ABSTRACT
Los tumores carcinoides bronquiales son una causa infrecuente de neumonías de repetición en pacientes jóvenes. El diagnóstico se obtiene mediante pruebas de imagen, broncoscopia y confirmación histológica, y el tratamiento es fundamentalmente quirúrgico. Mediante la presentación de 2 casos, revisamos la utilidad de la gammagrafía con 111In-DTPA-Phe-octreotide (111In-pentetreotida) en la valoración de estos pacientes antes de la cirugía, apoyando el diagnóstico de tumor neuroendocrino ante una imagen sospechosa en otras pruebas (radiografía simple, TC) y descartando enfermedad regional o a distancia. Frente al reducido valor de la PET con 18F-FDG (realizada en uno de los casos), se destaca el papel de laSPECT-TC, que mejora notablemente la localización y la caracterización de los hallazgos
Bronchial carcinoid tumours are an uncommon cause of recurrent pneumonia in young patients. Diagnosis is determined from imaging studies, bronchoscopy, and histological confirmation, and treatment is generally surgical. Two cases are reviewed in order to examine the value of 111In-DTPA-Phe-octreotide (111In-pentetreotide) scintigraphy in the pre-surgical evaluation of these patients. After a suspicious area was observed in other tests (standard X-ray, CT), a neuroendocrine tumour was diagnosed using this technique and the presence of regional or distant disease was ruled out. Comparison with the less valuable 18F-FDG PET (carried out in one of the cases) highlights the usefulness of SPECT-CT, which performs notably better in terms of the localization and characterisation of findings
Subject(s)
Humans , Male , Female , Young Adult , Adolescent , Carcinoid Tumor/complications , Bronchial Neoplasms/complications , Pneumonia/diagnostic imaging , Radionuclide Imaging , Pneumonia/etiology , Indium Radioisotopes , Somatostatin/analogs & derivatives , Diagnostic Imaging , RecurrenceABSTRACT
Bronchial carcinoid tumours are an uncommon cause of recurrent pneumonia in young patients. Diagnosis is determined from imaging studies, bronchoscopy, and histological confirmation, and treatment is generally surgical. Two cases are reviewed in order to examine the value of (111)In-DTPA-Phe-octreotide ((111)In-pentetreotide) scintigraphy in the pre-surgical evaluation of these patients. After a suspicious area was observed in other tests (standard X-ray, CT), a neuroendocrine tumour was diagnosed using this technique and the presence of regional or distant disease was ruled out. Comparison with the less valuable (18)F-FDG PET (carried out in one of the cases) highlights the usefulness of SPECT-CT, which performs notably better in terms of the localization and characterisation of findings.