ABSTRACT
BACKGROUND: Fibroid embolization is a nonsurgical treatment of symptomatic fibroids and is particularly useful in patients with multiple comorbidities. CASE: A 44-year-old woman with multiple comorbidities underwent uterine artery embolization for uterine fibroids. The postprocedure symptoms were controlled with conservative management along with vaginal myomectomy using outlet forceps. CONCLUSION: Postprocedure symptom control is important, and some patients may need emergency medical management of pain and infection and surgical management of partially expelled fibroids.
Subject(s)
Leiomyoma/therapy , Uterine Neoplasms/therapy , Adult , Embolization, Therapeutic , Female , Humans , Leiomyoma/pathology , Magnetic Resonance Imaging , Postoperative Complications , Surgical Instruments , Uterine Artery , Uterine Neoplasms/pathologyABSTRACT
BACKGROUND: The rarity of breast cancer in pregnancy and conflict between the optimal maternal therapy and fetal risks make its management challenging. Chemotherapy is the standard treatment for advanced cases. Epirubicin as a combination agent has been reported for breast and other cancers in pregnancy but not as a single agent. We report a case of advanced breast cancer treated with epirubicin neoadjuvant chemotherapy in pregnancy. CASE: A 30-year-old primigravida with multifocal, grade 3 invasive ductal carcinoma, stage T2 N1M0, received 4 cycles of primary epirubicin chemotherapy in pregnancy from 23 weeks' gestation. The chemotherapy was well tolerated by the mother and fetus, and a good response was achieved prior to postnatal combination chemotherapy and definitive surgery. CONCLUSION: Epirubicin chemotherapy appears safe and effective in pregnancy.