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Clin Transl Oncol ; 10(5): 298-9, 2008 May.
Article in English | MEDLINE | ID: mdl-18490248

ABSTRACT

Rituximab is a treatment option to non-Hodg kin's diffuse large B-cell lymphoma (NHDLBCL) in advanced stage and comorbility. It is known the cardiotoxicity effect of this drug, but there is no previous report describing a complete atrioventricular block (CAVB) secundary to treatment with Rituximab. We present an elderly woman treated with monotherapy with Rituximab who experienced a CAVB after administration of the fifth dose of this drug.


Subject(s)
Antibodies, Monoclonal/adverse effects , Antineoplastic Agents/adverse effects , Atrioventricular Block/chemically induced , Lymphoma, Large B-Cell, Diffuse/drug therapy , Aged, 80 and over , Antibodies, Monoclonal, Murine-Derived , Dyslipidemias/complications , Female , Humans , Lymphoma, Large B-Cell, Diffuse/physiopathology , Rituximab , Spinal Osteophytosis/complications , Stroke/complications , Venous Thrombosis/complications
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