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1.
Clin Cardiol ; 47(2): e24182, 2024 Feb.
Article in English | MEDLINE | ID: mdl-38032698

ABSTRACT

BACKGROUND: About 80% of cardiovascular diseases (including heart failure [HF]) occur in low-income and developing countries. However, most clinical trials are conducted in developed countries. HYPOTHESIS: The American Registry of Ambulatory or Acutely Decompensated Heart Failure (AMERICCAASS) aims to describe the sociodemographic characteristics of HF, comorbidities, clinical presentation, and pharmacological management of patients with ambulatory or acutely decompensated HF in America. METHODOLOGY: Descriptive, observational, prospective, and multicenter registry, which includes patients >18 years with HF in an outpatient or hospital setting. Collected information is stored in the REDCap electronic platform. Quantitative variables are defined according to the normality of the variable using the Shapiro-Wilk test. RESULTS: This analysis includes data from the first 1000 patients recruited. 63.5% were men, the median age of 66 years (interquartile range 56.7-75.4), and 77.6% of the patients were older than 55 years old. The percentage of use of the four pharmacological pillars at the time of recruitment was 70.7% for beta-blockers (BB), 77.4% for angiotensin-converting enzyme inhibitor (ACEI)/angiotensin II receptor blocker (ARB II)/angiotensin receptor-neprilysin inhibitor (ARNI), 56.8% for mineralocorticoid receptor antagonists (MRA), and 30.7% for sodium-glucose cotransporter type-2 inhibitors (SGLT2i). The main cause of decompensation in hospitalized patients was HF progression (64.4%), and the predominant hemodynamic profile was wet-warm (68.3%). CONCLUSIONS: AMERICCAASS is the first continental registry to include hospitalized or outpatient patients with HF. Regarding optimal medical therapy, approximately a quarter of the patients still need to receive BB and ACEI/ARB/ARNI, less than half do not receive MRA, and more than two-thirds do not receive SGLT2i.


Subject(s)
Angiotensin-Converting Enzyme Inhibitors , Heart Failure , Male , Humans , United States/epidemiology , Aged , Middle Aged , Female , Angiotensin-Converting Enzyme Inhibitors/therapeutic use , Angiotensin Receptor Antagonists/therapeutic use , Prospective Studies , Stroke Volume , Heart Failure/diagnosis , Heart Failure/drug therapy , Heart Failure/epidemiology , Registries , Adrenergic beta-Antagonists/therapeutic use , Mineralocorticoid Receptor Antagonists/therapeutic use
2.
Arrhythm Electrophysiol Rev ; 12: e03, 2023 Jan.
Article in English | MEDLINE | ID: mdl-36845166

ABSTRACT

Sudden cardiac arrest (SCA) during sports events has a dramatic impact on stadium-goers and the public and is often associated with poor outcomes unless treated with an automated external defibrillator (AED). Despite this, stadiums vary in AED use. This review aims to identify the risks and incidences of SCA, and the use of AEDs in soccer and basketball stadiums. A narrative review of all relevant papers was conducted. Athletes across all sports face an SCA risk of 1:50,000 athlete-years, with the greatest risk of SCA in young male athletes (1:35,000 person-years) and black male athletes (1:18,000 person-years). Africa and South America have the poorest soccer SCA outcomes at 3% and 4% survival. AED use on-site improves survival greater than defibrillation by emergency services. Many stadiums do not have AEDs implemented into medical plans and the AEDs are often unrecognisable or are obstructed. Therefore, AEDs should be used on-site, use clear signalling, have certified trained personnel, and be incorporated into stadiums' medical plans.

3.
Rev. argent. cardiol ; 81(4): 363-366, ago. 2013. ilus, tab
Article in Spanish | LILACS | ID: lil-708644

ABSTRACT

La arteritis de Takayasu se caracteriza por una inflamación granulomatosa que afecta principalmente la aorta y sus ramas. La presentación clínica puede ser variada, dependiendo de la afección arterial. El diagnóstico se sustenta en seis criterios clínicos, determinados por el American College of Rheumatology, y lo confirman la presencia de tres o más de esos criterios. Los casos de arteritis de Takayasu que debutan con un infarto agudo de miocardio son raros. En esta presentación se describe el caso de una paciente de 30 años que ingresó a nuestro hospital con diagnóstico de infarto agudo de miocardio de cara anterior, que requirió angioplastia primaria en la arteria descendente anterior.


Unusual Presentation of Takayasu Arteritis with Myocardial Infarction Takayasu arteritis is characterized by granulomatous inflammation that predominantly affects the aorta and its branches. The clinical presentation may be varied, depending on the affected artery. The diagnosis is based on six clinical criteria established by the American College of Rheumatology, and is confirmed by the presence of three or more of these criteria. The cases of Takayasu arteritis presenting with acute myocardial infarction are rare. This presentation describes the case of a 30 year old patient who was admitted to our hospital with diagnosis of acute anterior wall myocardial infarction, which required primary angioplasty in the anterior descending artery.

4.
Rev. argent. cardiol ; 81(4): 363-366, ago. 2013. ilus, tab
Article in Spanish | BINACIS | ID: bin-130256

ABSTRACT

La arteritis de Takayasu se caracteriza por una inflamación granulomatosa que afecta principalmente la aorta y sus ramas. La presentación clínica puede ser variada, dependiendo de la afección arterial. El diagnóstico se sustenta en seis criterios clínicos, determinados por el American College of Rheumatology, y lo confirman la presencia de tres o más de esos criterios. Los casos de arteritis de Takayasu que debutan con un infarto agudo de miocardio son raros. En esta presentación se describe el caso de una paciente de 30 años que ingresó a nuestro hospital con diagnóstico de infarto agudo de miocardio de cara anterior, que requirió angioplastia primaria en la arteria descendente anterior.(AU)


Unusual Presentation of Takayasu Arteritis with Myocardial Infarction Takayasu arteritis is characterized by granulomatous inflammation that predominantly affects the aorta and its branches. The clinical presentation may be varied, depending on the affected artery. The diagnosis is based on six clinical criteria established by the American College of Rheumatology, and is confirmed by the presence of three or more of these criteria. The cases of Takayasu arteritis presenting with acute myocardial infarction are rare. This presentation describes the case of a 30 year old patient who was admitted to our hospital with diagnosis of acute anterior wall myocardial infarction, which required primary angioplasty in the anterior descending artery.(AU)

5.
Rev Port Cardiol ; 32(7-8): 609-12, 2013.
Article in English, Portuguese | MEDLINE | ID: mdl-23890757

ABSTRACT

Symptoms related to peripheral embolism are experienced in 2%-15% of cases of cardiac myxoma. We present a rare case of a 54-year-old man admitted due to sudden abdominal pain. A computed tomography (CT) scan showed occlusion of the superior mesenteric artery (SMA). As the patient's response to support treatment was favorable, a non-invasive approach was adopted, with prescription of oral anticoagulation (OAC) therapy. Transesophageal echocardiography revealed a tumor in the left atrium. The cardiac mass was completely removed and diagnosed as myxoma by histopathological analysis. As periodic CT scans showed progressive improvement of blood flow through the SMA, OAC was continued. OAC may have been beneficial due to the nature of emboli originating from a cardiac myxoma: thrombi covering the surface of the tumor. At present, there is no explanation in the literature for the benefits of OAC in patients with embolism associated with cardiac myxoma.


Subject(s)
Embolism/etiology , Heart Neoplasms/complications , Ischemia/etiology , Myxoma/complications , Vascular Diseases/etiology , Humans , Male , Mesenteric Ischemia , Middle Aged
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