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1.
J Aging Health ; 35(9): 677-687, 2023 10.
Article in English | MEDLINE | ID: mdl-35658697

ABSTRACT

OBJECTIVE: The objective is to determine associations between stressors and pain across the late-life span. METHOD: Multilevel linear modeling was applied separately to harmonized repeated measures data from the Longitudinal Late-Life Health study (LLLH; n = 342; 13-year interval) and the Health and Retirement Study (HRS; n = 2959; 8-year interval). RESULTS: In both the LLLH and HRS samples, independent of age, gender, and race, participants with higher average stressor levels experienced more numerous painful conditions and higher pain severity over the study intervals. In the HRS sample, they also experienced higher levels of pain interference. In general, participants' stressor levels did not influence rates of increase in their pain. Gender and race had few moderating effects on associations between stressors and pain. DISCUSSION: Stressors and pain are associated across the late-life span. Future research should focus on the mediating mechanisms that account for this association and the moderating factors that affect its strength.


Subject(s)
Longevity , Stress, Psychological , Humans , Aging , Longitudinal Studies , Pain
2.
BMC Public Health ; 21(1): 2319, 2021 12 23.
Article in English | MEDLINE | ID: mdl-34949174

ABSTRACT

OBJECTIVE: To examine the moderating effect of older adults' history of drinking problems on the relationship between their baseline alcohol consumption and risk of dementia and cognitive impairment, no dementia (CIND) 18 years later. METHOD: A longitudinal Health and Retirement Study cohort (n = 4421) was analyzed to demonstrate how older adults' baseline membership in one of six drinking categories (non-drinker, within-guideline drinker, and outside-guideline drinker groups, divided to reflect absence or presence of a history of drinking problems) predicts dementia and CIND 18 years later. RESULTS: Among participants with no history of drinking problems, 13% of non-drinkers, 5% of within-guideline drinkers, and 9% of outside-guideline drinkers were classified as having dementia 18-years later. Among those with a history of drinking problems, 14% of non-drinkers, 9% of within-guideline drinkers, and 7% of outside-guideline drinkers were classified with dementia. With Non-Drinker, No HDP as reference category, being a baseline within-guideline drinker with no history of drinking problems reduced the likelihood of dementia 18 years later by 45%, independent of baseline demographic and health characteristics; being a baseline within-guideline drinker with a history of drinking problems reduced the likelihood by only 13% (n.s.). Similar patterns obtained for the prediction of CIND. CONCLUSIONS: For older adults, consuming alcohol at levels within validated guidelines for low-risk drinking may offer moderate long-term protection from dementia and CIND, but this effect is diminished by having a history of drinking problems. Efforts to predict and prevent dementia and CIND should focus on older adults' history of drinking problems in addition to how much alcohol they consume.


Subject(s)
Alcoholism , Cognitive Dysfunction , Dementia , Aged , Alcohol Drinking/epidemiology , Alcohol Drinking/prevention & control , Alcohol Drinking/psychology , Alcoholism/epidemiology , Alcoholism/prevention & control , Alcoholism/psychology , Cohort Studies , Dementia/epidemiology , Dementia/prevention & control , Humans
3.
Pain Med ; 21(10): 2123-2136, 2020 10 01.
Article in English | MEDLINE | ID: mdl-32955090

ABSTRACT

OBJECTIVE: To examine stressor elevations among older adults with pain, and gender and race disparities in the dual burdens of late-life pain and stressors. DESIGN: Cross-sectional. SETTING: Community. SUBJECTS: Participants in the Longitudinal Late-Life Health study (LLLH; N = 1,884) and the Health and Retirement Study (HRS; N = 7,704). METHODS: Pain and stressor measures were harmonized across the LLLH and HRS samples. Analyses of covariance were conducted to determine the effects of older adults' pain, gender, race, and interactions between these factors, on their stressors in nine separate life domains, and in stressors overall. RESULTS: In both the LLLH and HRS samples, older adults with painful conditions (joint, back, headache, chest pain), more numerous painful conditions, more severe pain, and more pain interference had elevated stressors in all life domains, compared with older adults without or with less serious pain. Pain was more prevalent among women and nonwhites than men and whites. Stressor exposure was higher for men than women in most life domains; it was higher for nonwhites than whites in all life domains. For certain types of pain and life domains, pain and gender, as well as pain and race, interacted to predict stressor elevations. CONCLUSIONS: Late-life pain is associated with elevations in stressors, and there are gender and race disparities in the dual burdens of heightened pain and elevated stressors in later life. Pain and stressors are not consistently more strongly linked among older women than older men, or among older nonwhite than older white persons.


Subject(s)
Pain , White People , Aged , Cross-Sectional Studies , Female , Headache , Humans , Longitudinal Studies , Male , Pain/epidemiology
4.
Pain Med ; 21(3): 488-500, 2020 03 01.
Article in English | MEDLINE | ID: mdl-31407787

ABSTRACT

OBJECTIVE: To determine the key classes of nursing home residents' nine-month pain trajectories, the influence of residents' mental health disorders on membership in these classes, and nine-month health-related outcomes associated with pain trajectory class membership. METHODS: Four times over a nine-month period, the MDS 3.0 resident assessment instrument was used to record the demographic characteristics, mental health disorder diagnoses, pain characteristics, and health and functioning outcomes of 2,539 Department of Veterans Affairs Community Living Center (VA CLC) residents. Growth mixture modeling was used to estimate the key classes of residents' nine-month pain trajectories, the influence of residents' mental health disorders on their pain trajectory class membership, and the associations of class membership with residents' health and functioning outcomes at nine-month follow-up. RESULTS: Four-class solutions best described nursing home residents' nine-month trajectories of pain frequency, severity, and interference. Residents with dementia and severe mental illness diagnoses were less likely, and those with depressive disorder, PTSD, and substance use disorder diagnoses more likely, to belong to adverse nine-month pain trajectory classes. Membership in adverse pain frequency and pain severity trajectory classes, and in trajectory classes characterized by initially high but steeply declining pain interference, portended more depressive symptoms but better cognitive and physical functioning at nine-month follow-up. CONCLUSIONS: Nursing home residents' mental health disorder diagnoses help predict their subsequent pain frequency, severity, and interference trajectories. This may be clinically useful information for improving pain assessment and treatment approaches for nursing home residents.


Subject(s)
Mental Disorders/complications , Pain/epidemiology , Pain/psychology , Aged , Aged, 80 and over , Female , Homes for the Aged , Humans , Male , Middle Aged , Nursing Homes
5.
Aging Ment Health ; 23(9): 1146-1155, 2019 09.
Article in English | MEDLINE | ID: mdl-30404536

ABSTRACT

Objective: This study evaluated: (a) associations between long-term care residents' mental health disorder diagnoses and their pain self-reports and pain treatments, and (b) the extent to which communication, cognitive, and physical functioning problems help explain disparities in the pain and pain treatments of long-term care residents with and without mental health disorders. Method: Minimum Data Set 3.0 records of 8,300 residents of Department of Veterans Affairs Community Living Centers were used to determine statistically unadjusted and adjusted cross-sectional associations between residents' mental health diagnoses and their pain and pain treatments. Results: Residents diagnosed with dementia and serious mental illness (SMI) were less likely, and those diagnosed with depressive disorder, post-traumatic stress disorder (PTSD), and substance use disorder (SUD) were more likely, to report recent, severe, and debilitating pain. Among residents affirming recent pain, those with dementia or SMI diagnoses were twice as likely to obtain no treatment for their pain and significantly less likely to receive as-needed pain medication and non-pharmacological pain treatments than were other residents. Those with either depressive disorder or PTSD were more likely, and those with SUD less likely, to obtain scheduled pain medication. In general, these associations remained even after statistically adjusting for residents' demographic characteristics, other mental health disorder diagnoses, and functioning. Conclusion: Long-term care residents with mental health disorders experience disparities in pain and pain treatment that are not well-explained by their functioning deficits. They may benefit from more frequent, thorough pain assessments and from more varied and closely tailored pain treatment approaches.


Subject(s)
Mental Disorders/classification , Pain Management/methods , Pain/epidemiology , Veterans/psychology , Aged , Cross-Sectional Studies , Dementia/epidemiology , Female , Humans , Long-Term Care/statistics & numerical data , Male , Mental Disorders/epidemiology , Middle Aged , Self Report
6.
Alcohol Clin Exp Res ; 42(4): 795-802, 2018 Apr.
Article in English | MEDLINE | ID: mdl-29417610

ABSTRACT

BACKGROUND: There is a lack of research on the role of alcohol consumption in cigarette smoking among older adults, and the few studies on alcohol use and smoking with older adults have failed to distinguish between average level and pattern of drinking as predictors of smoking. The main purpose of this study was to examine the independent contributions of average level versus pattern of drinking as predictors of cigarette smoking among older adults. A subsidiary purpose was to examine the link between continued smoking and mortality among older smokers. METHODS: We investigated average level and pattern of drinking as predictors of current smoking among 1,151 older adults at baseline and of continued smoking and mortality among the subset of 276 baseline smokers tracked across 20 years. We used multiple linear and logistic regression analyses and, to test mediation, bias-corrected bootstrap confidence intervals. RESULTS: A high level of average drinking and a pattern of episodic heavy drinking were concurrently associated with smoking at baseline. However, only episodic heavy drinking was prospectively linked to continued smoking among baseline smokers. Continued smoking among baseline smokers increased the odds of 20-year mortality and provided an indirect pathway through which heavy episodic drinking related to mortality. CONCLUSIONS: Smokers who misuse alcohol are a challenging population for smoking cessation efforts. Older adults who concurrently misuse alcohol and smoke cigarettes provide a unique target for public health interventions.


Subject(s)
Alcohol Drinking/epidemiology , Cigarette Smoking/epidemiology , Aged , Cigarette Smoking/mortality , Comorbidity , Female , Humans , Male , Middle Aged , United States/epidemiology
7.
Psychol Serv ; 14(3): 327-336, 2017 Aug.
Article in English | MEDLINE | ID: mdl-28805417

ABSTRACT

In 2011, the Veterans Health Administration (VHA) began implementing consistent staff assignment in its nursing homes (called Community Living Centers or CLCs). Consistent assignment, a cornerstone of culture change, minimizes the number of staff who provide a resident's care. The present research assessed the level and stability of consistent assignment in units within VHA CLCs and identified unit characteristics related to implementation of this staff assignment model. Schedulers in 185 of 335 organizational units that make up VHA CLCs completed a Staffing Practices Survey. For the month prior to the survey, 53% of CLC units had full implementation of consistent assignment. Tracked back over time, 37% of CLC units had stable high consistent assignment, 29% had stable low consistent assignment, and 34% were variable. Units with stable high consistent assignment were most likely to use care teams with stable membership and to obtain staff input for care assignments. Schedulers in these units reported more positive experiences with consistent staff assignment and better unit functioning in terms of staff absences, complaints about workload fairness, and resolution of scheduling problems. Units with stable low and variable consistent assignment were similar in most of these respects; however, units with variable consistent assignment made greater use of stable care teams and were less likely to change assignments at a staff member's request. Overall, consistent assignment implementation was not related to unit size, nursing hours per resident day, or specialty focus. Findings can help guide consistent staff assignment implementation in VHA and community nursing homes. (PsycINFO Database Record


Subject(s)
Nursing Homes/organization & administration , Organizational Culture , Organizational Innovation , Quality Improvement/organization & administration , Workload , Humans , Quality of Health Care , United States , United States Department of Veterans Affairs , Veterans Health
8.
J Stud Alcohol Drugs ; 78(3): 435-441, 2017 05.
Article in English | MEDLINE | ID: mdl-28499111

ABSTRACT

OBJECTIVE: Research on late-middle-aged and older adults has focused primarily on average level of alcohol consumption, overlooking variability in underlying drinking patterns. The purpose of the present study was to examine the independent contributions of an episodic heavy pattern of drinking versus a high average level of drinking as prospective predictors of drinking problems. METHOD: The sample comprised 1,107 adults ages 55-65 years at baseline. Alcohol consumption was assessed at baseline, and drinking problems were indexed across 20 years. We used prospective negative binomial regression analyses controlling for baseline drinking problems, as well as for demographic and health factors, to predict the number of drinking problems at each of four follow-up waves (1, 4, 10, and 20 years). RESULTS: Across waves where the effects were significant, a high average level of drinking (coefficients of 1.56, 95% CI [1.24, 1.95]; 1.48, 95% CI [1.11, 1.98]; and 1.85, 95% CI [1.23, 2.79] at 1, 10, and 20 years) and an episodic heavy pattern of drinking (coefficients of 1.61, 95% CI [1.30, 1.99]; 1.61, 95% CI [1.28, 2.03]; and 1.43, 95% CI [1.08, 1.90] at 1, 4, and 10 years) each independently increased the number of drinking problems by more than 50%. CONCLUSIONS: Information based only on average consumption underestimates the risk of drinking problems among older adults. Both a high average level of drinking and an episodic heavy pattern of drinking pose prospective risks of later drinking problems among older adults.


Subject(s)
Alcohol Drinking/epidemiology , Alcoholism/epidemiology , Age Factors , Aged , Female , Humans , Longitudinal Studies , Male , Middle Aged , Prospective Studies , Risk
9.
Womens Health Issues ; 27(4): 463-470, 2017.
Article in English | MEDLINE | ID: mdl-28325585

ABSTRACT

BACKGROUND: Studies suggest that women may be at greater risk for developing chronic pain and pain-related disability. METHODS: Because musculoskeletal disorders (MSD) are the most frequently endorsed painful conditions among veterans, we sought to characterize gender differences in sociodemographic and clinical correlates among veterans upon entry into Veterans Health Administration's Musculoskeletal Disorders Cohort (n = 4,128,008). RESULTS: Women were more likely to be younger, Black, unmarried, and veterans of recent conflicts. In analyses adjusted for gender differences in sociodemographics, women were more likely to have diagnoses of fibromyalgia, temporomandibular disorders, and neck pain. Almost one in five women (19.4%) had more than one MSD diagnosis, compared with 15.7% of men; this higher risk of MSD multimorbidity remained in adjusted analyses. Adjusting for sociodemographics, women with MSD were more likely to have migraine headache and depressive, anxiety, and bipolar disorders. Women had lower odds of cardiovascular diseases, substance use disorders, and several MSDs, including back pain conditions. Men were more likely to report "no pain" on the pain intensity Numeric Rating Scale, whereas more women (41%) than men (34%) reported moderate to severe pain (Numeric Rating Scale 4+). CONCLUSIONS: Because women veterans are more likely to have conditions such as fibromyalgia and mental health conditions, along with greater pain intensity in the setting of MSD, women-specific pain services may be needed.


Subject(s)
Musculoskeletal Diseases/diagnosis , Musculoskeletal Pain/diagnosis , Veterans/psychology , Adult , Aged , Anxiety/epidemiology , Chronic Pain , Cohort Studies , Female , Humans , Male , Middle Aged , Migraine Disorders/epidemiology , Musculoskeletal Diseases/classification , Musculoskeletal Diseases/epidemiology , Musculoskeletal Pain/epidemiology , Pain Management , Severity of Illness Index , Sex Factors , Socioeconomic Factors , Substance-Related Disorders/epidemiology , United States/epidemiology , United States Department of Veterans Affairs , Veterans/statistics & numerical data
10.
Transl Behav Med ; 6(4): 605-612, 2016 12.
Article in English | MEDLINE | ID: mdl-27384953

ABSTRACT

This study provides an example of how healthcare system-wide progress in implementation of opioid-therapy guideline recommendations can be longitudinally assessed and then related to subsequent opioid-prescribed patient health and safety outcomes. Using longitudinal linear mixed effects analyses, we determined that in the Department of Veterans Affairs (VA) healthcare system (n = 141 facilities), over the 4-year interval from 2010 to 2013, a key opioid therapy guideline recommendation, urine drug screening (UDS), increased from 29 to 42 %, with an average within-facility increase rate of 4.5 % per year. Higher levels of UDS implementation from 2010 to 2013 were associated with lower risk of suicide and drug overdose events among VA opioid-prescribed patients in 2013, even after adjusting for patients' 2012 demographic characteristics and medical and mental health comorbidities. Findings suggest that VA clinicians and healthcare policymakers have been responsive to the 2010 VA/Department of Defense (DOD) UDS treatment guideline recommendation, resulting in improved patient safety for VA opioid-prescribed patients.


Subject(s)
Analgesics, Opioid/administration & dosage , Drug Evaluation, Preclinical/methods , Drug Overdose/prevention & control , Practice Guidelines as Topic , Prescription Drug Misuse/adverse effects , Suicide Prevention , Aged , Analgesics, Opioid/poisoning , Analgesics, Opioid/therapeutic use , Analgesics, Opioid/urine , Drug Overdose/complications , Drug Overdose/urine , Female , Guideline Adherence , Humans , Male , Middle Aged , Suicide/statistics & numerical data , United States/epidemiology , United States Department of Veterans Affairs , Veterans/psychology
11.
J Aging Health ; 28(5): 911-32, 2016 08.
Article in English | MEDLINE | ID: mdl-26628481

ABSTRACT

OBJECTIVE: To determine effects of late-middle-aged adults' baseline drinking behavior on their subsequent 10-year depressive symptom trajectories. METHOD: Health and Retirement Study participants (N = 7,939) were assessed on baseline demographic, health, and drinking characteristics, and biennially assessed for the next 10 years on their depressive symptoms. RESULTS: Growth mixture modeling generated four classes of depressive symptom trajectories: Consistently low (72%), consistently elevated (6%), increasing (12%), and decreasing (10%). Baseline abstinence from alcohol, possibly enforced by poorer health and a history of drinking problems, and heavier drinking, "binge" drinking, and having a history of drinking problems, raised risk of membership in the "consistently elevated" class. Abstinence by participants without history of drinking problems-and light, moderate, and heavier drinking-protected against membership in the "increasing" class. Abstinence by participants without history of drinking problems elevated-and moderate drinking reduced-likelihood of membership in the "decreasing" class. DISCUSSION: Late-middle-aged adults' alcohol use is associated with the subsequent long-term course of their depressive symptoms.


Subject(s)
Alcohol Drinking/psychology , Depression/epidemiology , Alcohol Drinking/epidemiology , Female , Health Surveys , Humans , Longitudinal Studies , Male , Middle Aged , United States/epidemiology
12.
J Stud Alcohol Drugs ; 76(4): 552-8, 2015 Jul.
Article in English | MEDLINE | ID: mdl-26098030

ABSTRACT

OBJECTIVE: Research on moderate drinking has focused on the average level of drinking. Recently, however, investigators have begun to consider the role of the pattern of drinking, particularly heavy episodic drinking, in mortality. The present study examined the combined roles of average drinking level (moderate vs. high) and drinking pattern (regular vs. heavy episodic) in 20-year total mortality among late-life drinkers. METHOD: The sample comprised 1,121 adults ages 55-65 years. Alcohol consumption was assessed at baseline, and total mortality was indexed across 20 years. We used multiple logistic regression analyses controlling for a broad set of sociodemographic, behavioral, and health status covariates. RESULTS: Among individuals whose high level of drinking placed them at risk, a heavy episodic drinking pattern did not increase mortality odds compared with a regular drinking pattern. Conversely, among individuals who engage in a moderate level of drinking, prior findings showed that a heavy episodic drinking pattern did increase mortality risk compared with a regular drinking pattern. Correspondingly, a high compared with a moderate drinking level increased mortality risk among individuals maintaining a regular drinking pattern, but not among individuals engaging in a heavy episodic drinking pattern, whose pattern of consumption had already placed them at risk. CONCLUSIONS: Findings highlight that low-risk drinking requires that older adults drink low to moderate average levels of alcohol and avoid heavy episodic drinking. Heavy episodic drinking is frequent among late-middle-aged and older adults and needs to be addressed along with average consumption in understanding the health risks of late-life drinkers.


Subject(s)
Alcohol Drinking/epidemiology , Alcoholism/epidemiology , Health Status , Aged , Alcohol Drinking/mortality , Alcoholism/mortality , Female , Humans , Male , Middle Aged , Risk
13.
Alcohol Clin Exp Res ; 38(5): 1432-8, 2014 May.
Article in English | MEDLINE | ID: mdl-24588326

ABSTRACT

BACKGROUND: Analyses of moderate drinking have focused overwhelmingly on average consumption, which masks diverse underlying drinking patterns. This study examined the association between episodic heavy drinking and total mortality among moderate-drinking older adults. METHODS: At baseline, the sample was comprised of 446 adults aged 55 to 65; 74 moderate drinkers who engaged in episodic heavy drinking and 372 regular moderate drinkers. The database at baseline also included a broad set of sociodemographic, behavioral, and health status covariates. Death across a 20-year follow-up period was confirmed primarily by death certificate. RESULTS: In multiple logistic regression analyses, after adjusting for all covariates, as well as overall alcohol consumption, moderate drinkers who engaged in episodic heavy drinking had more than 2 times higher odds of 20-year mortality in comparison with regular moderate drinkers. CONCLUSIONS: Among older moderate drinkers, those who engage in episodic heavy drinking show significantly increased total mortality risk compared to regular moderate drinkers. Episodic heavy drinking-even when average consumption remains moderate-is a significant public health concern.


Subject(s)
Alcohol Drinking/mortality , Binge Drinking/mortality , Age Factors , Aged , Female , Humans , Logistic Models , Male , Marital Status , Middle Aged , Risk Factors , Sex Factors , Social Support , Socioeconomic Factors
14.
Am J Geriatr Psychiatry ; 22(8): 792-800, 2014 Aug.
Article in English | MEDLINE | ID: mdl-23659899

ABSTRACT

OBJECTIVE: Effective pain assessment and pain treatment are key goals in community nursing homes, but residents' psychiatric disorders may interfere with attaining these goals. This study addressed whether (1) pain assessment and treatment obtained by nursing home residents with psychiatric disorders differs from that obtained by residents without psychiatric disorders; (2) this difference is found consistently across the four types of psychiatric disorder most prevalent in nursing homes (dementia, depression, serious mental illness, and substance use disorder); and (3) male gender, non-white, and longer length of stay add to psychiatric disorders to elevate risk of potentially adverse pain ratings and pain treatments. METHODS: In this cross-sectional study, we examined relationships among National Nursing Home Survey 2004 residents' demographic, diagnostic, pain, and pain treatment characteristics. RESULTS: Compared with residents without psychiatric disorders, those with psychiatric disorders were less likely to be rated as having pain in the last 7 days and had lower and more "missing" or "don't know" pain severity ratings. They also were less likely to obtain opioids and more likely to be given only nonopioid pain medications, even after statistically adjusting for demographic factors, physical functioning, and pain severity. These effects generally held across all four types of psychiatric disorders most prevalent in nursing homes and were compounded by male, non-white, and longer-stay status. CONCLUSION: Psychiatric disorders besides dementia may impact pain assessment and treatment in nursing homes. Nursing home residents with psychiatric disorders, especially male, non-white, and longer-stay residents, should be targeted for improved pain care.


Subject(s)
Mental Disorders/epidemiology , Nursing Homes , Pain Management/statistics & numerical data , Aged, 80 and over , Cross-Sectional Studies , Female , Health Surveys , Humans , Length of Stay/statistics & numerical data , Male , Nursing Homes/statistics & numerical data , Pain Measurement/statistics & numerical data , Prevalence , Racial Groups/statistics & numerical data , Sex Factors , United States/epidemiology
15.
J Aging Health ; 25(4): 656-77, 2013 Jun.
Article in English | MEDLINE | ID: mdl-23640817

ABSTRACT

OBJECTIVE: To determine whether (a) late-life pain predicts growth in older adults' use of alcohol, and elevated risk of drinking problems; and (b) sociodemographic characteristics moderate these relationships. METHOD: Five times over an 8-year interval, N = 5,446 Health and Retirement Study (HRS) participants provided information about their pain and alcohol use. Two-part latent growth modeling and logistic regression were used to analyze these data. RESULTS: Participants with more pain at baseline had lower initial levels and a faster rate of decline over the next 8 years in alcohol consumption, but they also were at elevated risk of having drinking problems. Income and African American background interacted with pain to predict 8-year change in alcohol consumption and presence of drinking problems. DISCUSSION: Late-life pain does not predict growth in older adults' alcohol consumption, but is nonetheless linked to elevated risk of drinking problems, especially among African Americans.


Subject(s)
Alcohol Drinking/epidemiology , Alcohol-Related Disorders/epidemiology , Pain/epidemiology , Black or African American/psychology , Black or African American/statistics & numerical data , Aged , Female , Humans , Male , Middle Aged , Prospective Studies , Risk Factors , Severity of Illness Index , Socioeconomic Factors
16.
J Clin Psychiatry ; 74(12): 1241-8, 2013 Dec.
Article in English | MEDLINE | ID: mdl-24434093

ABSTRACT

OBJECTIVE: Benzodiazepines, other anxiolytics, or sedative hypnotics are prescribed for 30%-50% of posttraumatic stress disorder (PTSD) patients. Prior data and theory suggest that these medications may inhibit response to exposure therapy, one of the most effective PTSD treatments. The present post hoc study reanalyzed results from a psychotherapy trial to assess whether benzodiazepine use was associated with reduced response to exposure therapy. METHOD: Between August 2002 and October 2005, 283 female veterans and soldiers meeting DSM-IV criteria for PTSD were randomly assigned to 10 weekly 90-minute sessions of either prolonged exposure (n = 140) or present-centered psychotherapy (n = 143). Benzodiazepine use (n = 57) or non-use (n = 226) at intake was not randomly assigned. Multilevel modeling was used to assess the effects of benzodiazepine status, psychotherapy condition, and their interaction on changes on the Clinician-Administered PTSD Scale and the PTSD Checklist during the treatment and 6-month follow-up periods. RESULTS: Consistent with prior reports from these data, prolonged exposure psychotherapy produced greater reductions per week in PTSD symptoms than did present-centered psychotherapy (b = -0.48, P = .02). Patients prescribed benzodiazepines did not have weaker response to prolonged exposure, but demonstrated poorer posttreatment maintenance of gains from present-centered psychotherapy (b = -0.78, P < .001). CONCLUSIONS: Prolonged exposure is a sufficiently robust treatment that patients who are taking benzodiazepines can benefit from it. It is unclear whether benzodiazepine use or other patient factors accounted for benzodiazepine recipients' poorer maintenance of gains in present-centered psychotherapy. TRIAL REGISTRATION: ClinicalTrials.gov identifier: NCT00032617.


Subject(s)
Benzodiazepines , Military Personnel/psychology , Psychotherapy/methods , Stress Disorders, Post-Traumatic , Veterans/psychology , Adult , Benzodiazepines/administration & dosage , Benzodiazepines/adverse effects , Combined Modality Therapy , Diagnostic and Statistical Manual of Mental Disorders , Drug Monitoring/methods , Female , Humans , Hypnotics and Sedatives/administration & dosage , Hypnotics and Sedatives/adverse effects , Middle Aged , Military Personnel/statistics & numerical data , Psychiatric Status Rating Scales , Stress Disorders, Post-Traumatic/psychology , Stress Disorders, Post-Traumatic/therapy , Treatment Outcome , United States , Veterans/statistics & numerical data
17.
J Stud Alcohol Drugs ; 73(1): 80-8, 2012 Jan.
Article in English | MEDLINE | ID: mdl-22152665

ABSTRACT

OBJECTIVE: This study examined level of wine consumption and total mortality among 802 older adults ages 55-65 at baseline, controlling for key sociodemographic, behavioral, and health status factors. Despite a growing consensus that moderate alcohol consumption is associated with reduced total mortality, whether wine consumption provides an additional, unique protective effect is unresolved. METHOD: Participants were categorized in three subsamples: abstainers, high-wine-consumption moderate drinkers, and low-wine-consumption moderate drinkers. Alcohol consumption, sociodemographic factors, health behavior, and health problems were assessed at baseline; total mortality was indexed across an ensuing 20-year period. RESULTS: After adjusting for all covariates, both high-wine-consumption and low-wine-consumption moderate drinkers showed reduced mortality risks compared with abstainers. Further, compared with moderate drinkers for whom a high proportion of ethanol came from wine, those for whom a low proportion of ethanol came from wine were older, were more likely to be male, reported more health problems, were more likely to be tobacco smokers, scored lower on socioeconomic status, and (statistical trend) reported engaging in less physical activity. Controlling only for overall ethanol consumption, compared with moderate drinkers for whom a high proportion of ethanol came from wine, those for whom a low proportion of ethanol came from wine showed a substantially increased 20-year mortality risk of 85%. However, after controlling for all covariates, the initial mortality difference associated with wine consumption was no longer significant. CONCLUSIONS: Among older adults who are moderate drinkers, the apparent unique effects of wine on longevity may be explained by confounding factors correlated with wine consumption.


Subject(s)
Alcohol Drinking/mortality , Alcohol Drinking/trends , Wine , Age Factors , Aged , Alcohol Drinking/physiopathology , Female , Follow-Up Studies , Humans , Longevity/physiology , Male , Middle Aged
18.
Pain Med ; 12(7): 1049-59, 2011 Jul.
Article in English | MEDLINE | ID: mdl-21668742

ABSTRACT

OBJECTIVE: To determine associations between older adults' baseline painful medical conditions and their 10-year drinking behavior, and whether personal and life context characteristics moderate these associations. METHODS: At baseline, then, 1, 4, and 10 years later, late-middle-aged community residents (M = 61 years; N = 1,291) were surveyed regarding their painful medical conditions, use of alcohol, and personal and life context characteristics. Latent growth modeling was used to determine concurrent and prospective relationships between painful medical conditions and 10-year drinking behavior, and moderating effects of personal and life context characteristics on these relationships. RESULTS: At baseline, individuals reporting more numerous painful medical conditions consumed alcohol less frequently, but had more frequent drinking problems, than did individuals with fewer such conditions. Being female and having more interpersonal social resources strengthened the association between painful medical conditions and less ethanol consumed. For men more so than women, more numerous painful medical conditions were associated with more frequent drinking problems. Baseline painful medical conditions alone had no prospective effect on 10-year change in drinking behavior, but being older and having more interpersonal social resources made it more likely that baseline painful medical conditions would predict decline over time in frequency of alcohol consumption and drinking problems. CONCLUSIONS: Late-middle-aged individuals who have more numerous painful medical conditions reduce alcohol consumption but nonetheless remain at risk for more frequent drinking problems. Gender, age, and interpersonal social resources moderate the influence of painful medical conditions on late-life alcohol use. These results imply that older individuals with pain are at little immediate or long-term risk for increased alcohol consumption, but clinicians should remain alert to drinking problems among their older pain patients, especially men.


Subject(s)
Alcohol Drinking , Pain/physiopathology , Aged , Alcoholism , Female , Humans , Longitudinal Studies , Male , Middle Aged , Prospective Studies , Stress, Psychological
19.
J Stud Alcohol Drugs ; 72(2): 308-21, 2011 Mar.
Article in English | MEDLINE | ID: mdl-21388604

ABSTRACT

OBJECTIVE: The aim of this study was to describe older adults' 20-year alcohol-consumption and drinking-problem trajectories, identify baseline predictors of them, and determine whether older men and women differ on late-life drinking trajectory characteristics and predictors. METHOD: Two-group simultaneous latent growth modeling was used to describe the characteristics and baseline predictors of older community-residing men's (n = 399) and women's (n = 320) 20-year drinking trajectories. Chi-square difference tests of increment in fit of latent growth models with and without gender invariance constraints were used to determine gender differences in drinking trajectory characteristics and predictors. RESULTS: Unconditional quadratic growth models best described older individuals' within-individual, 20-year drinking trajectories, with alcohol consumption following an average pattern of delayed decline, and drinking problems an average pattern of decline followed by leveling off. On average, older men declined in alcohol consumption somewhat later than did older women. The best baseline predictors of more rapid decline in alcohol consumption and drinking problems were drinking variables indicative of heavier, more problematic alcohol use at late middle age. CONCLUSIONS: The course of alcohol consumption and drinking problems from late middle age onward is one of net decline, but this decline is neither swift nor invariable. Gender differences in the timing of decline in drinking suggest that ongoing monitoring of alcohol consumption may be especially important for older men. Further research is needed to identify factors known at late middle age that prospectively explain long-term change in late-life use of alcohol.


Subject(s)
Alcohol Drinking/psychology , Alcohol Drinking/trends , Alcoholism/psychology , Aged , Alcoholism/metabolism , Female , Forecasting , Health Surveys , Humans , Longitudinal Studies , Male , Middle Aged , Models, Theoretical , Psychiatric Status Rating Scales , Risk Factors , Risk-Taking , Sex Factors , Social Environment , Time Factors
20.
Addiction ; 106(2): 324-34, 2011 Feb.
Article in English | MEDLINE | ID: mdl-20883458

ABSTRACT

AIMS: This study compares the personal, family and social functioning of older husbands and wives concordant or discordant for high-risk alcohol consumption and identifies predictors of changes in concordance and high-risk consumption. DESIGN, PARTICIPANTS, MEASUREMENTS: Three groups of couples were identified at baseline and followed 10 years later: (i) concordant couples in which husbands and wives engaged in low-risk alcohol consumption (n = 54); (ii) concordant couples in which husbands and wives engaged in high-risk alcohol consumption (n = 38); and (iii) discordant couples in which one partner engaged in high-risk alcohol consumption and the other partner did not (n = 75). At each follow-up, husbands and wives completed an inventory that assessed their personal, family and social functioning. FINDINGS: Compared to the low-risk concordant group, husbands and wives in the high-risk concordant group were more likely to rely on tension-reduction coping, reported more friend approval of drinking, and were less involved in religious activities; however, they did not differ in the quality of the spousal relationship. The frequency of alcohol consumption declined among husbands in discordant couples, but not among husbands in concordant couples. Predictors of high-risk drinking included tension-reduction coping, friend approval of drinking and, for husbands, their wives' level of drinking. CONCLUSIONS: High-risk and discordant alcohol consumption do not seem to be linked to decrements in family functioning among older couples in long-term stable marriages. The predictors of heavy alcohol consumption among older husbands and wives identify points of intervention that may help to reduce their high-risk drinking.


Subject(s)
Alcohol Drinking/epidemiology , Alcoholic Beverages/statistics & numerical data , Alcoholism/epidemiology , Social Adjustment , Spouses , Adaptation, Psychological , Adult , Age Factors , Aged , Alcohol Drinking/psychology , Alcoholism/psychology , Analysis of Variance , Attitude to Health , Family Characteristics , Family Health , Female , Follow-Up Studies , Health Status , Humans , Interpersonal Relations , Logistic Models , Male , Middle Aged , Sex Factors
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