ABSTRACT
The application of a novel monitoring technique, based on the use of acoustic emissions, is reported for a model high shear granulation process. It has been demonstrated that this technique is capable of monitoring changes in physical properties of powder material during granulation (particle size, flow properties and compression properties). The technique is non-invasive, sensitive and relatively inexpensive.
Subject(s)
Acoustics , Powders/chemical synthesis , Tablets/chemical synthesis , Chemistry, Pharmaceutical , Compressive Strength , Particle Size , Sound Spectrography/methodsABSTRACT
A simple microprocessor-based data-acquisition system is presented that is capable of acquiring replicate integrated signal values and logging them to a serial data terminal.
ABSTRACT
A simple equation is presented that can be used to predict the improvement in bit-resolution that can be obtained by digital signal averaging in the presence of added random noise.