1.
J Pediatr
; 155(5): 743-5, 2009 Nov.
Article
in English
| MEDLINE
| ID: mdl-19840616
ABSTRACT
Intraventricular hemorrhage is a common complication of preterm infants. Mutations in the type IV procollagen gene, COL4A1, are associated with cerebral small vessel disease with hemorrhage in adults and fetuses. We report a rare variant in COL4A1 associated with intraventricular hemorrhage in dizygotic preterm twins. These results expand the spectrum of diseases attributable to mutations in type IV procollagens.