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1.
J Cancer Res Ther ; 19(Supplement): S116-S120, 2023 Apr.
Article in English | MEDLINE | ID: mdl-37147991

ABSTRACT

Background: Distinguishing benign breast diseases (BBDs) from malignant breast diseases is a worrisome entity and should also have knowledge of the pattern of occurrence of the disorders in their geographical location. This research aimed to study the clinical and histopathological pattern of BBD in Indian patients. Materials and Methods: The study was conducted on 153 specimens from lumpectomy, core needle biopsy, and mastectomy. Data regarding patients' age, sex, presenting complaints, duration of the complaints, and history of menstrual cycles and lactation were collected from the biopsy requisition forms and case papers. The tissue bits were processed and stained with hematoxylin and eosin, and a histopathological examination was performed. Results: Most of the patients in the present study were females (n = 151, 98.7%). The mean age of the patients was 30.45 years. Most of the BBD cases (n = 118, 77.14%) were benign, of which fibroadenoma (101 cases) accounted for 66%. Majority of the lesions were in the upper outer quadrant (39.22%). Of the 153 cases, 94 cases of fibroadenoma, one case of breast abscess, nine cases of fibrocystic change, four cases of phyllodes, three cases of lipoma, and one case of gynecomastia diagnosed clinically correlated well with histopathology (n = 112, 73%). Conclusion: BBDs are mostly seen in female patients in the age group of 21-30 years. Fibroadenoma is the most common BBD. Clinical assessment followed by histopathological examination provided an accurate diagnosis. The clinical diagnosis correlated well with histopathology.


Subject(s)
Breast Diseases , Breast Neoplasms , Fibroadenoma , Fibrocystic Breast Disease , Male , Humans , Female , Young Adult , Adult , Breast Neoplasms/diagnosis , Breast Neoplasms/surgery , Breast Neoplasms/epidemiology , Fibroadenoma/diagnosis , Fibroadenoma/surgery , Tertiary Care Centers , Mastectomy , Breast Diseases/diagnosis , Breast Diseases/surgery , Fibrocystic Breast Disease/diagnosis , Fibrocystic Breast Disease/surgery , Fibrocystic Breast Disease/epidemiology
2.
Indian J Pathol Microbiol ; 62(4): 599-601, 2019.
Article in English | MEDLINE | ID: mdl-31611449

ABSTRACT

The estimated incidence of primary cardiac tumors is extremely rare. Among it, cardiac myxoma represents the most common benign cardiac tumor constituting about 80% of cases. We are presenting a 30-year-old female with large left atrial myxoma. She was presented with severe dyspnea, palpitations, and systolic murmurs. On 2D echocardiography, left atrial mass obstructing mitral flow was noted. On cardiac magnetic resonance imaging, a single, large, mobile pedunculated mass lesion in left atrium attached to inferior interatrial septum with heterogeneous enhancement was noted, which was likely represented to be myxoma. The mass was surgically excised and valve repairing was done. We received large, solid, lobulated, gray white, soft-to-firm mass measuring 4.5 × 4.1 × 2.5 cm, and on microscopy showed cardiac myxoma with cartilaginous differentiation. We are presenting this case for its clinical, imaging, and uncommon histological features.


Subject(s)
Heart Neoplasms/diagnostic imaging , Myxoma/diagnostic imaging , Myxoma/pathology , Adult , Arrhythmias, Cardiac/etiology , Echocardiography , Female , Heart Atria/pathology , Heart Neoplasms/pathology , Humans , Magnetic Resonance Imaging
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