Acutely Normalizing Walking Speed Does Not Normalize Gait Biomechanics Post-Anterior Cruciate Ligament Reconstruction.

PURPOSE: To determine the effect of acutely increasing walking speed on gait biomechanics in ACLR individuals compared with their habitual speed and uninjured matched-controls. METHODS: Gait biomechanics were collected on 30 ACLR individuals (20 females; age, 22.0 ± 4.2 yr; body mass index, 24.0 ± 3.0 kg·m -2 ) at their habitual speed and at 1.3 m·s -1 , a speed similar to controls, and 30 uninjured matched-controls (age: 21.9 ± 3.8, body mass index: 23.6 ± 2.5) at their habitual speed. Functional waveform analyses compared biomechanics between: i) walking at habitual speed vs 1.3 m·s -1 in ACLR individuals; and ii) ACLR individuals at 1.3 m·s -1 vs controls. RESULTS: In the ACLR group, there were no statistically significant biomechanical differences between walking at habitual speed (1.18 ± 0.12 m·s -1 ) and 1.3 m·s -1 (1.29 ± 0.05 m·s -1 ). Compared with controls (habitual speed: 1.34 ± 0.12 m·s -1 ), the ACLR group while walking at 1.3 m·s -1 exhibited smaller vertical ground reaction force (vGRF) during early and late stance (13-28, 78-90% stance phase), greater midstance vGRF (47-61%), smaller early-to-midstance knee flexion angle (KFA; 1-44%), greater mid-to-late stance KFA (68-73, 96-101%), greater internal knee abduction moment (69-101%), and smaller internal knee extension moment (4-51, 88-96%). CONCLUSIONS: Increasing walking speed to a speed similar to uninjured controls did not elicit significant changes to gait biomechanics, and ACLR individuals continued to demonstrate biomechanical profiles that are associated with PTOA development and differ from controls.

Psychological Readiness, Injury-Related Fear, and Persistent Knee Symptoms After Anterior Cruciate Ligament Reconstruction.

CONTEXT: Poor psychological responses after anterior cruciate ligament reconstruction (ACLR) have been associated with a failure to return to sport and increased secondary injury risk. However, we do not know whether poor psychological responses after ACLR influence patient-reported knee function and knee symptoms. OBJECTIVE: To examine the association between psychological factors (ie, psychological readiness and injury-related fear) and the presence of persistent knee symptoms in individuals 6 to 12 months after ACLR. DESIGN: Cross-sectional study. SETTING: Research laboratory. PATIENTS OR OTHER PARTICIPANTS: In total, 101 participants, aged 13 to 25 years old, between 6 and 12 months after primary unilateral ACLR were enrolled in the study. MAIN OUTCOME MEASURE(S): Persistent knee symptoms were identified using an established criterion based on the subscales of the Knee injury and Osteoarthritis Outcome Score. Participants also completed the Anterior Cruciate Ligament-Return to Sport after Injury (ACL-RSI) and the Tampa Scale of Kinesiophobia-11 (TSK-11) to assess psychological readiness and injury-related fear, respectively. Higher ACL-RSI scores indicate higher psychological readiness, and higher TSK-11 scores indicate higher injury-related fear. RESULTS: Twenty-nine participants (29%) met the criteria for persistent knee symptoms. For every 1 SD lower in the ACL-RSI score, participants had 2.1 times greater odds of persistent knee symptoms after ACLR (95% CI = 1.3, 3.6). For every 1 SD higher in the TSK-11 score, participants had 1.9 times greater odds of persistent knee symptoms after ACLR (95% CI = 1.1, 3.3). Both the ACL-RSI and TSK-11 were considered good at classifying persistent knee symptoms, as the areas under the curve were 0.78 and 0.73, respectively. CONCLUSIONS: Individuals with a lower level of psychological readiness and more injury-related fear after ACLR had greater odds of persistent knee symptoms. Overall, these results highlight the potential clinical benefit of a comprehensive, biopsychosocial approach to managing health and wellness for individuals after ACLR.

Psychological Readiness and Injury-Related Fear are Associated with Persistent Knee Symptoms after ACL Reconstruction.

CONTEXT: Poor psychological responses after anterior cruciate ligament reconstruction (ACLR) have been associated with failure to return to sport and increased secondary injury risk. However, we do not know whether poor psychological responses after ACLR influence patient-reported knee function and knee symptoms. OBJECTIVE: To examine the association between psychological factors (i.e., psychological readiness and injury-related fear) and the presence of persistent knee symptoms in individuals 6-12 months after ACLR. DESIGN: Cross-Sectional. SETTING: Research Laboratory. PATIENTS OR OTHER PARTICIPANTS: One-hundred and two participants, ages 13-25 years old, between 6 and 12 months post primary, unilateral ACLR were enrolled in the study. INTERVENTIONS(S): Persistent knee symptoms was identified using an established criterion based on the subscales of the Knee Injury and Osteoarthritis Outcome Score. MAIN OUTCOME MEASURE(S): Participants also completed the Anterior Cruciate Ligament-Return to Sport after Injury (ACL-RSI) and the Tampa Scale of Kinesiophhobia-11 (TSK-11) to assess psychological readiness and injury-related fear, respectfully. Higher ACL-RSI scores indicate higher psychological readiness and higher TSK-11 scores indicate higher injury-related fear. RESULTS: Seventy participants (69%) met the criteria for persistent knee symptoms. For every standard deviation (SD) lower in ACL-RSI, a participants had 8.6 times greater odds of having persistent knee symptoms after ACLR (CI95: 3.3, 22.4). For every SD higher in TSK-11, a participants had 3.9 times greater odds of having persistent knee symptoms after ACLR (CI95: 2.1, 7.4). Both the ACL-RSI and TSK-11 were considered "good" at classifying persistent knee symptoms as areas under the curve were 0.88 and 0.83, respectfully. CONCLUSIONS: Individuals with lower psychological readiness and higher injury-related fear after ACLR have greater odds of experiencing persistent knee symptoms. Overall, these results highlight the potential clinical benefit for a comprehensive, biopsychosocial approach to managing health and wellness for individuals after ACLR.

Kinesiophobia Is Associated with Peak Knee Abduction Angle during Jump Landing after ACL Reconstruction.

INTRODUCTION: This study aimed to investigate the associations between kinesiophobia, knee abduction angle (KAA) during the first 100 ms of landing, and knee flexion excursion (KFE) in individuals 5-12 months after anterior cruciate ligament reconstruction (ACLR). We hypothesized that greater kinesiophobia would be associated with greater peak KAA and lesser KFE during landing on the ACLR limb, but not on the contralateral limb. METHODS: Thirty-six participants between 14 and 35 yr old (females = 19, age = 19.9 ± 5.1 yr, height = 172.5 ± 9.4 cm, weight = 76.7 ± 20.0 kg, time since surgery =7.2 ± 1.7 months) were recruited from a sports medicine clinic at 5-12 months after primary unilateral ACLR. Participants completed the Tampa Scale of Kinesiophobia-11 (TSK-11) to measure kinesiophobia and three successful trials of a standard drop vertical jump task. A 10-camera three-dimensional motion capture system synchronized with two embedded force plate platforms was used to capture jump-landing kinematics. Separate stepwise linear regression models were used to examine the associations between kinesiophobia, peak KAA, and KFE on the ACLR and contralateral limbs after accounting for time since surgery and biological sex. RESULTS: When accounting for time since surgery and biological sex, every 1-point increase on the TSK-11 (i.e., increase in kinesiophobia) associated with a 0.37° increase (i.e., a 7.1% increase) in ACLR limb KAA ( P = 0.02). Kinesiophobia was not associated with contralateral limb KAA, ACLR limb KFE, or contralateral limb KFE. CONCLUSIONS: Higher kinesiophobia was related to greater amounts of peak KAA during landing in individuals 5-12 months post-ACLR. Modifying kinesiophobia may help to decrease KAA and lead to reduced secondary ACL injury risk. Future research should investigate feasible psychological interventions to reduce kinesiophobia and improve KAA in patients post-ACLR.

Age-, Sex-, and Graft-Specific Reference Values From 783 Adolescent Patients at 5 to 7 Months After ACL Reconstruction: IKDC, Pedi-IKDC, KOOS, ACL-RSI, Single-Leg Hop, and Thigh Strength.

OBJECTIVE: To describe age-, sex-, and graft source-specific reference values for patient-reported, physical function, and strength outcome measures in adolescents at 5 to 7 months after anterior cruciate ligament reconstruction. DESIGN: Cross-sectional study. METHODS: Data were collected at 3 universities and 2 children's hospitals. The participants completed at least one of the International Knee Documentation Committee (IKDC) Subjective Evaluation Form, Pediatric IKDC (Pedi-IKDC), Knee Injury and Osteoarthritis Outcomes Score (KOOS), and Anterior Cruciate Ligament Return to Sport After Injury (ACL-RSI) Scale. Participants also completed single-leg hop tests and/or isokinetic quadriceps and hamstrings strength assessments (at 60°/s). Reference values were summarized using descriptive statistics and stratified for age, sex, and graft source. RESULTS: Reference values were reported for common patient-reported outcomes and measures of physical function and strength from 783 participants (56% females, age = 16. 4 ± 2.0 years) who were in early adolescence (12-14 years, N = 183, 52% females), middle adolescence (15-17 years, N = 456, 58% females), or late adolescence (18-20 years, N = 144, 55% females). Three hundred seventy-nine participants (48.4%) received a bone-patellar tendon-bone autograft, 292 participants (37.3%) received hamstring tendon autograft, and 112 participants (14.3%) received autograft or allograft from an alternative source. CONCLUSION: Reference values for common patient-reported outcomes and measures of physical function and strength differed depending on a patient's age, sex, and graft source. Using patient-specific reference values, in addition to previously described age-appropriate cutoff values, may help clinicians monitor and progress patients through rehabilitation and return to physical activity after anterior cruciate ligament reconstruction. J Orthop Sports Phys Ther 2023;53(4):1-8. Epub: 23 January 2023. doi:10.2519/jospt.2023.11389.

Quadriceps Strength and Knee-Related Symptom State 6 Months After Anterior Cruciate Ligament Reconstruction.

CONTEXT: Isometric quadriceps strength metrics and patient-reported outcomes are commonly used in return-to-sport assessments in those with anterior cruciate ligament reconstruction (ACLR). Patients may experience clinical knee-related symptoms aggravating enough to seek additional medical care after ACLR. In addition to seeking additional medical care, these patient-reported clinical knee-related symptoms may also influence function after ACLR. However, whether an association exists between these common quadriceps metrics and the patient-reported clinical knee-related symptom state is unknown. OBJECTIVE: To determine if meeting isometric quadriceps strength and symmetry criteria is associated with acceptable clinical knee-related symptoms at 5 to 7 months post-ACLR. DESIGN: Cross-sectional study. SETTING: Laboratories. PATIENTS OR OTHER PARTICIPANTS: We classified individuals at 5 to 7 months post-ACLR based on their isometric ACLR and uninvolved-limb quadriceps strength or quadriceps strength symmetry. We also dichotomized participants based on the Englund et al criteria for unacceptable clinical knee-related symptoms. MAIN OUTCOME MEASURE(S): Quadriceps strength variables were compared between groups using analysis of covariance, and the relative risk of a participant in each quadriceps strength group reporting acceptable clinical knee-related symptoms was determined using binary logistic regression. RESULTS: A total of 173 individuals participated. The isometric quadriceps strength and limb symmetry index were different (P < .001) between quadriceps strength groups. Those categorized as both strong and symmetric had a 1.28 (95% CI = 0.94, 1.74) and individuals categorized as symmetric only had a 1.29 (95% CI = 0.97, 1.73) times greater relative risk of reporting acceptable clinical knee-related symptoms compared with the neither strong nor symmetric group. CONCLUSIONS: The majority of individuals (85%) recovering from ACLR failed to meet either the clinical quadriceps strength or symmetry criteria at 5 to 7 months post-ACLR. Quadriceps strength and quadriceps strength symmetry are clinically important but may not be primary determinants of the clinical knee-related symptom state within the first 6 months post-ACLR.

A Comparison of Psychological Readiness and Patient-Reported Function Between Sexes After Anterior Cruciate Ligament Reconstruction.

CONTEXT: Postoperative functional and return-to-sport outcomes after anterior cruciate ligament reconstruction (ACLR) differ by sex. However, whether sex disparities are observed in patient-reported outcome measures (PROMs) before return to sport after ACLR is unclear. OBJECTIVES: To compare common PROMs between young men and women who had not yet returned to sport after ACLR. DESIGN: Cross-sectional study. SETTING: University laboratory. PATIENTS OR OTHER PARTICIPANTS: Forty-five young men (age = 18.7 ± 2.7 years, time since surgery = 6.8 ± 1.4 months) and 45 women matched for age (±1 year) and time since surgery (±1 month; age = 18.8 ± 2.8 years, time since surgery = 6.9 ± 1.4 months) with ACLR participated. MAIN OUTCOME MEASURE(S): Participants completed the Tegner Activity Scale, ACL Return to Sport After Injury scale, Tampa Scale of Kinesiophobia, International Knee Documentation Committee (IKDC) Subjective Knee Evaluation Score, and Knee Injury and Osteoarthritis Outcome Score (KOOS). The PROMs were compared between men and women using Mann-Whitney U tests. Odds ratios were calculated to evaluate the odds of a male reporting a PROM value above the previously established normative value as compared with a female. RESULTS: Sex differences were present for the IKDC score (P = .01) and KOOS Pain score (P = .04) but not for the Tegner Activity Scale (P = .22), ACL Return to Sport After Injury scale score (P = .78), Tampa Scale of Kinesiophobia score (P = .64), or other KOOS subscales (P values = .40 to .52). The odds of reporting values above normative levels differed only for the IKDC score (odds ratio = 2.72, 95% confidence interval = 1.16, 6.38). CONCLUSIONS: After ACLR, young men and women reported similar levels of knee-related function, fear of movement, and readiness for return to sport and were equally likely to meet clinically meaningful normative values before return to sport. Overreliance on patient reports or objective functional outcomes in evaluating patient progress and readiness for return to sport after ACLR may limit clinicians in their ability to comprehensively evaluate and develop individualized interventional approaches that optimize patient outcomes.

Thigh-Muscle and Patient-Reported Function Early After Anterior Cruciate Ligament Reconstruction: Clinical Cutoffs Unique to Graft Type and Age.

CONTEXT: Patient-reported function is an important outcome in anterior cruciate ligament rehabilitation. Identifying which metrics of thigh-muscle function are indicators of normal patient-reported function can help guide treatment. OBJECTIVE: To identify which metrics of thigh-muscle function discriminate between patients who meet and patients who fail to meet age- and sex-matched normative values for patient-reported knee function in the first 9 months after anterior cruciate ligament reconstruction (ACLR) and establish cutoffs for these metrics by covariate subgroups. DESIGN: Cross-sectional retrospective study. SETTING: Laboratory. PATIENTS OR OTHER PARTICIPANTS: A total of 256 patients (129 females, 128 males; age = 17.1 ± 3.0 years, height = 1.7 ± 0.1 m, mass = 74.1 ± 17.9 kg, months since surgery = 6.4 ± 1.4), 3 to 9 months after primary unilateral ACLR. MAIN OUTCOME MEASURE(S): We stratified the sample into dichotomous groups by the International Knee Documentation Committee (IKDC) score (IKDCMET, IKDCNOT MET) using sex- and age-matched normative values. We measured quadriceps and hamstrings isokinetic (60°/s) torque and power bilaterally. Normalized quadriceps and hamstrings peak torque (Nm/kg) and power (W/kg), limb symmetry indices (LSI, %), and hamstrings : quadriceps ratios were calculated. Logistic regression indicated which of these metrics could predict IKDC classification while controlling for age, graft type, and sex. Receiver operating characteristic curves established cutoffs for explanatory variables for both total cohort and covariate subgroups. Odds ratios (OR) determined the utility of each cutoff to discriminate IKDC status. RESULTS: Quadriceps torque LSI (≥69.4%, OR = 3.6), hamstrings torque (≥1.11 Nm/kg, OR = 2.1), and quadriceps power LSI (≥71.4%, OR = 2.0) discriminated between IKDC classification in the total cohort. Quadriceps torque LSI discriminated between IKDC classification in the patellar-tendon graft (≥61.6%, OR = 5.3), hamstrings-tendon graft (≥71.8%, OR = 10.5), and age <18 years (≥74.3%, OR = 5.2) subgroups. Hamstrings torque discriminated between IKDC classifications in the age <18 years (≥1.10 Nm/kg, OR = 2.6) subgroup. CONCLUSIONS: Quadriceps torque LSI, hamstrings torque, and quadriceps power LSI were the most useful metrics for predicting normal patient-reported knee function early after ACLR. Further, cutoff values that best predicted normal patient-reported function differed by graft type and age.

Quadriceps Muscle Size Following ACL Injury and Reconstruction: A Systematic Review.

Image-based assessments of quadriceps muscle size facilitate examination of structural changes after anterior cruciate ligament (ACL) injury and reconstruction (ACLR). Understanding the effects of ACLR on muscle size measures may aid in clarifying the contribution of quadriceps atrophy toward quadriceps strength. The purpose of this study was to systematically review the literature examining the effects of ACLR on quadriceps muscle volume and cross-sectional area (CSA). An online database search was conducted using Web of Science, SportDISCUS, PubMed (Medline), CINHAL (EBSCO), and Cochrane Library limited to articles published after January 1, 1980. Means and standard deviations were extracted for the ACLR limb and the contralateral limb, and sample characteristics from relevant articles. Magnitude of between limb differences were assessed using pooled effect sizes (Hedge's g) and 95% confidence intervals. Eleven articles (five CSA, six muscle volume) were included in this systematic review. Included studies reported negative effective sizes, indicating that the ACLR limb was smaller in CSA or muscle volume compared with the contralateral limb; however, 36% of the included articles reported meaningful difference between the limbs. Quadriceps atrophy may occur following ACL injury and persist after rehabilitation, however, the magnitude of these reductions may not be clinically meaningful and may only partially explain the persistent quadriceps weakness that is ubiquitous among this patient population. © 2019 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 38:598-608, 2020.

Associations between isometric quadriceps strength characteristics, knee flexion angles, and knee extension moments during single leg step down and landing tasks after anterior cruciate ligament reconstruction.

BACKGROUND: It is unclear of how peak knee extension torque and early rate of torque development outcomes are related to lower extremity loading and sagittal plane movement in activities of daily living and landing tasks despite consistent deficits after anterior cruciate ligament reconstruction. The purpose of this cross-section study is to assess the ability of quadriceps strength characteristics to predict movement patterns during a step down and single leg drop crossover hopping tasks. METHODS: Fifty-two individuals with a unilateral history of anterior cruciate ligament reconstruction completed three trials of the step down and crossover hopping tasks on their involved limb. Participants completed three isometric knee extension contractions at 90° knee flexion with visual feedback to assess peak knee extension torque and rate of torque development during the first 0-100 ms and 100-200 ms of the contraction. FINDINGS: Peak knee extension torque explained the greatest variance in peak knee extension moment (R2 = 40.4%, p < 0.001) and knee flexion angle (R2 = 46.7%, p < 0.001) during the crossover hop landing. Rate of torque development (0-100 ms) was the only predictor of knee flexion angle (R2 = 19.8%, p = 0.01) at initial contact during the crossover hopping landing. Rate of torque development (100-200 ms) explained 17.6% of the variance in peak knee extension moment during the step down (p = .03). INTERPRETATION: Peak knee extension torque and early rate of torque development outcomes demonstrate limited relationships between movement of activities of daily living and sport-specific tasks. These limitations should be considered when interpreting the results of isometric strength testing in a clinical setting.

Sex differences in quadriceps rate of torque development within 1 year of ACL reconstruction.

OBJECTIVES: To investigate the effect of sex on measures of quadriceps strength, rate of torque development, and knee function during the first year following ACLR. DESIGN: Cross-sectional; SETTING: University community; PARTICIPANTS: Sixty individuals (29 men) with unilateral ACLR in the last 12 months. MAIN OUTCOME MEASURES: Participants completed bilateral knee extension maximal voluntary isometric contraction (MVIC, Nm/kg) strength assessments. Rates of torque development (Nm*kg-1*s-1) were assessed from contraction initiation to 100 ms (RTD100) and from 100 ms to 200 ms after contraction initiation (RTD200). The effects of sex MVIC strength, RTD, and limb symmetry were assessed using separate ANCOVAs. RESULTS: Women displayed weaker involved limb (Men = 2.72 ±â€¯0.72 Nm*kg-1, Women = 2.01 ±â€¯0.50 Nm*kg-1, p < 0.001) and contralateral limb (Men = 3.15 ±â€¯0.52 Nm*kg-1, Women = 2.66 ±â€¯0.58 Nm*kg-1, p < 0.001) MVIC, and slower involved limb RTD100 (Men = 8.36 ±â€¯3.16 Nm*kg-1*s-1, Women = 6.50 ±â€¯2.41 Nm*kg-1*s-1, p = 0.01) and RTD200 (Men = 9.49 ±â€¯3.45 Nm*kg-1*s-1, Women = 9.49 ±â€¯3.45 Nm*kg-1*s-1, p < 0.001) when compared to men. CONCLUSIONS: Within the first year after ACLR, women displayed bilateral quadriceps weakness and slower involved limb quadriceps RTD when compared to men. Specific focus on facilitating quadriceps hypertrophy and improving neural drive to the quadriceps is indicated when treating female patients attempting to make a return to sport after ACLR.

Reactive Strength Index and Knee Extension Strength Characteristics Are Predictive of Single-Leg Hop Performance After Anterior Cruciate Ligament Reconstruction.

Birchmeier, T, Lisee, C, Geers, B, and Kuenze, C. Reactive strength index and knee extension strength characteristics are predictive of single-leg hop performance after anterior cruciate ligament reconstruction. J Strength Cond Res 33(5): 1201-1207, 2019-Single-leg hop distance is incorporated into return to sport criteria after anterior cruciate ligament reconstruction (ACLR) because of its relationship with knee extension strength; however, it may be related to other strength and plyometric characteristics. The purpose of this study was to assess the association between isometric knee extension strength and plyometric characteristics, including amortization and reactive strength index (RSI), measured during a single-leg drop vertical jump and single-leg hop performance in individuals with unilateral ACLR. Participants attended 2 testing sessions. During the first session, a biomechanical analysis using a 3D motion capture system was performed to measure RSI and amortization during a single-leg drop vertical jump for maximal height. Participants completed a single hop and a triple hop for maximal distance. During the second session, isometric knee extension strength was measured during a maximal voluntary isometric contraction. Strength characteristics included peak torque, rate of torque development (RTD), RTD 0-100 ms (RTD 100), and RTD 100-200 ms (RTD 200). Fifty-two individuals (17 men/35 women) participated. Multivariable regression models revealed jump height, peak torque, and RTD 200 explained 60.9% of the variance in normalized single-leg hop distance (p < 0.001). Reactive strength index, peak torque, RTD 200, and RTD 100 significantly explained 61.8% of the variance in normalized triple hop distance (p < 0.001). Single hop distance may indicate improved knee extension strength, whereas triple hop distance may indicate improvement in reactive strength. Training to improve RSI may improve triple hop performance and clinical outcomes in this population.

Quadriceps Strength and Volitional Activation After Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-analysis.

CONTEXT:: Quadriceps function is a significant contributor to knee joint health that is influenced by central and peripheral factors, especially after anterior cruciate ligament reconstruction (ACLR). OBJECTIVE:: To assess differences of unilateral quadriceps isometric strength and activation between the involved limb and contralateral limb of individuals with ACLR and healthy controls. DATA SOURCES:: Web of Science, SportDISCUS, PubMed, CINAHL, and the Cochrane Database were all used during the search. STUDY SELECTION:: A total of 2024 studies were reviewed. Twenty-eight studies including individuals with a unilateral history of ACLR, isometric knee extension strength normalized to body mass, and quadriceps activation measured by central activation ratios (CARs) through a superimposed burst technique were identified for meta-analysis. The methodological quality of relevant articles was assessed using a modified Downs and Black scale. Results of methodological quality assessment ranged from low to high quality (low, n = 10; moderate, n = 8; high, n = 10). STUDY DESIGN:: Meta-analysis. LEVEL OF EVIDENCE:: Level 2. DATA EXTRACTION:: Means, standard deviations, and sample sizes were extracted from articles, and magnitude of between-limb and between-group differences were evaluated using a random-effects model meta-analysis approach to calculate combined pooled effect sizes (ESs) and 95% CIs. ESs were classified as weak ( d < 0.19), small ( d = 0.20-0.49), moderate ( d = 0.50-0.79), or large ( d > 0.80). RESULTS:: The involved limb of individuals with ACLR displayed lower knee extension strength compared with the contralateral limb (ES, -0.78; lower bound [LB], -0.99; upper bound [UB], -0.58) and healthy controls (ES, -0.76; LB, -0.98; UB, -0.53). The involved limb displayed a lower CAR compared with healthy controls (ES, -0.84; LB, -1.18; UB, -0.50) but not compared with the contralateral limb (ES, -0.15; LB, -0.37; UB, 0.07). The ACLR contralateral limb displayed a lower CAR (ES, -0.73; LB, -1.39; UB, -0.07) compared with healthy control limbs but similar knee extension strength (ES, -0.24; LB, -0.68; UB, -0.19). CONCLUSION:: Individuals with ACLR have bilateral CAR deficits and involved limb strength deficits that persist years after surgery. Deficits in quadriceps function may have meaningful implications for patient-reported and objective outcomes, risk of reinjury, and long-term joint health after ACLR.