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1.
Phys Rev Lett ; 132(12): 126903, 2024 Mar 22.
Article in English | MEDLINE | ID: mdl-38579224

ABSTRACT

Adiabaticity is crucial for our understanding of complex quantum dynamics and thus for advancing fundamental physics and technology, but its impact cannot yet be quantified in complex but common cases where dynamics is only partially adiabatic, several eigenstates are simultaneously populated and transitions between noneigenstates are of key interest. We construct a universally applicable measure that can quantify the adiabaticity of quantum transitions in an arbitrary basis. Our measure distinguishes transitions that occur due to the adiabatic change of populated system eigenstates from transitions that occur due to beating between several eigenstates and can handle nonadiabatic events. While all quantum dynamics fall within the scope of the measure, we demonstrate its usage and utility through two important material science problems-energy and charge transfer-where adiabaticity could be effected by nuclear motion and its quantification will aid not only in unraveling mechanisms but also in system design, for example, of light harvesting systems.

2.
Curr Pharm Des ; 15(31): 3681-96, 2009.
Article in English | MEDLINE | ID: mdl-19925420

ABSTRACT

LIM (Lin-11, Isl-1, Mec-3), RING (Really interesting new gene), PHD (Plant homology domain) and MYND (myeloid, Nervy, DEAF-1) domains are all zinc-binding domains that ligate two zinc ions. Unlike the better known classical zinc fingers, these domains do not bind DNA, but instead mediate interactions with other proteins. LIM-domain containing proteins have diverse functions as regulators of gene expression, cell adhesion and motility and signal transduction. RING finger proteins are generally associated with ubiquitination; the presence of such a domain is the defining feature of a class of E3 ubiquitin protein ligases. PHD proteins have been associated with SUMOylation but most recently have emerged as a chromatin recognition motif that reads the methylation state of histones. The function of the MYND domain is less clear, but MYND domains are also found in proteins that have ubiquitin ligase and/or histone methyltransferase activity. Here we review the structure-function relationships for these domains and discuss strategies to modulate their activity.


Subject(s)
DNA-Binding Proteins/physiology , Homeodomain Proteins/physiology , Zinc Fingers/physiology , Animals , Binding Sites , DNA-Binding Proteins/chemistry , Homeodomain Proteins/chemistry , Humans , Protein Conformation , Protein Folding , RING Finger Domains/physiology , Sequence Homology, Amino Acid
3.
Internet resource in English | LIS -Health Information Locator | ID: lis-34420

ABSTRACT

El artículo investiga el efecto de la ansiedad dental y hábitos de visitas al odontólogo, así como diversas variables sociodemográficas en calidad de vida relacionada con la salud oral. El estudio se realizó en sujetos de 15 a 54 años que viven en Udaipur, distrito de India.Los mejores predictores de ansiedad dental resultaron en orden descendente: ocupación, género, y educación. La ocupación (Profesionales) fue el mejor predictor para la ansiedad dental con una varianza de 6.8 porciento.


Subject(s)
29161 , Habits , India , Dental Anxiety
4.
Schizophr Res ; 99(1-3): 312-23, 2008 Feb.
Article in English | MEDLINE | ID: mdl-18155880

ABSTRACT

Verbal fluency deficits in schizophrenia are difficult to interpret because the tasks are multi-factorial and groups differ in total words generated. We manipulated retrieval and switching demands by requiring alternation between over-learned sequences in which retrieval is relatively automatic (OS) and semantic categories requiring increased retrieval effort (SC). Controlled processing was also manipulated by including switching and non-switching conditions, and formal thought disorder (FTD) was assessed with the communication disorders index (CDI). The OS/SC semantic fluency paradigm was administered during fMRI to 13 patients with schizophrenia and 14 matched controls. Images were acquired on a 3 Tesla Siemens scanner using compressed image acquisition to allow for cued overt word production. Subjects alternated between OS, SC, OS-switch, SC-switch, and baseline blocks. Images were pre-processed in SPM-2, and a two-stage random effects analysis tested within and between group contrasts. There were no group performance differences. fMRI analysis did not reveal any group differences during the OS non-switching condition. Both groups produced expected activation in bilateral prefrontal and inferior parietal regions. However, during the SC condition patients had greater activation than controls in left prefrontal, right anterior cingulate, right superior temporal, bilateral thalamus, and left parietal regions. There was also evidence of patient over-activation in prefrontal, superior temporal, superior parietal, and visual association areas when a switching component was added. FTD was negatively correlated with BOLD response in the right anterior cingulate, cuneus and superior frontal gyrus during increased retrieval demand, and positively correlated with fMRI activation in the left lingual gyrus, right fusiform gyrus and left superior parietal lobule during increased switching demand. These results indicate that patients are able to successfully perform effortful semantic fluency tasks during non-speeded conditions. When retrieval is relatively automatic there does not appear to be an effect of schizophrenia on fMRI response. However, when retrieval and controlled processing demands increase, patients have greater activation than controls despite unimpaired task performance. This inefficient BOLD response may explain why patients are slower and less accurate on standard self-paced fluency tasks.


Subject(s)
Arousal/physiology , Attention/physiology , Brain/physiopathology , Image Processing, Computer-Assisted , Imaging, Three-Dimensional , Magnetic Resonance Imaging , Mental Recall/physiology , Schizophrenia/physiopathology , Schizophrenic Psychology , Semantics , Verbal Behavior/physiology , Adult , Brain Mapping , Cerebral Cortex/physiopathology , Cognition Disorders/diagnosis , Cognition Disorders/physiopathology , Cognition Disorders/psychology , Dominance, Cerebral/physiology , Female , Humans , Male , Nerve Net/physiopathology , Schizophrenia/diagnosis , Speech Production Measurement , Thinking/physiology
5.
Bioresour Technol ; 96(9): 1019-28, 2005 Jun.
Article in English | MEDLINE | ID: mdl-15668198

ABSTRACT

Increasing demand for fodder and fuelwood and the scarcity of a good quality water in arid areas has resulted in a search for an alternative source of water for biomass production. An experiment utilizing municipal effluent in growing Dalbergia sissoo was conducted. Five treatments included T1, municipal effluent at 1 PET (Potential evapo-transpiration) (without plant); T2, municipal effluent at 1/2 PET; T3, municipal effluent at 1PET; T4, municipal effluent at 2 PET; and T5, canal water at 1 PET. Observations included plant height, collar diameter at one-month intervals and plant mineral composition, mineral uptake and changes in soil properties at 24 months of plant age. Application of municipal effluent produced better growth in D. sissoo seedlings. Concentrations of nitrogen (N), phosphorus (P), potassium (K), calcium (Ca), magnesium (Mg), copper (Cu), iron (Fe), manganese (Mn) and zinc (Zn) were greater in seedlings irrigated with municipal effluent than those of the seedlings irrigated by the treatment T5, and positively related with the quantity of irrigation. The concentrations were greatest in foliage compared to the other parts of seedling, with the exception of Cu concentration. Application of municipal effluents resulted in a 2- to 3-fold increase in the concentrations of soil K, Cu, Fe, Mn and Zn, whereas NH4-N and PO4-P availability increased by 8.1- and 4.5-fold, respectively. The increase in soil organic carbon was only observed in treatments T3 and T4. The accumulations of soil NO3-N, Na, Cu, Fe, Mn and Zn were more in lower soil layers but the other soil parameters showed their greatest values in the upper soil layer. Irrigation using municipal effluent did not result in toxicity to the seedlings before the age of 24 months. The results suggest that municipal effluent could be utilized, as an important source of water and nutrients in growing D. sissoo to increase biomass production in the needs of suburban dwellers. However, a preliminary treatment to reduce excess NH4-N and PO4-P will be required before application to the plantation.


Subject(s)
Dalbergia/chemistry , Dalbergia/growth & development , Desert Climate , Sewage/chemistry , Soil/analysis , Waste Disposal, Fluid/methods , Water Supply , Agriculture/methods , Biomass , Cities , Conservation of Natural Resources , India
6.
Bioresour Technol ; 88(3): 221-8, 2003 Jul.
Article in English | MEDLINE | ID: mdl-12618044

ABSTRACT

Effects of mixed industrial effluents on growth, dry matter accumulation and mineral nutrient in Eucalyptus camaldulensis seedlings were studied. The objective was to evaluate the adaptability of E. camaldulensis to effluent, tolerance to excess/deficiency of mineral elements and ultimately to determine suitable combinations of industrial/municipal effluent for their use in biomass production in dry areas. Different irrigation treatments were: T(1): good water; T(2): municipal effluent; T(3): textile effluent; T(4): steel effluent; T(5): textile effluent+municipal effluent in 1:1 ratio; T(6): steel effluent+municipal effluent in 1:2 ratio; T(7): steel+textile+municipal effluent in 1:2:2 ratio; and T(8): steel+textile effluent in 1:2 ratio. High concentrations of metal ions and low concentrations of Ca, Mg, K, Na, N and P in soil and seedlings of T(4) resulted in mortality of the seedlings within a few days. Addition of the textile/municipal effluent increased the survival time of the seedlings for two to three months in T(6), T(7) and T(8) treatments. Among the remaining treatments, the seedlings of T(2) attained 131 cm height, 1.97 cm collar diameter, 19 total branches and produced 158 g seedling(-1) of dry biomass at the age of 10 months. The seedling of T(3) produced the least growth and biomass. Growth equivalent to that of the seedlings of T(1) treatment was achieved when municipal effluent was mixed with textile effluent (T(5)). There was a decrease in soil pH, EC, SOC, NH(4)-N, NO(3)-N, PO(4)-P and basic cations and increase in the concentration of Cu, Fe, Mn and Zn with T(4) treatment. The reverse trend was observed in T(3) where a high concentration of Na might have reduced Mg and micronutrient concentration in seedlings potentially affecting root and leaf growth. Mixing of effluents may be useful in tree irrigation to increase biomass productivity, which is evidenced by improved growth in T(5) and survival in T(6), T(7) and T(8) treatments. Further, reduction of toxic concentration of metal ions in effluents may be helpful for a long-term field application.


Subject(s)
Eucalyptus/metabolism , Metals/metabolism , Minerals/metabolism , Seedlings/metabolism , Water Pollutants/metabolism , Biomass , Eucalyptus/chemistry , Eucalyptus/growth & development , Industry , Plant Leaves/growth & development , Plant Roots/growth & development , Plant Shoots/growth & development , Seedlings/chemistry , Seedlings/growth & development , Water/chemistry
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