Mandibular Myxoid Liposarcoma: a Case Study.

Liposarcomas are described as soft tissue sarcomas derived from adipose tissue. The finding of this tumor in the mandibular region is exceedingly rare. As of now, it has been described mainly in case reports and small series. A multidisciplinary approach is required to offer optimal treatment and may involve surgery, radiation and systemic therapies. Surgical repair of these defects represents a major challenge in oral and maxillofacial reconstructive surgery. We present the case of a 54-year-old man referred to our center with a progressively increasing mass in the anterior portion of the mandible. Biopsy revealed a well-differentiated myxoid liposarcoma. Resection of the tumor was performed with an additional primary reconstruction.

Relación entre dimensiones antropométricas de tronco y valores de espirometría / Association between anthropometric dimensions of trunk and spirometry indices

Los objetivos del presente estudio fueron primero evaluar la asociación de dimensiones antropométricas de tórax y tronco con índices espirométricos, segundo, ajustar una ecuación de predicción con dimensiones antropométricas de tronco y tercero, comparar nuestro modelo predictivo con dos ecuaciones diagnósticas. Se evaluaron 59 estudiantes universitarios entre 20 y 40 años, de ambos sexos, sin hábito tabáquico. Las variables consideradas fueron: edad, sexo, peso, estatura, diámetro transverso de tórax, diámetro anteroposterior de tórax, perímetro de tórax, altura de tórax, altura de tronco, flujo espiratorio máximo (FEM), volumen espiratorio forzado en el primer segundo (VEF1) y capacidad vital forzada (CVF). Se utilizó el análisis de regresión múltiple para estimar los valores espirométricos en función de las variables demográficas y antropométricas. La CVF y el VEF1 tienen asociación lineal directa con el diámetro transverso de tórax, altura de tórax, perímetro de tórax y altura de tronco. Se ajustó una ecuación de regresión lineal múltiple que indicó que es posible estimar la CVF y el VEF11 en función de la altura de tronco y el perímetro de tórax para ambos sexos. Estas variables son capaces de explicar el 74 % de los valores de CVF y el 68 % de los valores de VEF1. Al comparar los valores obtenidos por nuestras ecuaciones predictivas con las ecuaciones de referencia nacional observamos que nuestros resultados son más cercanos a los de Quanjer et al. (2012) que a los de Knudson et al. (1983). La altura de tronco y el perímetro de tórax tienen asociación directa con el VEF1 y CVF y son buenos predictores del VEF1 y CVF en estudiantes universitarios. Nuestros valores estimados son más cercanos a las ecuaciones de Quanjer et al. (2012) en comparación a las estimaciones de Knudson (1983).

SUMMARY: The purposes of the present study were first to evaluate the association between anthropometric dimensions of the thorax and trunk with spirometric indices, second, to fit a prediction equation with anthropometric dimensions of the trunk, and third, to compare our predictive model with two diagnostic equations. Fifty-nine university students between 20 and 40 years old, of both sexes and non-smokers were recruited. Variables considered were age, sex, weight, height, chest transverse diameter, chest anteroposterior diameter, chest perimeter, chest height, trunk height, maximum expiratory flow (PEF), forced expiratory volume in the first second (FEV1) and forced vital capacity (FVC). Multiple regression analysis was used to estimate spirometric values based on demographic and anthropometric variables. FVC and FEV1 have a direct linear association with chest transverse diameter, chest height, chest circumference, and trunk height. A multiple linear regression equation was fitted, indicating that it is possible to estimate FVC and FEV1 as a function of trunk height and chest girth for both sexes. These variables can explain 74% of the FVC values and 68% of the FEV1 values. Comparing the values obtained by our predictive equations with the national reference equations, we observe that our results are closer to those of Quanjer et al. (2012) than to those of Knudson et al. (1983). Trunk height and chest circumference have a direct association with FEV1 and FVC and are good predictors of FEV1 and FVC in university students. Our estimated values are closer to Quanjer et al. (2012) than Knudson et al. (1983) prediction equations.

Unusual Delayed Complication of Pacemaker Leads.

We present three patients who complained of chest pain secondary to displaced pacemaker leads. They underwent evaluation in the emergency room multiple times for chest pain. Imaging was useful to diagnose misplaced ventricular leads of the pacemaker. The patients needed a pericardial window for the extraction of leads and repair of the heart defect. The perioperative course was managed with a multidisciplinary team of cardiologists and electrophysiologists.

Angiosarcoma de aurícula derecha irresecable / Unresectable right atrial angiosarcoma

Resumen Se presenta el caso de un paciente masculino de 41 años de edad con derrame pericárdico y una masa intra cardíaca (mixoma like) que producía un efecto valvular sobre el plano tricuspídeo. Debido a la imposibilidad de realizar una cirugía radical y un diagnóstico anátomo-patológico, se decidió realizar un explante total y un trasplante cardíaco ortotópico en un segundo tiempo, concretado exitosamente a los 23 días después de la cirugía diagnóstica.

We present the case of a 41-year-old male patient with pericardial effusion and intra cardiac mass, mixoma like, which produces a valve effect in the tricuspid valve. Due to the impossibilities to perform a radical surgery and the anatomopathological diagnosis we decided to do a total explant and perform an orthotopic heart transplant. The impossibility to perform a radical surgery and the diagnosis of angiosarcoma of cells fused, decided us to perform a total cardiac explant and an orthotopic heart transplant finally realized in the second surgical time, 23 days after the diagnostic surgery.

Apresentamos o caso de um paciente masculino de 41 anos de idade com derrame pericárdico e uma massa intra cardíaca (mixoma like) que produz um efeito de valvular sobre o plano tricuspídeo. Devido às impossibilidades para realizar uma cirurgia radical, e o diagnóstico anatomopatológico decidimos realizar um explante total e um transplante cardíaco ortotópico num segundo tempo, concretado aos 23 dias após a cirurgia diagnóstica.

Immunocytochemical reaction of sera from chagasic patients against trypanosoma cruzi, intestine of triatoma infestans and normal human heart

Chagas disease has been considered by some authors as an autoimmune pathology and denied by others. In this paper we present by means of immunocytochemical reactions with sera of chagasic patients, evidence in favor of the presence of similar antigens in the parasite, vector and non chagasic human heart. The immunocytochemical technique used permits the localization by electron microscopy of the antigens in the peritrophic membrane of the parasite and basement membranes of the vector´s midgut and of the myosin band of the normal human heart. These observations support the assumption of an autoimmune response in Chagas disease. (AU)

Immunocytochemical reaction of sera from chagasic patients against trypanosoma cruzi, intestine of triatoma infestans and normal human heart

Chagas disease has been considered by some authors as an autoimmune pathology and denied by others. In this paper we present by means of immunocytochemical reactions with sera of chagasic patients, evidence in favor of the presence of similar antigens in the parasite, vector and non chagasic human heart. The immunocytochemical technique used permits the localization by electron microscopy of the antigens in the peritrophic membrane of the parasite and basement membranes of the vectorïs midgut and of the myosin band of the normal human heart. These observations support the assumption of an autoimmune response in Chagas disease.