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Bioorg Med Chem Lett
; 21(2): 869-73, 2011 Jan 15.
Article
in English
| MEDLINE
| ID: mdl-21195616
ABSTRACT
N-type calcium channels (Ca(v)2.2) have been shown to play a critical role in pain. A series of low molecular weight 2-aryl indoles were identified as potent Ca(v)2.2 blockers with good in vitro and in vivo potency.