ABSTRACT
BACKGROUND: Allergic rhinitis and asthma as single entities affect more boys than girls in childhood but more females in adulthood. However, it is unclear if this prevalence sex-shift also occurs in allergic rhinitis and concurrent asthma. Thus, our aim was to compare sex-specific differences in the prevalence of coexisting allergic rhinitis and asthma in childhood, adolescence and adulthood. METHODS: Post-hoc analysis of systematic review with meta-analysis concerning sex-specific prevalence of allergic rhinitis. Using random-effects meta-analysis, we assessed male-female ratios for coexisting allergic rhinitis and asthma in children (0-10 years), adolescents (11-17) and adults (> 17). Electronic searches were performed using MEDLINE and EMBASE for the time period 2000-2014. We included population-based observational studies, reporting coexisting allergic rhinitis and asthma as outcome stratified by sex. We excluded non-original or non-population-based studies, studies with only male or female participants or selective patient collectives. RESULTS: From a total of 6539 citations, 10 studies with a total of 93,483 participants met the inclusion criteria. The male-female ratios (95% CI) for coexisting allergic rhinitis and asthma were 1.65 (1.52; 1.78) in children (N = 6 studies), 0.61 (0.51; 0.72) in adolescents (N = 2) and 1.03 (0.79; 1.35) in adults (N = 2). Male-female ratios for allergic rhinitis only were 1.25 (1.19; 1.32, N = 5) in children, 0.80 (0.71; 0.89, N = 2) in adolescents and 0.98 (0.74; 1.30, N = 2) in adults, respectively. CONCLUSIONS: The prevalence of coexisting allergic rhinitis and asthma shows a clear male predominance in childhood and seems to switch to a female predominance in adolescents. This switch was less pronounced for allergic rhinitis only.
ABSTRACT
BACKGROUND: The current study explored the association between green space and depression in a deprived, multiethnic sample of pregnant women, and examined moderating and mediating variables. METHOD: 7547 women recruited to the 'Born in Bradford' cohort completed a questionnaire during pregnancy. A binary measure of depressive symptoms was calculated using a validated survey. Two green space measures were used: quintiles of residential greenness calculated using the normalised difference vegetation index for three neighbourhood sizes (100, 300 and 500 m buffer zones around participant addresses); access to major green spaces estimated as straight line distance between participant address and nearest green space (>0.5 hectares). Logistic regression analyses examined relationships between green space and depressive symptoms, controlling for ethnicity, demographics, socioeconomic status (SES) and health behaviours. Multiplicative interactions explored variations by ethnic group, SES or activity levels. Mediation analysis assessed indirect effects via physical activity. RESULTS: Pregnant women in the greener quintiles were 18-23% less likely to report depressive symptoms than those in the least green quintile (for within 100 m of green space buffer zone). The green space-depressive symptoms association was significant for women with lower education or who were active. Physical activity partially mediated the association of green space, but explained only a small portion of the direct effect. CONCLUSIONS: Higher residential greenness was associated with a reduced likelihood of depressive symptoms. Associations may be stronger for more disadvantaged groups and for those who are already physically active. Improving green space is a promising intervention to reduce risk of depression in disadvantaged groups.
Subject(s)
Depression/psychology , Environment Design , Exercise , Pregnant Women/psychology , Residence Characteristics/statistics & numerical data , Social Class , Adult , Depression/diagnosis , Environment , Female , Health Behavior , Health Surveys , Humans , Longitudinal Studies , Pregnancy , Socioeconomic Factors , Surveys and QuestionnairesABSTRACT
EMIC-Chile (Entrenamiento en Metodologíaspara la Investigación Clínica en Chile) es un proyecto académico desarrollado durante el año 2008 en Chile para entrenar a profesionales de la salud y disciplinas afines en metodología de investigación clínica, con el objetivo de aumentar la calidad de los proyectos de investigación con fines concursables en nuestro país. El propósito de este artículo es dar a conocer el programa y sus fundamentos teóricos de enseñanza-aprendizaje, que estuvieron en la base de la estructura, metodología, evaluación y sistematización del conocimiento entregado. Para ello, primero se describe el programa, la metodología, la evaluación y el seguimiento. Posteriormente se detallan los aspectos psicoeducativos considerados, con especial énfasis en el aprendizaje social y la educación de adultos. Finalmente, se discute en torno alas posibles consideraciones de este programa para futuras intervenciones educativas en investigación en salud en Chile. Se espera que esta experiencia y sus fundamentos educativos sirvan de motor para futuras iniciativas en el área, afavor de la investigación en salud en Chile (AU)
Abstract. EMIC-Chile (Entrenamiento en Metodologías parala Investigación Clínica en Chile) is an academic project developed in Chile during 2008 to train health professionals in clinical research. The purpose of this initiative was to improve the quality of research projects that are submitted to apply for public funding. The aim of this article is to describe the psycho-educative theories that supported this training program, its structure, methods and evaluation. Firstly, the program is described in detail. Secondly, psycho-educative theories are described, with special emphasis of social learning theory and education for adults. Finally, implications of EMIC-Chile are stated, in order to improve future research training experiences in Chile. It is expected that this article enhance other research experts to create and develop new training programs in this field. This should progressively strength clinical research in our country (AU)