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5.
Clín. investig. ginecol. obstet. (Ed. impr.) ; 37(4): 169-172, ago. 2010. ilus, tab
Article in Spanish | IBECS | ID: ibc-87505

ABSTRACT

El carcinosarcoma de ovario es una forma infrecuente de neoplasia maligna del ovario con presencia de elementos carcinomatosos y sarcomatosos. Es un tipo histológico agresivo que a menudo se presenta en estadios ya avanzados y con mal pronóstico. La cirugía citorreductora óptima y la quimioterapia combinada con base de platino parecen tener los mejores resultados. En el siguiente artículo presentamos el caso de una mujer asintomática de 58 años con diagnóstico de carcinosarcoma de ovario estadio IIIC de la FIGO tratada con cirugía citorreductora óptima y quimioterapia con cisplatino/ifosfamida con respuesta completa y excelente evolución a los 6 meses de la intervención (AU)


Ovarian carcinosarcoma is a very rare form of ovarian cancer, with both carcinomatous and sarcomatous components. This aggressive histological type often presents in advanced FIGO stages and has poor prognosis. Optimal cytoreductive surgery plus platinum-based combination chemotherapy are associated with better outcomes. We present the case of an asymptomatic 58-year-old woman diagnosed with stage IV ovarian carcinosarcoma treated with optimal cytoreductive surgery and chemotherapy with cisplatin/ifosfamide. The patient showed complete response with excellent outcome at 6 months of the intervention (AU)


Subject(s)
Humans , Female , Middle Aged , Ovarian Neoplasms/therapy , Ovarian Neoplasms/diagnosis , Carcinosarcoma/therapy , Carcinosarcoma/diagnosis , Treatment Outcome
6.
Gynecol Obstet Invest ; 68(1): 65-70, 2009.
Article in English | MEDLINE | ID: mdl-19407458

ABSTRACT

OBJECTIVE: The aim of this study was to determine the incidence of overactive bladder (OAB) after vaginal hysterectomy for pelvic organ prolapse (POP) and analyze the associated risk factors. STUDY DESIGN: This was a retrospective cohort study of 217 patients who underwent primary POP vaginal surgery between the years 2000 and 2004 in Donostia Hospital and who did not report OAB before surgery. A personal interview was undertaken after surgery for the diagnosis of OAB, taking into account the ICS 2002 definition. Descriptive statistical analyses and multivariate logistic regression were performed to determine the factors associated with the development of OAB after POP surgery. RESULTS: De novo OAB was diagnosed in 43 (19.8%) patients. The median time at onset of OAB symptoms after surgery was 3 months. Urge urinary incontinence was present in 28 patients (12.9%). Those women operated on also for stress urinary incontinence were at an increased risk for de novo OAB. CONCLUSION: Nearly 20% of women operated on for POP develop OAB soon after surgery. Those operated on for POP and stress urinary incontinence are more at risk.


Subject(s)
Hysterectomy, Vaginal/adverse effects , Urinary Bladder, Overactive/epidemiology , Uterine Prolapse/surgery , Aged , Cohort Studies , Female , Humans , Incidence , Logistic Models , Middle Aged , Postoperative Complications , Retrospective Studies , Surveys and Questionnaires , Treatment Outcome , Urinary Bladder, Overactive/complications , Uterine Prolapse/complications , Uterine Prolapse/epidemiology
7.
Article in Es | IBECS | ID: ibc-63007

ABSTRACT

La muerte fetal supone más de la mitad de las muertes perinatales. El grupo con mayor morbimortalidad corresponde a los recién nacidos que asocian prematuridad y bajo peso. Hay una marcada tendencia a repetir el mal resultado de la gestación anterior. Se presentan 2 casos de muerte fetal, y se realiza una revisión de las causas más frecuentes y de su influencia. El estudio de las alteraciones maternas, fetales y placentarias puede, en algunos casos, establecer la etiología de la muerte fetal (AU)


Fetal death represents more than half of perinatal deaths. Morbidity is highest in newborns who associate prematurity and low birth weight. Adverse pregnancy outcomes show a marked tendency to be repeated. We present two cases of fetal death and review the most frequent causes of this adverse outcome and their influence. Study of maternal, fetal and placental alterations can sometimes establish the etiology of fetal death (AU)


Subject(s)
Humans , Female , Adult , Risk Factors , Fetal Death/complications , Fetal Death/diagnosis , Fetal Death/etiology , Placental Insufficiency/complications , Placental Insufficiency/diagnosis , Placental Insufficiency/mortality , Dilatation and Curettage/methods , Placental Insufficiency/etiology , Placental Insufficiency/physiopathology , Acetaminophen/therapeutic use , Misoprostol/therapeutic use , Listeria/isolation & purification , Listeria/pathogenicity
8.
Int Urogynecol J Pelvic Floor Dysfunct ; 18(11): 1317-24, 2007 Nov.
Article in English | MEDLINE | ID: mdl-17333439

ABSTRACT

The objective of this study was to determine the factors associated with the anatomic and functional recurrence of prolapse. An examination was performed in 134 of the 228 patients who underwent primary vaginal surgery for prolapse of the pelvic organs (POP) between 2000 and 2001. Anatomical recurrence of the prolapse was established by pelvic examination using the pelvic organ prolapse quantification (POPQ) staging system. Functional results were obtained by interview with the patients. Descriptive statistical analyses and multivariate logistic regression were performed to determine the factors associated with recurrence. Five years after surgery, 42 women (31.3%) presented anatomical recurrence of the prolapse (grade > or = II), and only 10 of the 134 (7.4%) had prolapse-related symptoms. Those with high body weight (>65 kg) and younger women (<60 years) were associated with an increase in the risk for both anatomical and functional recurrence. Advanced preoperative prolapse (grade III-IV) of any compartment was associated with anatomical failure but not with symptomatic recurrence. There was a poor correlation between anatomical and symptomatic recurrence. Younger women and those with a higher body weight are more likely to experience recurrent prolapse after vaginal repair.


Subject(s)
Uterine Prolapse/etiology , Uterine Prolapse/pathology , Vagina/surgery , Adult , Aged , Aged, 80 and over , Female , Follow-Up Studies , Humans , Middle Aged , Recurrence , Risk Factors , Time Factors , Uterine Prolapse/epidemiology
9.
J Colloid Interface Sci ; 267(2): 265-71, 2003 Nov 15.
Article in English | MEDLINE | ID: mdl-14583201

ABSTRACT

Neutron diffraction and isotopic labeling have been used to determine the distribution of toluene sorbed into the interlamellar space of complexes of vermiculite with alkyl trimethylammonium bromide complex of alkyl chain lengths C(12), C(14), and C(16) and in a mixed C(12)/C(16) complex. The toluene remains in a liquid-like form and fills and swells the interlamellar space space up to a point where there remains a small amount of overlap of the alkyl chains of the surfactant. If the complex is between vermiculite and one surfactant only this results in the toluene concentration being reduced in the center of the interlamellar space, with maxima on either side. On the other hand, in a complex of mixed-length surfactants, the toluene distribution reaches its maximum at the center of the interlamellar space.

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