[Influence of various levels of vitamin D and calcium in the diet on variability of microbes association of rats].

It is established, that the microecological system of intestines microbes association structurally reacts to the maintenance of vitamin D and calcium in food. Thus change of frequency of occurrence, the specific maintenance and a dispersion of separate components of system is observed. Besides character and force of correlation communications between concentration of microbes varies. The revealed principles of formation and change of microbic community of intestines enable to define mechanisms of selective management of microbic components microbes association.

[The adhesive properties of lactobacteria and escherichiae in different divisions of human gastrointestinal tract under normal and pathologic conditions].

A comparison of the adhesive properties of lactobacteria and escherichiae in different divisions of human gastrointestinal tract under normal and pathologic conditions was conducted. The study shows that the population changeability of the adhesive properties of lactobacteria and escherichiae is determined by localization of the strain in the gastrointestinal tract, and morphofunctional condition of the intestinal wall. Bacteria's adhesiveness to glycocalix of intestinal epithelial cells is higher in the left half of the colon than in the right one, and is still higher in feces. Their co-adhesiveness changes in the reverse order. Bacteria localized in the parietal mucin of inflamed segments, possess low capability of forming microcolonies, and high adhesiveness to glycocalix. The results of the study demonstrate that the choice of therapeutic probiotic bacterial strains should depend on the anatomic localization of the lesion and the character of gastrointestinal pathology.