ABSTRACT
Insect bite hypersensitivity (IBH) is an IgE-mediated dermatitis of horses caused by bites of Culicoides spp. IBH does not occur in Iceland where Culicoides are absent. However, following importation into continental Europe where Culicoides are present, >or=50% of Icelandic horses (1st generation) develop IBH but Subject(s)
Ceratopogonidae/immunology
, Horse Diseases/immunology
, Horse Diseases/parasitology
, Insect Bites and Stings/veterinary
, Interleukin-4/immunology
, Th2 Cells/immunology
, Animals
, Feces/parasitology
, Flow Cytometry/veterinary
, Helminthiasis, Animal/blood
, Helminthiasis, Animal/immunology
, Helminthiasis, Animal/parasitology
, Helminths/immunology
, Horses
, Iceland
, Immunoglobulin E/blood
, Immunoglobulin G/blood
, Insect Bites and Stings/immunology
, Insect Bites and Stings/parasitology
, Interleukin-4/biosynthesis
, Interleukin-4/blood
, Leukocytes, Mononuclear/immunology
, Parasite Egg Count/veterinary