Dual-task differences in individuals with chronic ankle instability: A systematic review with meta-analysis.

BACKGROUND: Individuals with Chronic Ankle Instability (CAI) demonstrate altered gait mechanics, impaired proprioception, and decreased postural control. In addition, individuals with CAI have been found to have complex neurophysiological changes, including during dual-task perturbations. However, the results of studies on whether cognitive tasks affect postural control are inconclusive. RESEARCH QUESTION: Do individuals with CAI have worse dual-task performance compared to healthy controls? METHODS: We searched 4 electronic databases (PubMed, MEDLINE, Cumulative Index of Nursing and Allied Health Literature, and SPORTDiscus) from inception to October 2022. Search terms consisted of: ("dual-task*" OR "dual task*" OR dual-task OR Multitask* OR Multi-task* OR attention OR cognit*) AND (balance OR "postural control" OR "postural sway" OR kinetics OR kinematics OR gait) NOT (concussion OR "traumatic brain injury") combined using the operator "AND" ("ankle sprain" OR "ankle instability" OR CAI). Studies were included if the physical task was postural control or gait, and if they compared control and CAI groups. RESULTS: A total of 9 studies were included in the systematic-review portion, 5 of which were included in the meta-analysis. Due to assessing multiple types of dual-tasks, 10 effects were assessed for meta-analysis across postural control studies. A random-effects model for the control group in the mediolateral direction indicated a significant overall Fisher's Z mean effect size (Δ = 0.732, p = 0.029) with high heterogeneity between studies (Q=76.61; I2 = 88.25% P < 0.001). There were no significant differences between dual-tasking in the CAI group individually or when comparing control to CAI groups. SIGNIFICANCE: The results of our study indicate that cognitive loading did not affect the postural control except for the control group in the mediolateral direction. Variations in dual-task results may be due to the difficulty of the task as well as the heterogeneity of CAI groups.

Participant-Level Analysis of the Effects of Interventions on Patient-Reported Outcomes in Patients With Chronic Ankle Instability.

CONTEXT: Intervention studies for chronic ankle instability (CAI) often focus on improving physical impairments of the ankle complex. However, using an impairments-focused approach may miss psychological factors that may mediate function and recovery. Patient-reported outcome (PRO) measures can be used to assess several dimensions of the health-related quality of life (HRQoL) and deliver enhanced patient-centered care. Therefore, the purpose of this investigation was to evaluate group-level improvements in HRQoL and treatment response rates following various interventions in patients with CAI. DESIGN: Cross-sectional. METHODS: Data from 7 previous studies were pooled by the chronic ankle instability outcomes network for participant-level analysis, resulting in 136 patients with CAI. Several interventions were assessed including balance training, gait biofeedback, joint mobilizations, stretching, and strengthening, with treatment volume ranging from 1 to 4 weeks. Outcome measures were PROs that assessed ankle-specific function (Foot and Ankle Ability Measure), injury-related fear (Tampa Scale of Kinesiophobia and Fear Avoidance Belief Questionnaire), and global well-being (Disablement in the Physically Active); the PROs assessed varied between studies. Preintervention to postintervention changes were evaluated using separate Wilcoxon signed-rank tests and effect sizes, and a responder analysis was conducted for each PRO. RESULTS: Significant, moderate to large improvements were observed in PROs that assessed ankle-specific function, injury-related fear, and global well-being following intervention (P < .001). Responder rates ranged from 39.0% to 53.3%, 12.8% to 51.4%, and 37.8% for ankle specific function, injury-related fear, and global well-being, respectively. CONCLUSIONS: Various interventions can lead to positive improvements in HRQoL in patients with CAI. Treatment response rates at improving HRQoL are similar to response rates at improving impairments such as balance, further reinforcing the need for individualized treatment approaches when treating a patient with CAI.

Association of Ankle Sprain Frequency With Body Mass and Self-Reported Function: A Pooled Multisite Analysis.

CONTEXT: Ankle sprains result in pain and disability. While factors such as body mass and prior injury contribute to subsequent injury, the association of the number of ankle sprains on body anthropometrics and self-reported function are unclear in this population. Therefore, the purpose of this investigation was to assess differences in anthropometric measurements and self-reported function between the number of ankle sprains utilizing a large, pooled data set. DESIGN: Cross-sectional. METHODS: Data were pooled from 14 studies (total N = 412) collected by the Chronic Ankle Instability Outcomes Network. Participants were categorized by the number of self-reported sprains. Anthropometric data and self-reported function were compared between those who reported a single versus >1 ankle sprain as well as among groups of those who had 1, 2, 3, 4, and ≥5 ankle sprains, respectively. RESULTS: Those who had >1 ankle sprain had higher mass (P = .001, d = 0.33) and body mass index (P = .002, d = 0.32) and lower Foot and Ankle Ability Measure-Activities of Daily Living (P < .001, r = .22), Foot and Ankle Ability Measure-Sport (P < .001, r = .33), and Cumberland Ankle Instability Tool (P < .001, r = .34) scores compared to the single ankle sprain group. Those who had a single ankle sprain weighed less than those who reported ≥5 sprains (P = .008, d = 0.42) and had a lower body mass index than those who reported 2 sprains (P = .031, d = 0.45). CONCLUSIONS: Some individuals with a history of multiple ankle sprains had higher body mass and self-reported disability compared to those with a single sprain, factors that are likely interrelated. Due to the potential for long-term health concerns associated with ankle sprains, clinicians should incorporate patient education and interventions that promote physical activity, healthy dietary intake, and optimize function as part of comprehensive patient-centered care.

Platelet-Rich Plasma versus Corticosteroid Injection for the Treatment of Lateral Epicondylitis: A Systematic Review of Systematic Reviews.

BACKGROUND: Lateral epicondylitis (LE) is one of the most commonly reported musculoskeletal disorders in the upper extremity. The mechanism of LE is repetitive motion that causes a strain of the extensor tendons. This consequently causes pain and tendinosis at the tendinous attachment site on the lateral epicondyle. Most cases of LE are treated nonoperatively with a variety of interventions, such as injections. PURPOSE: The aim of this systematic review (SR) is to synthesize the current evidence on the efficacy of platelet rich plasma (PRP) injections versus corticosteroid (CS) injections as treatment interventions for LE. STUDY DESIGN: Systematic Review. METHODS: Online databases were searched from database inception to February 24th, 2020 for relevant SR's evaluating PRP vs. CS injections as treatment methods for LE. Two independent researchers searched and screened for articles that were systematic reviews that directly compared PRP to CS injections for LE. RESULTS: A total of five SR's were included in this review that were published between 2016 and 2020. CS injections were more efficacious for short-term pain relief, and PRP injections were more efficacious for long-term pain relief and improved function. CONCLUSION: PRP injections appear to be a more effective long-term treatment option than CS injections for those with LE who did not respond to conservative management. LEVEL OF EVIDENCE: 1.

The effects of visual biofeedback and visual biofeedback scale size on single limb balance.

BACKGROUND: Controlling postural sway relies on the assessment and integration of external sensory stimuli by the central nervous system. When there is a loss of one or more of the sensory stimuli, there is often a decrease in balance performance. Visual biofeedback (VBF) has become a popular method to improve balance because of the supplementation to natural visual information with visual cues of the center of pressure. It is also possible to improve balance even further by increasing the scale of VBF. The aim of this investigation was to determine the effects of VBF and increasing VBF scale on single-limb balance in healthy adults. METHODS: Twenty healthy young adults were recruited. Participants underwent 24, 20-s single limb balance trials on both the right and the left leg. These trials were collected under 4 conditions: 1) eyes-open (EO) with no VBF, 2) EO with 1:1 scale VBF, 3) EO with 2:1 scale VBF, 4) EO with 5:1 scale VBF. Force plate outcomes included resultant, anterior-posterior, and medial-lateral Sway. A two-way repeated measures ANOVA was performed and a Bonferonni post-hoc test was used to determine the effects of VBF and VBF scale size on balance. RESULTS: Differences were noted in AP Sway and Resultant Sway when VBF was present and the scale size was increased (p < 0.05). CONCLUSION: Providing VBF decreases Sway in single-limb stance for young healthy adults, especially when the scale was increased beyond 1:1 VBF. These results may be clinically applicable for balance rehabilitation and training.

The reliability and validity of a digital version of the Cumberland Ankle Instability Tool.

PURPOSE: The Cumberland Ankle Instability Tool is a common patient reported outcome used to assess those with Chronic Ankle Instability. However, paper versions of the Cumberland Ankle Instability Tool have only been assessed for reliability purposes. The purpose of this study was to assess the agreement and reliability of a digital version of the Cumberland Ankle Instability Tool-Digital. MATERIALS AND METHODS: Sixty-eight participants with a history of ankle sprain(s) were recruited to participate in this study. Participants completed a paper version of the Cumberland Ankle Instability Tool and a digital version then returned one week later and completed them again. Intraclass correlation coefficients (ICC) and Kappa coefficients were used to determine the agreement between the paper and digital versions as well as test-retest reliability between the two time periods. RESULTS: The digital version showed excellent reliability (ICC = 0.93, 95% CI: 0.89-0.96) with the paper version. The test-retest reliability between testing sessions was considered good (ICC = 0.86, 95% CI: 0.77-0.92). A majority of individual items on the digital version demonstrated substantial agreement (κ = 0.60-0.81) with the paper version. CONCLUSIONS: A digital version of the Cumberland Ankle Instability Tool demonstrated good to excellent psychometric properties. Clinicians who utilize a digital version as part of an electronic medical record system can utilize them confidently to accurately assess patients with Chronic Ankle Instability. Future studies may want to consider assessing a digital version with expanded clinical and research populations.Implications for rehabilitationThe digital version of the Cumberland Ankle Instability Tool demonstrated adequate psychometric properties.The digital version of the Cumberland Ankle Instability Tool can be considered a reliable instrument for the assessment of Chronic Ankle Instability.A digital version of the Cumberland Ankle Instability Tool can provide automated scoring and quick administration for clinicians in a rehabilitation setting.

Does the Method of Administration Affect Reliability of the Foot and Ankle Ability Measure?

BACKGROUND: Region-specific patient-reported outcomes (PROs) are commonly used in rehabilitation medicine. Digital versions of PROs may be implemented into electronic medical records and are also commonly used in research, but the validity of this method of administration (MOA) must be established. PURPOSE: To determine the agreement between and compare the test-retest reliability of a paper version (FAAM-P) and digital version (FAAM-D) of the Foot and Ankle Ability Measure (FAAM). STUDY DESIGN: Randomized, nonblinded, crossover observational study. METHODS: A total of 90 adults were randomized to complete the FAAM-P or FAAM-D first, and then completed the second MOA (first day [D1]). The FAAM-D was a digital adaptation of both FAAM-P subscales on Qualtrics. Identical test procedures were completed 1 week later (D2). Data were removed if a participant scored 100% on both MOA, reported injury between D1 and D2, or did not complete both MOA. Agreement was assessed on 46 participants between the 2 MOA using intraclass correlation coefficients (ICC) at D1. There was good-to-excellent test-retest reliability for the FAAM activities of daily living. RESULTS: The authors observed good agreement between the FAAM-P and FAAM-D for the activities of daily living (ICC = .88) and sport scales (ICC = .87). Test-retest reliability was good-to-excellent for the FAAM activities of daily living (FAAM-P: ICC = .87; FAAM-D: ICC = .89) and sport (FAAM-P: ICC = .71; FAAM-D: ICC = .91). CONCLUSIONS: The MOA does not appear to affect the responses on the FAAM; however, the authors observed slightly higher reliability on the FAAM-D. The FAAM-D is sufficient to be used for generating practice-based evidence in rehabilitation medicine.

Cortical Measures of Motor Planning and Balance Training in Patients With Chronic Ankle Instability.

CONTEXT: Motor planning, a prerequisite for goal-driven movement, is a complex process that occurs in the cortex. Evidence has suggested that motor planning is altered in patients with chronic ankle instability (CAI). We know balance training can improve balance, but we do not know if it also improves motor planning. Such changes in cortical activity can be assessed using electroencephalography. OBJECTIVE: To evaluate changes in cortical measures of motor planning after balance training in patients with CAI. DESIGN: Controlled laboratory study. SETTING: Research laboratory. PATIENTS OR OTHER PARTICIPANTS: Fifteen patients with CAI (age = 20.80 ± 2.37 years, height = 169.47 ± 7.95 cm, mass = 70.45 ± 19.25 kg). INTERVENTION(S): A 4-week progression-based balance-training program. MAIN OUTCOME MEASURE(S): Motor planning was assessed via electroencephalography before a lateral-stepping task. We calculated event-related spectral perturbations in the θ (4-8 Hz), α (8-12 Hz), ß (14-25 Hz), and γ (30-50 Hz) bands. The change in power (in decibels) was calculated in each band for the 500 milliseconds before the onset of the lateral-stepping movement. Additional outcomes were the Foot and Ankle Ability Measure (FAAM)-Activities of Daily Living and Sport subscales; the anterior-, posteromedial-, and posterolateral-reach directions of the Star Excursion Balance Test; and static balance. Patients completed 3 test sessions: baseline, 24- to 48-hour posttest, and 1-week posttest. Repeated-measures analyses of variance were used to assess changes over time. The α level was set at .05. RESULTS: The FAAM-Activities of Daily Living subscale score was improved at both posttests (P < .05), and the FAAM-Sport subscale score was improved at the 1-week posttest (P = .008). Balance was better in all 3 directions of the Star Excursion Balance Test at both posttest sessions (P < .001). After balance training, no differences were identified in cortical activity at either posttest session (P > .05). CONCLUSIONS: No improvements were identified in electroencephalography measures of motor planning during lateral stepping in patients with CAI. Improved balance suggested that sensorimotor adaptations occurred, but they may not have transferred to the lateral-stepping task or they may have been mediated via other processes in patients with CAI.

The Effects of Cognitive Loading on Motor Behavior in Injured Individuals: A Systematic Review.

BACKGROUND: Research suggests that individuals with musculoskeletal injury may have difficulty negotiating physical tasks when they are combined with cognitive loads. OBJECTIVE: Our objective was to conduct a systematic review to understand the effects of increased cognitive demand on movement patterns among individuals with musculoskeletal injuries. METHODS: A comprehensive search of PubMed, MEDLINE, the Cumulative Index for Nursing and Allied Health Literature (CINAHL), and SPORTDiscus was conducted to find research reports that included a population that had previously experienced an ankle, knee, or low back injury, included an uninjured control group, and assessed a dual-task paradigm. RESULTS: Forty-five full-text research reports were assessed, of which 28 studies (six ankle injury, nine knee injury, and 13 low back pain studies) were included in the review. Included studies were assessed for methodological quality and the study design extracted for analysis including the participants, cognitive and physical tasks performed, as well as outcome measures (e.g., three-dimensional kinematics, center of pressure, etc.). All studies included were cross-sectional or case-control with methodological quality scores of 17.8 ± 2.2 out of a possible 22. Twenty-five of the 28 studies found changes in motor performance with dual-task conditions compared with single tasks. Furthermore, 54% of studies reported a significant group by task interaction effect, reporting at least one alteration in injured groups' motor performance under dual-task conditions when compared with an uninjured group. CONCLUSION: The results of this systematic review indicate that motor performance is further impaired by placing a cognitive load on individuals in populations with musculoskeletal injury. More demanding tasks such as gait appear to be more affected in injured individuals than simple balance tasks. Future investigators may want to consider the difficulty of the tasks included as well as the impact of dual-task paradigms on rehabilitation programs.

Predicting dynamic balance improvements following 4-weeks of balance training in chronic ankle instability patients.

OBJECTIVES: Balance training typically features as a central component of exercise-based rehabilitation programs for patients with lateral ankle sprain and chronic ankle instability (CAI). The purpose of this study was to conduct a responder/non-responder analysis using existing data to identify factors associated with improvements in dynamic balance performance in CAI patients. DESIGN: Secondary data analysis. METHODS: Data was used from 73 CAI patients who participated in 6 previous investigations that used the same balance training program. We defined treatment success as a patient exceeding the minimal detectable change score (8.15%) for the posteriomedial direction of the Star Excursion Balance Test (SEBT-PM). Baseline measures of participant and injury demographics, patient-reported function, and dynamic balance were entered into a step-wise logistic regression model to determine the best set of predictors of treatment success. RESULTS: Only 28 out of 73 patients (38.4%) demonstrated a successful improvement in SEBT-PM reach after balance training. Of the variables assessed, SEBT-PM reach distance ≤85.18% and self-reported function activities of daily living score ≤92.55% were significant predictors of treatment success (p<0.001). If a patient met both these criteria there was a 70% probability of a successful treatment, indicating a 31.6% increase in the probability of a meaningful balance improvement after completing balance training. CONCLUSIONS: Without screening, less than 40% of CAI patients experience a meaningful improvement in SEBT-PM following balance training. Completing a brief pre-treatment assessment of a patient- and clinician-oriented outcome can significantly improve the probability of determining patients with CAI who may improve dynamic balance after balance training.

Balance Training Versus Balance Training With STARS in Patients With Chronic Ankle Instability: A Randomized Controlled Trial.

CONTEXT: Both balance training and selected interventions meant to target sensory structures (STARS) have been shown to be effective at restoring deficits associated with chronic ankle instability (CAI). Clinicians often use multiple treatment modalities in patients with CAI. However, evidence for combined intervention effectiveness in CAI patients remains limited. OBJECTIVE: To determine if augmenting a balance-training protocol with STARS (BTS) results in greater improvements than balance training (BT) alone in those with CAI. DESIGN: Randomized-controlled trial. SETTING: Research laboratory. PATIENTS: 24 CAI participants (age 21.3 ± 2.0 y; height 169.8 ± 12.9 cm; mass 72.5 ± 22.2 kg) were randomized into 2 groups: BT and BTS. INTERVENTIONS: Participants completed a 4-week progression-based balance-training protocol consisting of 3 20-min sessions per week. The experimental group also received a 5-min set of STARS treatments consisting of calf stretching, plantar massage, ankle joint mobilizations, and ankle joint traction before each balance-training session. MAIN OUTCOME MEASURES: Outcomes included self-assessed disability, Star Excursion Balance Test reach distance, and time-to-boundary calculated from static balance trials. All outcomes were assessed before, and 24-hours and 1-week after protocol completion. Self-assessed disability was also captured 1-month after the intervention. RESULTS: No significant group differences were identified (P > .10). Both groups demonstrated improvements in all outcome categories after the interventions (P < .10), many of which were retained at 1-week posttest (P < .10). Although 90% CIs include zero, effect sizes favor BTS. Similarly, only the BTS group exceeded the minimal detectable change for time-to-boundary outcomes. CONCLUSIONS: While statistically no more effective, exceeding minimal detectable change scores and favorable effect sizes suggest that a 4-week progressive BTS program may be more effective at improving self-assessed disability and postural control in CAI patients than balance training in isolation.

Effects of a stocking on plantar sensation in individuals with and without ankle instability.

INTRODUCTION: It is unknown whether footwear has a beneficial or deleterious effect on cutaneous sensitivity. We aimed to test a preliminary model of footwear and its effect on tactile perception among groups of controls, copers, and chronic ankle instability participants. METHODS: Light-touch thresholds were obtained for 45 participants (age: 20.2 ± 2.8 years; height: 167.6 ± 9.8 cm; mass: 66.3 ± 14.7 kg) using Semmes-Weinstein monofilaments at the head of the first metatarsal (1MT), base of the fifth metatarsal (5MT), and calcaneus (CAL). Baseline measurements were compared with those taken after wearing a nylon stocking for 5 min. RESULTS: Thresholds were increased at all 3 sites when the stocking was worn (P < 0.05). Controls had an increase at 1MT, copers had an increase at 5MT and CAL, and chronic ankle instability had an increase at CAL. CONCLUSIONS: Cutaneous thresholds increase when subjects wear a nylon stocking, a model for the sensory effects of footwear. A history of ankle injury appears to influence which sites have altered sensibility. Muscle Nerve, 2016. Muscle Nerve 55: 513-519, 2017.

Increased Visual Use in Chronic Ankle Instability: A Meta-analysis.

PURPOSE: The underlying cause of balance impairments in chronic ankle instability (CAI) patients remains unknown, but an altered use of sensory information has been hypothesized as a potential cause. The purpose of this systematic review with meta-analysis was to determine whether CAI patients use somatosensory information to the same extent as uninjured controls during static single limb stance. METHODS: We searched PubMed, CINAHL, SPORTDiscus, and Scopus databases from origin to March 2016 using the combination of key words, including postural control, postural stability, single limb stance, single leg stance, single leg balance, single limb balance, and time to boundary (TTB). Eligible studies had to include instrumented single leg stance with both eyes open and eyes closed in healthy, CAI, or both groups as well as report TTB mean and SD values. RESULTS: A total of 11 articles were identified. Effect sizes using eyes closed to eyes open standardized mean differences and 95% confidence intervals were calculated for all studies that were included in this investigation. Similarly, pooled estimates for each TTB outcome were compared between the CAI and the uninjured control groups. The mean (95% confidence interval) of the mediolateral TTB (control: -1.50 [-1.71 to -1.29]; CAI: -2.04 [-2.31 to -1.77]), anterioposterior mean (control: -2.19 [-2.43 to -1.96]; CAI: -2.82 [-3.13 to -2.52]), and anterioposterior SD (control: -1.81 [-2.03 to -1.58]; CAI: -2.50 [-2.79 to -2.22]) did not overlap, indicating significant differences between two groups. CONCLUSION: On the basis of our systematic review with meta-analysis, it appears that CAI patients do not use somatosensory information to the same extent as uninjured controls and instead upregulate the use of visual information during single limb stance.

Cognitive loading-induced sway alterations are similar in those with chronic ankle instability and uninjured controls.

Performing a cognitive task while balancing can result in either increased or decreased sway depending on the nature of the cognitive task, and is commonly used in pathologic populations to evaluate postural performance. A total of 39 participants were recruited into two groups: uninjured controls (n=20, age: 21.9±2.1 years, height: 175.0±11.2cm, mass: 71.3±14.9kg) and chronic ankle instability (n=19, age: 22.1±5.6 years, height: 169.7±7.7cm, mass: 72.9±17.3kg). Participants were asked to perform one of three cognitive tasks while maintaining single limb balance. Cognitive tasks included backwards counting by 3 (BC), the manikin test (MAN), and random number generation (RNG). Time-to-boundary minima, mean, and standard deviations were calculated and compared between groups as pre to post change scores. Effect sizes and 95% confidence intervals were also calculated to test for group differences and the effect of task performance on sway. No significant main effects of Group or Group by Task interactions were identified (p>0.05). However, a significant multivariate main effect of Task was identified in BC (p=0.001, F(6, 32)=4.804) and RNG (p<0.001, F(6, 32)=6.233) but not for MAN (p=0.117). The results suggest that those with chronic ankle instability and uninjured controls have similar postural-suprapostural interactions across multiple cognitive task domains. Both the BC and RNG tasks resulted in less sway for all participants. Our results suggest that dual-task interference in the CAI population may not be present as previous research would suggest.

Plantar Cutaneous Sensitivity With and Without Cognitive Loading in People With Chronic Ankle Instability, Copers, and Uninjured Controls.

STUDY DESIGN: Controlled laboratory study. BACKGROUND: Deficits in light touch have recently been identified on the plantar surface of the foot in those with chronic ankle instability (CAI) but not in uninjured controls. It is unknown whether copers display similar deficits. Similarly, cognitive loading has been shown to impact postural control in different populations, but it is unclear how it may impact sensory perception. OBJECTIVES: To evaluate the difference in cutaneous sensation thresholds at rest and under cognitive loading, using Semmes-Weinstein monofilaments (SWMs), among uninjured controls, copers, and those with CAI. METHODS: A total of 45 participants (mean ± SD age, 20.2 ± 2.8 years; height, 167.6 ± 9.9 cm; mass, 66.3 ± 14.7 kg) were recruited and categorized to a CAI, coper, or control group, based on Ankle Instability Instrument scores. Participants were assessed with SWMs for cutaneous thresholds using a 4-2-1 stepping algorithm at the head of the first metatarsal, base of the fifth metatarsal, calcaneus, and sinus tarsi. Each participant was then retested while generating random digits to the beat of a metronome in order to simulate cognitive loading. RESULTS: Participants with CAI displayed significantly higher SWM thresholds at the head of the first metatarsal, base of the fifth metatarsal, and sinus tarsi than those of the control participants, and significantly higher thresholds at the base of the fifth metatarsal and calcaneus than those of copers (all, P<.05). Copers showed higher thresholds than those of controls at the sinus tarsi only (P<.05). A main effect of cognitive loading was identified at all 4 sites (P<.05). CONCLUSION: People with CAI have deficits in plantar sensation relative to controls and copers. Cognitive loading increases plantar cutaneous sensation thresholds irrespective of CAI status.

The effect of instructions on postural-suprapostural interactions in three working memory tasks.

Examining postural control while simultaneously performing a cognitive, or suprapostural task, has shown a fairly consistent trend of improving postural control in young healthy adults and provides insight into postural control mechanisms used in everyday life. However, the role of attention driven by explicit verbal instructions while dual-tasking is less understood. Therefore, the purpose of this investigation is to determine the effects of explicit verbal instructions on the postural-suprapostural interactions among various domains of working memory. A total of 22 healthy young adults with a heterogeneous history of ankle sprains volunteered to participate (age: 22.2±5.1 years; n=10 history of ankle sprains, n=12 no history). Participants were asked to perform single-limb balance trials while performing three suprapostural tasks: backwards counting, random number generation, and the manikin test. In addition, each suprapostural task was completed under three conditions of instruction: no instructions, focus on the postural control task, focus on the suprapostural task. The results indicate a significant effect of instructions on postural control outcomes, with postural performance improving in the presence of instructions across all three cognitive tasks which each stress different aspects of working memory. Further, postural-suprapostural interactions appear to be related to the direction or focus of an individual's attention as instructions to focus on the suprapostural task resulted in the greatest postural control improvements.Thus, attention driven by explicit verbal instructions influence postural-suprapostural interactions as measured by a temporal-spatial postural control outcome, time-to-boundary, regardless of the suprapostural task performed.