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1.
An Bras Dermatol ; 94(5): 586-589, 2019.
Article in English | MEDLINE | ID: mdl-31777361

ABSTRACT

Cutaneous neoplasms frequently occur in leprosy, but there are few reports of the coexistence of leprosy and basal cell carcinoma in the same lesion. This case reports a 49-year-old male with an ulcerated plaque on the right lateral nasal wall, bright papules on the sternal region, and a blackened plaque on the right temporal region. The nasal and temporal lesions were diagnosed by histopathology as basal cell carcinoma and melanoma, respectively. The sternal lesions were excised with the repair of the "dog ear" which histopathological examination showed macrophages in the dermis parasitized with acid-fast bacilli, confirming the diagnosis of lepromatous leprosy with Fite-Faraco staining. This case report highlights the importance of referring the dog-ear specimen for histopathologic analysis.


Subject(s)
Carcinoma, Basal Cell/complications , Leprosy, Lepromatous/complications , Melanoma/complications , Skin Neoplasms/complications , Biopsy , Carcinoma, Basal Cell/pathology , Humans , Leprosy, Lepromatous/pathology , Male , Melanoma/pathology , Middle Aged , Skin Neoplasms/pathology
2.
An. bras. dermatol ; An. bras. dermatol;94(5): 586-589, Sept.-Oct. 2019. graf
Article in English | LILACS | ID: biblio-1054853

ABSTRACT

Abstract Cutaneous neoplasms frequently occur in leprosy, but there are few reports of the coexistence of leprosy and basal cell carcinoma in the same lesion. This case reports a 49-year-old male with an ulcerated plaque on the right lateral nasal wall, bright papules on the sternal region, and a blackened plaque on the right temporal region. The nasal and temporal lesions were diagnosed by histopathology as basal cell carcinoma and melanoma, respectively. The sternal lesions were excised with the repair of the "dog ear" which histopathological examination showed macrophages in the dermis parasitized with acid-fast bacilli, confirming the diagnosis of lepromatous leprosy with Fite-Faraco staining. This case report highlights the importance of referring the dog-ear specimen for histopathologic analysis.


Subject(s)
Humans , Male , Middle Aged , Skin Neoplasms/complications , Carcinoma, Basal Cell/complications , Leprosy, Lepromatous/complications , Melanoma/complications , Skin Neoplasms/pathology , Biopsy , Carcinoma, Basal Cell/pathology , Leprosy, Lepromatous/pathology , Melanoma/pathology
3.
Surg. cosmet. dermatol. (Impr.) ; 10(4): 289-297, Out.-Dez. 2018. tab.
Article in English, Portuguese | LILACS | ID: biblio-1007670

ABSTRACT

Microagulhamento ou indução percutânea de colágeno é procedimento dermatológico minimamente invasivo que usa agulhas para criar orifícios ou microcanais na pele. Tem como objetivo induzir formação de colágeno, neovascularização e produção de fatores de crescimento. Há aumento da procura por ser procedimento relativamente simples, com bom custo/benefício, seguro e com resultados satisfatórios. Trata áreas localizadas, e estudos estão se desenvolvendo para avaliar seu potencial em inflamações, discromias e fotodano. O uso terapêutico inclui tratamento de cicatrizes de acne, estrias, rítides, melasma, hiperidrose, alopecia. Atualmente tem sido usado para distribuição transepidérmica de ativos e vacinas.


Microagulhamento ou indução percutânea de colágeno é procedimento dermatológico minimamente invasivo que usa agulhas para criar orifícios ou microcanais na pele. Tem como objetivo induzir formação de colágeno, neovascularização e produção de fatores de crescimento. Há aumento da procura por ser procedimento relativamente simples, com bom custo/benefício, seguro e com resultados satisfatórios. Trata áreas localizadas, e estudos estão se desenvolvendo para avaliar seu potencial em inflamações, discromias e fotodano. O uso terapêutico inclui tratamento de cicatrizes de acne, estrias, rítides, melasma, hiperidrose, alopecia. Atualmente tem sido usado para distribuição transepidérmica de ativos e vacinas.


Subject(s)
Therapeutics , Products Distribution , Dry Needling
4.
An Bras Dermatol ; 93(4): 566-569, 2018.
Article in English | MEDLINE | ID: mdl-30066766

ABSTRACT

Amicrobial pustulosis of the folds is a chronic relapsing neutrophilic dermatosis characterized by sterile pustules compromising skin folds, scalp, face and periorificial regions. It predominantly affects women. Demodicosis is an inflammatory disease associated with cutaneous overpopulation of the mite Demodex spp., the pathogenesis of which is not completely established, but is frequently related to local immunodeficiency. A case of a young woman with amicrobial pustulosis of the folds, and isolated worsening of facial lesions, is reported; investigation revealed overlapping demodicosis. There was complete regression of lesions with acaricide and cyclin treatment. This case warns of a poorly diagnosed but disfiguring and stigmatizing disease, often associated with underlying dermatoses or inadvertent treatments on the face.


Subject(s)
Folliculitis/parasitology , Granuloma/parasitology , Mite Infestations/complications , Mites/classification , Adult , Animals , Doxycycline/therapeutic use , Female , Folliculitis/diagnosis , Folliculitis/drug therapy , Granuloma/diagnosis , Granuloma/drug therapy , Humans , Ivermectin/therapeutic use , Mite Infestations/diagnosis , Mite Infestations/drug therapy
5.
An. bras. dermatol ; An. bras. dermatol;93(4): 566-569, July-Aug. 2018. tab, graf
Article in English | LILACS | ID: biblio-949913

ABSTRACT

Abstract: Amicrobial pustulosis of the folds is a chronic relapsing neutrophilic dermatosis characterized by sterile pustules compromising skin folds, scalp, face and periorificial regions. It predominantly affects women. Demodicosis is an inflammatory disease associated with cutaneous overpopulation of the mite Demodex spp., the pathogenesis of which is not completely established, but is frequently related to local immunodeficiency. A case of a young woman with amicrobial pustulosis of the folds, and isolated worsening of facial lesions, is reported; investigation revealed overlapping demodicosis. There was complete regression of lesions with acaricide and cyclin treatment. This case warns of a poorly diagnosed but disfiguring and stigmatizing disease, often associated with underlying dermatoses or inadvertent treatments on the face.


Subject(s)
Humans , Animals , Female , Adult , Folliculitis/parasitology , Granuloma/parasitology , Mite Infestations/complications , Mites/classification , Ivermectin/therapeutic use , Doxycycline/therapeutic use , Folliculitis/diagnosis , Folliculitis/drug therapy , Granuloma/diagnosis , Granuloma/drug therapy , Mite Infestations/diagnosis , Mite Infestations/drug therapy
6.
Diagn. tratamento ; 22(3): 107-110, Jul.-Aug. 2017.
Article in Portuguese | LILACS | ID: biblio-847992

ABSTRACT

Contexto: Granuloma facial é dermatose rara, benigna, localizada e crônica, com características histopatológicas de vasculite leucocitoclástica. Seu diagnóstico muitas vezes é um desafio para o dermatologista, pois a morfologia da lesão pode simular outras doenças dermatológicas, como carcinoma basocelular. Descrição do caso: Mulher, de 45 anos, fototipo 1 com lesão nasal assintomática há um ano, apresentou-se para exame clínico e dermatoscópico. A lesão assemelhava-se ao carcinoma basocelular, porém o exame histopatológico confirmou tratar-se de granuloma facial. Discussão: As lesões de granuloma facial localizam-se principalmente na face e fazem diferencial com eritema elevatum diutinum,carcinoma basocelular, linfoma cutâneo, pseudolinfoma, entre outros. O exame anatomopatológico é característico, com a presença de infiltrado inflamatório misto predominantemente perivascular. Conclusões: O diagnóstico de granuloma facial deve ser sempre lembrado diante de lesões faciais que se apresentam como placas eritêmato-acastanhadas, sendo necessário, além de exame clínico e dermatoscópico, a avaliação histopatológica.


Subject(s)
Humans , Female , Middle Aged , Carcinoma, Basal Cell , Granuloma , Histology , Vasculitis , Vasculitis, Leukocytoclastic, Cutaneous
7.
An Bras Dermatol ; 92(1): 131-133, 2017.
Article in English | MEDLINE | ID: mdl-28225974

ABSTRACT

Hand-foot syndrome is a common cutaneous adverse effect associated with certain systemic chemotherapy drugs. It is characterized by erythema, edema, and burning sensation, especially over palmoplantar surfaces. We report the case of an elderly patient undergoing chemotherapy after a breast cancer surgery who developed symptoms two months after the start of the regimen. There are no studies that explore specific therapies. Suggestive therapy include reducing agent dosage, increasing the interval between cycles, or even stopping chemotherapy. Emollients, analgesics, and cold packs are described as effective. After alopecia and mucositis, hand-foot syndrome is the most common adverse dermatologic reaction to chemotherapeutic agents.


Subject(s)
Antineoplastic Agents/adverse effects , Hand-Foot Syndrome/etiology , Aged , Antineoplastic Agents/therapeutic use , Breast Neoplasms/drug therapy , Female , Hand-Foot Syndrome/diagnosis , Hand-Foot Syndrome/pathology , Humans
8.
An. bras. dermatol ; An. bras. dermatol;92(1): 131-133, Jan.-Feb. 2017. tab, graf
Article in English | LILACS | ID: biblio-838019

ABSTRACT

ABSTRACT Hand-foot syndrome is a common cutaneous adverse effect associated with certain systemic chemotherapy drugs. It is characterized by erythema, edema, and burning sensation, especially over palmoplantar surfaces. We report the case of an elderly patient undergoing chemotherapy after a breast cancer surgery who developed symptoms two months after the start of the regimen. There are no studies that explore specific therapies. Suggestive therapy include reducing agent dosage, increasing the interval between cycles, or even stopping chemotherapy. Emollients, analgesics, and cold packs are described as effective. After alopecia and mucositis, hand-foot syndrome is the most common adverse dermatologic reaction to chemotherapeutic agents.


Subject(s)
Humans , Female , Aged , Hand-Foot Syndrome/etiology , Antineoplastic Agents/adverse effects , Breast Neoplasms/drug therapy , Hand-Foot Syndrome/diagnosis , Hand-Foot Syndrome/pathology , Antineoplastic Agents/therapeutic use
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