present a handcrafted model using state-of-the-art technique to detect SZ accurately with EEG signals.Approach.In our proposed work, the features are generated using a histogram-based generator and an iterative decomposition model. The graph-based molecular structure of the carbon chain is employed to generate low-level features. Hence, the developed feature generation model is called the carbon chain pattern (CCP). An iterative tunable q-factor wavelet transform (ITQWT) technique is implemented in the feature extraction phase to generate various sub-bands of the EEG signal. The CCP was applied to the generated sub-bands to obtain several feature vectors. The clinically significant features were selected using iterative neighborhood component analysis (INCA). The selected features were then classified using the k nearest neighbor (kNN) with a 10-fold cross-validation strategy. Finally, the iterative weighted majority method was used to obtain the results in multiple channels.Main results.The presented CCP-ITQWT and INCA-based automated model achieved an accuracy of 95.84% and 99.20% using a single channel and majority voting method, respectively with kNN classifier.Significance.Our results highlight the success of the proposed CCP-ITQWT and INCA-based model in the automated detection of SZ using EEG signals.

Multilevel hybrid accurate handcrafted model for myocardial infarction classification using ECG signals.

Myocardial infarction (MI) is detected using electrocardiography (ECG) signals. Machine learning (ML) models have been used for automated MI detection on ECG signals. Deep learning models generally yield high classification performance but are computationally intensive. We have developed a novel multilevel hybrid feature extraction-based classification model with low time complexity for MI classification. The study dataset comprising 12-lead ECGs belonging to one healthy and 10 MI classes were downloaded from a public ECG signal databank. The model architecture comprised multilevel hybrid feature extraction, iterative feature selection, classification, and iterative majority voting (IMV). In the hybrid handcrafted feature (HHF) generation phase, both textural and statistical feature extraction functions were used to extract features from ECG beats but only at a low level. A new pooling-based multilevel decomposition model was presented to enable them to create features at a high level. This model used average and maximum pooling to create decomposed signals. Using these pooling functions, an unbalanced tree was obtained. Therefore, this model was named multilevel unbalanced pooling tree transformation (MUPTT). On the feature extraction side, two extractors (functions) were used to generate both statistical and textural features. To generate statistical features, 20 commonly used moments were used. A new, improved symmetric binary pattern function was proposed to generate textural features. Both feature extractors were applied to the original MI signal and the decomposed signals generated by the MUPTT. The most valuable features from among the extracted feature vectors were selected using iterative neighborhood component analysis (INCA). In the classification phase, a one-dimensional nearest neighbor classifier with ten-fold cross-validation was used to obtain lead-wise results. The computed lead-wise results derived from all 12 leads of the same beat were input to the IMV algorithm to generate ten voted results. The most representative was chosen using a greedy technique to calculate the overall classification performance of the model. The HHF-MUPTT-based ECG beat classification model attained excellent performance, with the best lead-wise accuracy of 99.85% observed in Lead III and 99.94% classification accuracy using the IMV algorithm. The results confirmed the high MI classification ability of the presented computationally lightweight HHF-MUPTT-based model.

Hamlet-Pattern-Based Automated COVID-19 and Influenza Detection Model Using Protein Sequences.

SARS-CoV-2 and Influenza-A can present similar symptoms. Computer-aided diagnosis can help facilitate screening for the two conditions, and may be especially relevant and useful in the current COVID-19 pandemic because seasonal Influenza-A infection can still occur. We have developed a novel text-based classification model for discriminating between the two conditions using protein sequences of varying lengths. We downloaded viral protein sequences of SARS-CoV-2 and Influenza-A with varying lengths (all 100 or greater) from the NCBI database and randomly selected 16,901 SARS-CoV-2 and 19,523 Influenza-A sequences to form a two-class study dataset. We used a new feature extraction function based on a unique pattern, HamletPat, generated from the text of Shakespeare's Hamlet, and a signum function to extract local binary pattern-like bits from overlapping fixed-length (27) blocks of the protein sequences. The bits were converted to decimal map signals from which histograms were extracted and concatenated to form a final feature vector of length 1280. The iterative Chi-square function selected the 340 most discriminative features to feed to an SVM with a Gaussian kernel for classification. The model attained 99.92% and 99.87% classification accuracy rates using hold-out (75:25 split ratio) and five-fold cross-validations, respectively. The excellent performance of the lightweight, handcrafted HamletPat-based classification model suggests that it can be a valuable tool for screening protein sequences to discriminate between SARS-CoV-2 and Influenza-A infections.

Automated detection of pain levels using deep feature extraction from shutter blinds-based dynamic-sized horizontal patches with facial images.

Pain intensity classification using facial images is a challenging problem in computer vision research. This work proposed a patch and transfer learning-based model to classify various pain intensities using facial images. The input facial images were segmented into dynamic-sized horizontal patches or "shutter blinds". A lightweight deep network DarkNet19 pre-trained on ImageNet1K was used to generate deep features from the shutter blinds and the undivided resized segmented input facial image. The most discriminative features were selected from these deep features using iterative neighborhood component analysis, which were then fed to a standard shallow fine k-nearest neighbor classifier for classification using tenfold cross-validation. The proposed shutter blinds-based model was trained and tested on datasets derived from two public databases-University of Northern British Columbia-McMaster Shoulder Pain Expression Archive Database and Denver Intensity of Spontaneous Facial Action Database-which both comprised four pain intensity classes that had been labeled by human experts using validated facial action coding system methodology. Our shutter blinds-based classification model attained more than 95% overall accuracy rates on both datasets. The excellent performance suggests that the automated pain intensity classification model can be deployed to assist doctors in the non-verbal detection of pain using facial images in various situations (e.g., non-communicative patients or during surgery). This system can facilitate timely detection and management of pain.

TMP19: A Novel Ternary Motif Pattern-Based ADHD Detection Model Using EEG Signals.

Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental condition worldwide. In this research, we used an ADHD electroencephalography (EEG) dataset containing more than 4000 EEG signals. Moreover, these EEGs are noisy signals. A new hand-modeled EEG classification model has been proposed to separate healthy versus ADHD individuals using the EEG signals. In this model, a new ternary motif pattern (TMP) has been incorporated. We have mimicked deep learning networks to create this hand-modeled classification method. The Tunable Q Wavelet Transform (TQWT) has been utilized to generate wavelet subbands. We applied the proposed TMP and statistics to construct informative features from both raw EEG signals and wavelet bands by generating TQWT. Herein, features have been generated by 18 subbands and the original EEG signal. Thus, this model is named TMP19. The most informative features have been chosen by deploying neighborhood component analysis (NCA), and the selected features have been classified using the k-nearest neighbor (kNN) classifier. The used ADHD EEG dataset has 14 channels. Thus, these three phases-(i) feature extraction with TQWT, TMP, and statistics; (ii) feature selection by deploying NCA; and (iii) classification with kNN-have been applied to each channel. Iterative hard majority voting (IHMV) has been applied to obtain a higher and more general classification response. Our model attained 95.57% and 77.93% classification accuracies by deploying 10-fold and leave one subject out (LOSO) cross-validations, respectively.

Automated Diabetic Retinopathy Detection Using Horizontal and Vertical Patch Division-Based Pre-Trained DenseNET with Digital Fundus Images.

Diabetic retinopathy (DR) is a common complication of diabetes that can lead to progressive vision loss. Regular surveillance with fundal photography, early diagnosis, and prompt intervention are paramount to reducing the incidence of DR-induced vision loss. However, manual interpretation of fundal photographs is subject to human error. In this study, a new method based on horizontal and vertical patch division was proposed for the automated classification of DR images on fundal photographs. The novel sides of this study are given as follows. We proposed a new non-fixed-size patch division model to obtain high classification results and collected a new fundus image dataset. Moreover, two datasets are used to test the model: a newly collected three-class (normal, non-proliferative DR, and proliferative DR) dataset comprising 2355 DR images and the established open-access five-class Asia Pacific Tele-Ophthalmology Society (APTOS) 2019 dataset comprising 3662 images. Two analysis scenarios, Case 1 and Case 2, with three (normal, non-proliferative DR, and proliferative DR) and five classes (normal, mild DR, moderate DR, severe DR, and proliferative DR), respectively, were derived from the APTOS 2019 dataset. These datasets and these cases have been used to demonstrate the general classification performance of our proposal. By applying transfer learning, the last fully connected and global average pooling layers of the DenseNet201 architecture were used to extract deep features from input DR images and each of the eight subdivided horizontal and vertical patches. The most discriminative features are then selected using neighborhood component analysis. These were fed as input to a standard shallow cubic support vector machine for classification. Our new DR dataset obtained 94.06% and 91.55% accuracy values for three-class classification with 80:20 hold-out validation and 10-fold cross-validation, respectively. As can be seen from steps of the proposed model, a new patch-based deep-feature engineering model has been proposed. The proposed deep-feature engineering model is a cognitive model, since it uses efficient methods in each phase. Similar excellent results were seen for three-class classification with the Case 1 dataset. In addition, the model attained 87.43% and 84.90% five-class classification accuracy rates using 80:20 hold-out validation and 10-fold cross-validation, respectively, on the Case 2 dataset, which outperformed prior DR classification studies based on the five-class APTOS 2019 dataset. Our model attained about >2% classification results compared to others. These findings demonstrate the accuracy and robustness of the proposed model for classification of DR images.

Novel nested patch-based feature extraction model for automated Parkinson's Disease symptom classification using MRI images.

OBJECTIVE: Parkinson's disease (PD) is a common neurological disorder with variable clinical manifestations and magnetic resonance imaging (MRI) findings. We propose a handcrafted image classification model that can accurately (i) classify different PD stages, (ii) detect comorbid dementia, and (iii) discriminate PD-related motor symptoms. METHODS: Selected image datasets from three PD studies were used to develop the classification model. Our proposed novel automated system was developed in four phases: (i) texture features are extracted from the non-fixed size patches. In the feature extraction phase, a pyramid histogram-oriented gradient (PHOG) image descriptor is used. (ii) In the feature selection phase, four feature selectors: neighborhood component analysis (NCA), Chi2, minimum redundancy maximum relevancy (mRMR), and ReliefF are used to generate four feature vectors. (iii) Two classifiers: k-nearest neighbor (kNN) and support vector machine (SVM) are used in the classification step. A ten-fold cross-validation technique is used to validate the results. (iv) Eight predicted vectors are generated using four selected feature vectors and two classifiers. Finally, iterative majority voting (IMV) is used to attain general classification results. Therefore, this model is named nested patch-PHOG-multiple feature selectors and multiple classifiers-IMV (NP-PHOG-MFSMCIMV). RESULTS: Our presented NP-PHOG-MFSMCIMV model achieved 99.22, 98.70, and 99.53% accuracies for the collected PD stages, PD dementia, and PD symptoms classification datasets, respectively. SIGNIFICANCE: The obtained accuracies (over 98% for all states) demonstrated the performance of developed NP-PHOG-MFSMCIMV model in automated PD state classification.

An accurate valvular heart disorders detection model based on a new dual symmetric tree pattern using stethoscope sounds.

BACKGROUND AND PURPOSE: Valvular heart disease (VHD) is an important cause of morbidity and mortality. Echocardiography is the reference standard for VHD diagnosis but is not universally accessible. Manual cardiac auscultation is inadequate for screening VHD. Many machine learning models using heart sounds acquired with an electronic stethoscope may improve the accuracy of VHD diagnosis. We aimed to develop an accurate sound classification model for VHD diagnosis. MATERIALS AND METHODS: A new large stethoscope sound dataset containing 10,366 heart sounds divided into ten categories (nine VHD and one healthy) were prospectively collected. We developed a handcrafted learning model that comprised multilevel feature extraction based on a dual symmetric tree pattern (DSTP) and multilevel discrete wavelet transform (DWT), feature selection, and classification. The multilevel DWT was used to create subbands to extract features at both high and low levels. Then, iterative neighborhood component analysis was used to select the most discriminative 512 features from among the extracted features in the generated feature vector. In the classification phase, a support vector machine (SVM) was used with 10-fold cross-validation (CV) and leave-one-subject-out (LOSO) CV. RESULTS: Our proposed DSTP-based model attained 99.58% and 99.84% classification accuracies using SVM classifier with 10-fold CV and LOSO CV, respectively. CONCLUSIONS: The presented DSTP-based classification model attained excellent multiclass classification performance on a large prospective heart sound dataset at a low computational cost.

CGP17Pat: Automated Schizophrenia Detection Based on a Cyclic Group of Prime Order Patterns Using EEG Signals.

BACKGROUND AND PURPOSE: Machine learning models have been used to diagnose schizophrenia. The main purpose of this research is to introduce an effective schizophrenia hand-modeled classification method. METHOD: A public electroencephalogram (EEG) signal data set was used in this work, and an automated schizophrenia detection model is presented using a cyclic group of prime order with a modulo 17 operator. Therefore, the presented feature extractor was named as the cyclic group of prime order pattern, CGP17Pat. Using the proposed CGP17Pat, a new multilevel feature extraction model is presented. To choose a highly distinctive feature, iterative neighborhood component analysis (INCA) was used, and these features were classified using k-nearest neighbors (kNN) with the 10-fold cross-validation and leave-one-subject-out (LOSO) validation techniques. Finally, iterative hard majority voting was employed in the last phase to obtain channel-wise results, and the general results were calculated. RESULTS: The presented CGP17Pat-based EEG classification model attained 99.91% accuracy employing 10-fold cross-validation and 84.33% accuracy using the LOSO strategy. CONCLUSIONS: The findings and results depicted the high classification ability of the presented cryptologic pattern for the data set used.

Exemplar Darknet19 feature generation technique for automated kidney stone detection with coronal CT images.

Kidney stone is a commonly seen ailment and is usually detected by urologists using computed tomography (CT) images. It is difficult and time-consuming to detect small stones in CT images. Hence, an automated system can help clinicians to detect kidney stones accurately. In this work, a novel transfer learning-based image classification method (ExDark19) has been proposed to detect kidney stones using CT images. The iterative neighborhood component analysis (INCA) is employed to select the most informative feature vectors and these selected features vectors are fed to the k nearest neighbor (kNN) classifier to detect kidney stones with a ten-fold cross-validation (CV) strategy. The proposed ExDark19 model yielded an accuracy of 99.22% with 10-fold CV and 99.71% using the hold-out validation method. Our results demonstrate that the proposed ExDark19 detect kidney stones over 99% accuracies for two validation techniques. This developed automated system can assist the urologists to validate their manual screening of kidney stones and hence reduce the possible human error.

A Hand-Modeled Feature Extraction-Based Learning Network to Detect Grasps Using sEMG Signal.

Recently, deep models have been very popular because they achieve excellent performance with many classification problems. Deep networks have high computational complexities and require specific hardware. To overcome this problem (without decreasing classification ability), a hand-modeled feature selection method is proposed in this paper. A new shape-based local feature extractor is presented which uses the geometric shape of the frustum. By using a frustum pattern, textural features are generated. Moreover, statistical features have been extracted in this model. Textures and statistics features are fused, and a hybrid feature extraction phase is obtained; these features are low-level. To generate high level features, tunable Q factor wavelet transform (TQWT) is used. The presented hybrid feature generator creates 154 feature vectors; hence, it is named Frustum154. In the multilevel feature creation phase, this model can select the appropriate feature vectors automatically and create the final feature vector by merging the appropriate feature vectors. Iterative neighborhood component analysis (INCA) chooses the best feature vector, and shallow classifiers are then used. Frustum154 has been tested on three basic hand-movement sEMG datasets. Hand-movement sEMG datasets are commonly used in biomedical engineering, but there are some problems in this area. The presented models generally required one dataset to achieve high classification ability. In this work, three sEMG datasets have been used to test the performance of Frustum154. The presented model is self-organized and selects the most informative subbands and features automatically. It achieved 98.89%, 94.94%, and 95.30% classification accuracies using shallow classifiers, indicating that Frustum154 can improve classification accuracy.