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1.
BMJ Case Rep ; 17(2)2024 Feb 27.
Article in English | MEDLINE | ID: mdl-38417936

ABSTRACT

Reed's syndrome (RS) is a rare autosomal-dominant disorder characterised by multiple cutaneous and uterine leiomyomas, with a strong tendency for renal cell carcinoma (RCC) development. A woman in her 50s, who had previously undergone total abdominal hysterectomy due to multiple uterine leiomyomas, presented with painful nodules on her trunk and right arm for the past 6 years. These nodules were confirmed as leiomyomas through histopathology. Diagnosis of RS was established through clinicopathological correlation and positive family history, particularly her mother's. Early-onset uterine leiomyomas in patients with a similar family history should raise suspicion for RS, necessitating vigilant long-term follow-up. RCC detection requires mandatory renal imaging. Screening family members and providing genetic counselling are crucial.


Subject(s)
Carcinoma, Renal Cell , Kidney Neoplasms , Leiomyomatosis , Neoplastic Syndromes, Hereditary , Skin Neoplasms , Uterine Neoplasms , Female , Humans , Carcinoma, Renal Cell/genetics , Uterine Neoplasms/diagnostic imaging , Uterine Neoplasms/surgery , Leiomyomatosis/diagnostic imaging , Leiomyomatosis/surgery , Skin Neoplasms/diagnosis , Skin Neoplasms/surgery , Skin Neoplasms/genetics , Neoplastic Syndromes, Hereditary/diagnosis , Neoplastic Syndromes, Hereditary/surgery , Neoplastic Syndromes, Hereditary/pathology , Kidney Neoplasms/genetics , Fumarate Hydratase/genetics
2.
Oman Med J ; 37(4): e411, 2022 Jul.
Article in English | MEDLINE | ID: mdl-36052107
4.
Indian Pediatr ; 59(1): 91, 2022 Jan 15.
Article in English | MEDLINE | ID: mdl-35060490

Subject(s)
Anetoderma , Humans , Skin
8.
Paediatr Child Health ; 26(5): 268-269, 2021 Aug.
Article in English | MEDLINE | ID: mdl-34336052
9.
10.
Oman Med J ; 36(2): e253, 2021 Mar.
Article in English | MEDLINE | ID: mdl-33936780
11.
Eur J Dermatol ; 31(1): 135-137, 2021 Feb 01.
Article in English | MEDLINE | ID: mdl-33772525
12.
Pediatr Dermatol ; 38(3): 701-703, 2021 May.
Article in English | MEDLINE | ID: mdl-33742484

ABSTRACT

Pityriasis rosea (PR) is a common papulosquamous disorder that may be related to primary infection or endogenous reactivation of human herpesvirus 7 and 6. Based on morphology, distribution, and size of lesions, several atypical variants of PR have been described. PR following the lines of Blaschko represents an atypical variant that has seldom been described in the literature. Here, we describe a child with diabetes who developed PR in a symmetrical, blaschkolinear configuration.


Subject(s)
Herpesvirus 7, Human , Pityriasis Rosea , Child , Family , Humans , Pityriasis Rosea/diagnosis
19.
Urology ; 147: 33-34, 2021 01.
Article in English | MEDLINE | ID: mdl-33148435

ABSTRACT

Papulonecrotic tuberculid represents a hypersensitivity reaction to Mycobacterium tuberculosis or its products that disseminate through hematogenous route to the skin from an internal tuberculous focus. It is characterized by recurrent eruptions of asymptomatic, dusky red papules, which undergo ulceration and crusting, and eventually heal after a few weeks with varioliform scarring. Although it most commonly involves extragenital sites, isolated glans penis involvement has been reported very rarely.


Subject(s)
Antitubercular Agents/therapeutic use , Penis/microbiology , Tuberculosis, Cutaneous/diagnosis , Ulcer/diagnosis , Ulcer/drug therapy , Adult , Cicatrix , Diagnosis, Differential , Humans , Male , Mycobacterium tuberculosis , Necrosis/pathology , Penis/pathology , Recurrence , Skin/pathology , Tuberculosis, Cutaneous/microbiology , Tuberculosis, Cutaneous/pathology , Ulcer/microbiology
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