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1.
Psychiatr Serv ; 75(5): 492-495, 2024 May 01.
Article in English | MEDLINE | ID: mdl-38291887

ABSTRACT

Verbal mistreatment of staff by patients is common in health care settings. Experiencing or witnessing mistreatment can have harmful psychological impacts, affecting well-being and clinical practice. As part of an effort to become an antiracist organization, an academic community mental health center based in Connecticut developed an initiative to address verbal mistreatment. Training in the Expect, Recognize, Address, Support, Establish (ERASE) framework was provided to 140 staff members. This training and subsequent actions to enhance the culture of safety were perceived as helpful by staff. Further development of the initiative is proceeding as the center's primary performance improvement program.


Subject(s)
Community Mental Health Centers , Humans , Connecticut , Professional-Patient Relations , Health Personnel/psychology , Organizational Culture
2.
ACS Biomater Sci Eng ; 6(3): 1449-1461, 2020 03 09.
Article in English | MEDLINE | ID: mdl-33455378

ABSTRACT

The brain machine interface (BMI) describes a group of technologies capable of communicating with excitable nervous tissue within the central nervous system (CNS). BMIs have seen major advances in recent years, but these advances have been impeded because of a temporal deterioration in the signal to noise ratio of recording electrodes following insertion into the CNS. This deterioration has been attributed to an intrinsic host tissue response, namely, reactive gliosis, which involves a complex series of immune mediators, resulting in implant encapsulation via the synthesis of pro-inflammatory signaling molecules and the recruitment of glial cells. There is a clinical need to reduce tissue encapsulation in situ and improve long-term neuroelectrode functionality. Physical modification of the electrode surface at the nanoscale could satisfy these requirements by integrating electrochemical and topographical signals to modulate neural cell behavior. In this study, commercially available platinum iridium (Pt/Ir) microelectrode probes were nanotopographically functionalized using femto/picosecond laser processing to generate laser-induced periodic surface structures (LIPSS). Three different topographies and their physical properties were assessed by scanning electron microscopy and atomic force microscopy. The electrochemical properties of these interfaces were investigated using electrochemical impedance spectroscopy and cyclic voltammetry. The in vitro response of mixed cortical cultures (embryonic rat E14/E17) was subsequently assessed by confocal microscopy, ELISA, and multiplex protein array analysis. Overall LIPSS features improved the electrochemical properties of the electrodes, promoted cell alignment, and modulated the expression of multiple ion channels involved in key neuronal functions.


Subject(s)
Astrocytes , Neuroglia , Animals , Iridium , Lasers , Microelectrodes , Rats
3.
Am J Addict ; 21 Suppl 1: S56-62, 2012 Nov.
Article in English | MEDLINE | ID: mdl-23786512

ABSTRACT

BACKGROUND AND OBJECTIVES: Although higher levels of dispositional optimism are associated with decreased levels of psychopathology and pain, and higher levels of mental health functioning-important outcomes in opioid treatment programs-a paucity of studies has examined dispositional optimism among individuals with opioid use disorders. The aim of this study was to examine the clinical correlates (i.e., psychopathology, pain status) of dispositional optimism in opioid dependent patients enrolled in methadone maintenance treatment (MMT). METHODS: A survey targeting demographics, pain, psychopathology, and dispositional optimism was administered to 150 MMT patients. RESULTS: In multivariable analyses, higher levels of dispositional optimism were significantly associated with lower levels of: depression, screened personality disorder criteria, screened symptoms of posttraumatic stress disorder, and pain-related emotional strain. In comparison to those without a history of chronic pain (ie, noncancer related physical pain lasting at least 3 months), MMT patients who reported either lifetime or current chronic pain exhibited significantly lower levels of dispositional optimism. CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE: The associations among higher levels of dispositional optimism, lower levels of psychopathology, and lower pain-related emotional strain suggest that research focusing on the efficacy of specific interventions to promote dispositional optimism in MMT patients is warranted.


Subject(s)
Attitude , Chronic Pain/psychology , Mental Disorders/psychology , Opiate Substitution Treatment/psychology , Opioid-Related Disorders/psychology , Personality , Adult , Analgesics, Opioid/therapeutic use , Depressive Disorder/psychology , Female , Health Status , Humans , Male , Methadone/therapeutic use , Middle Aged , Multivariate Analysis , Opioid-Related Disorders/drug therapy , Personality Disorders/psychology , Stress Disorders, Post-Traumatic/psychology , Young Adult
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