ABSTRACT
Ureteral amyloidosis is an uncommon disease. It usually presents as an ureteral stenosis and resembles ureteral malignancy. The lesion consists of localized amyloidosis, containing lambda light chains, the etiology of which remains unknown. Ureteral calcifications have been suggested to be pathognomonic. When the diagnosis of ureteral amyloidosis is considered preoperatively, a renal-sparing surgery must be planned. We observed a case of bilateral ureteral amyloidosis presenting with anuria; the patient was treated with conservative surgery and colchicine. The renal function improved without recurrence and remained stable after 5 years of follow-up.
Subject(s)
Amyloidosis/complications , Anuria/etiology , Ureteral Diseases/complications , Aged , Amyloidosis/diagnosis , Amyloidosis/therapy , Combined Modality Therapy , Diagnostic Imaging , Female , Humans , Ureteral Diseases/diagnosisABSTRACT
A 19 year old girl working as a hairdresser developed a severe anemia due to occult pulmonary hemorrhage followed by anti-GBM glomerulonephritis with normal renal function. Withdrawal of the suspected toxic factor, products used for permanent waving, was followed by both clinical remission and disappearance of linear deposits of immunoglobin from the renal glomeruli. Anti-GBM antibodies were only detected in the serum after clinical healing. In a case of mild Goodpasture, careful search for a toxin and its withdrawal may be the first therapeutic step.