ABSTRACT
A 43-year-old man was admitted to the intensive care unit and diagnosed with yellow fever. He presented with refractory bleeding, extreme hyperferritinemia, and multiple organ dysfunction syndrome, requiring renal replacement therapy, mechanical ventilation, and treatment with vasoactive drugs. Because the bleeding did not respond to fresh-frozen plasma administration, the patient received therapeutic plasma exchange, which was accompanied by a marked improvement of the clinical and biochemical parameters, including a significant decline in serum ferritin levels
Subject(s)
Humans , Male , Adult , Yellow FeverABSTRACT
A 43-year-old man was admitted to the intensive care unit and diagnosed with yellow fever. He presented with refractory bleeding, extreme hyperferritinemia, and multiple organ dysfunction syndrome, requiring renal replacement therapy, mechanical ventilation, and treatment with vasoactive drugs. Because the bleeding did not respond to fresh-frozen plasma administration, the patient received therapeutic plasma exchange, which was accompanied by a marked improvement of the clinical and biochemical parameters, including a significant decline in serum ferritin levels.
Subject(s)
Iron Metabolism Disorders/diagnosis , Iron Metabolism Disorders/therapy , Plasma Exchange , Yellow Fever/complications , Yellow Fever/diagnosis , Adult , Hemorrhage , Humans , Intensive Care Units , Male , Multiple Organ Failure/therapy , Sepsis/therapyABSTRACT
OBJETIVO: Avaliar a prevalência da coexistência entre tireoidite de Hashimoto em casos de carcinoma papilífero de tireoide. MATERIAL E MÉTODOS: Foi realizado um estudo retrospectivo a partir dos arquivos eletrônicos do Centro de Patologia de Curitiba Hospital Nossa Senhora das Graças Curitiba, PR, no qual foram analisados 139 laudos histopatológicos de pacientes submetidos a tireoidectomia com diagnóstico de carcinoma papilífero de tireoide, do período de dezembro de 2010 a maio de 2013. RESULTADOS: Os resultados mostraram uma prevalência do gênero feminino (80,6%) e uma média de idade dos pacientes de 43,5. A variante de carcinoma papílifero mais frequente foi o tipo clássico (47,5%) e a que foi mais associada com tireoidite de Hashimoto foi o tipo microcarcinoma (55%). CONCLUSÃO: A prevalência de tireoidite de Hashimoto entre pacientes com carcinoma papilífero foi de 39,6%, a mesma ocorreu mais em mulheres, a média de idade foi de 43,5 anos e o subtipo histológico de carcinoma papilar mais associado foi o microcarcinoma
AIM: To evaluate prevalence of Hashimoto's thyroiditis in cases of papillary thyroid carcinoma. MATERIAL AND METHODS: We conducted a retrospective study from the electronic files of the Centro de Patologia de Curitiba Hospital Nossa Senhora das Graças - Curitiba, PR, analyzing 139 histopathological examinations of patients who were submitted by a thyroidectomy diagnosed with papillary thyroid carcinoma, from the time of December's 2010 to May´s 2013. RESULTS: The result has shown a prevalence of the female gender (80.6%), and an average age of 43.5. The papillary carcinoma variant of higher frequency was the classic type (47.5%), and the microcarcinoma type was the more associated (55%) with the Hashimoto´s thyroiditis. CONCLUSIONS: The prevalence of Hashimoto's thyroiditis in patients with papillary carcinoma was 39.6%, it was more in females, the average age was 43.5 years and the histological subtype of papillary carcinoma was the most associated is the microcarcinoma